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Biomedical subjects

M Papillon

Publications and source records attributed to M Papillon.

15 recordsLinked to original sources

[Assessment of quality of life after antireflux surgery].

AIM OF THE STUDY: To assess the quality of life (QoL) of patients operated for gastroesophageal reflux disease (GERD). PATIENTS AND METHODS: This prospective study included 82 consecutive patients submitted to antireflux surgery between October 1998 and January 1999. A new questionnaire was used to assess their QoL: the Gastrointestinal Quality of Life Index (GIQLI) that includes 36 items concerning 5 dimensions: symptoms, vitality, emotions, social relations and medical treatment. The series consisted of 44 men and 38 women with a mean age of 47 years (range: 18-78). QoL was assessed before and 6 months after surgery; the follow-up rate was 94% (77/82). The pre- and postoperative GIQLI scores of the study group and the GIQLY score of a control group of 110 healthy patients were compared. RESULTS: Before surgery, the GIQLI score (90 +/- 23) was greatly impaired compared to the score (123 +/- 13) observed in the control group (p < 0.001). After surgery, the GIQLI score (110 +/- 23) increased significantly (p < 0.001), but remained statistically lower than the score of the control group (p < 0.001). The postoperative score recorded in the symptoms dimension was lower than the control group score: 55 +/- 11 versus 66 +/- 6 (p < 0.001), while no significant difference was observed in the other 4 dimensions. Univariate statistical analysis revealed that the postoperative GIQLI score (y) was correlated with the preoperative GIQLI score (x) according to the formula: y = 0.43 x + 71 (p < 0.001) and the sex of the patients, as the postoperative GIQLI score was higher in male patients (115 +/- 19) than in female patients (103 +/- 23) (p < 0.02). CONCLUSION: The QoL of the patients was greatly improved after antireflux surgery, but remained lower than that of a control group of healthy subjects. Better patient selection should improve the results. In our series, male patients or patients with a high preoperative GIQLI score were the best candidates for antireflux surgery.

Adolescent↗

[Treatment of hemorrhoids with the Longo technique. Preliminary results of a prospective study on 94 cases].

AIM OF STUDY: The aim of this multicenter prospective study was to report the early results of Longo procedure for the surgical treatment of hemorrhoids disease. PATIENTS AND METHOD: From April 1998 to July 1998, 94 patients (60 men and 34 women with a mean age of 47 years) were treated according to Longo procedure for a mucosal prolapse (12 grade II, 63 grade III, and 19 grade IV). All patients were evaluated at 2 and 6 postoperative months. The technique consisted in the reduction of mucosal and hemorrhoidal prolapses with a circular suturing device. RESULTS: Postoperative morbidity rate was 6.3% (n = 6). A rectal bleeding occurred within 12 hours after surgery in five patients. The mean postoperative length of hospital stay was 36 hours (range: 24-72 hours). The only antalgic prescribed was paracetamol. Local care was not necessary in any patient. After 6 months, 89 patients (94.7%) were very satisfied, three patients (3.2%) were satisfied (rectal sub-mucosal abscess in one case, functional troubles in two cases) and two patients (2.1%) were not satisfied (persistence of mucosal prolapse). CONCLUSION: These preliminary results are satisfactory but need to be confirmed by a prospective randomized trial, comparing Milligan Morgan procedure and Longo procedure.

Digestive System Surgical Procedures↗

[Role of preoperative radiotherapy in preservation of the anal sphincter in cancer of the lower rectum].

Short term preoperative irradiation of rectal cancer (30 Gy in 12 days) followed by a two-month rest before surgery has proven to be more efficient than most usual protocols of radiotherapy. In a series of 136 tumors T2, T3 or T4, tumor-free specimens and Duke'A lesions were found at surgery in 17% and 36% respectively. Surgeons took advantage of the tumor regression and performed sphincter-saving surgery in 41 patients with T2, T3 or T4 tumors of the lower third of the rectum. Of 30 patients followed from 2 to 6 years, the disease-free survival rate is 86%. Only one local failure was observed and subsequently controlled by abdomino-perineal resection.

Amputation, Surgical↗

[Low colorectal suture with the EEA stapling device for carcinoma of the rectum. A report of 50 cases (author's transl)].

50 cases of low colorectal anastomosis (between 3 to 10 cm from the anal verge) are reported. They have been done with the EEA stapling device after resection for rectal or rectosigmoïdal carcinomas. The peroperative incidents (5 cases) and details to prevent them are described. A protective colostomy was done in 10 cases. No leak had been observed. Recurrency and suture line stenosis are discussed. No anal incontinency, even for very low anastomosis had been observed.

Colon↗

[Tuberculosis of the breast. A revue of the literature in connection with a personal case (author's transl)].

The authors, having had a personal case that they report, have carried out a general review of tuberculosis of the breast. It is a rare affection which usually attacks women during reproductive life, mainly because of the influence of hormones on the condition. Clinically it is difficult to differentiate it from cancer and it can present in two forms, a superficial and a deep one, a diffuse one and a circumscribed one. All the same, there is a definite feature which is fistula formation. The diagnosis depends on the biopsy, which shows specific histological lesions, and on the bacteriological examination, which shows the Koch's bacillus. Mammography is not very characteristic and thermography is of too recent appearance. Treatment consists in anti-tuberculous chemotherapy at first, surgery being reserved for residual lesions.

Aged↗