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Biomedical subjects

M Paradowski

Publications and source records attributed to M Paradowski.

25 records · Page 2Linked to original sources
PubMed1981

[Analysis of the methods of evaluation of occupational exposure to benzene and phenol of petrochemical industry workers].

209 workers exposed to airborne benzene and phenol at the Mazovian Refining Petrochemical Works, at three different plants, i.e. of Phenol, Gasoline Composing and Water -- Wastes, have been examined. It has been demonstrated that urine phenol content in workers working in an open plant area is very often inadequate to the airborne time-weighted averaged concentration of benzene and phenol. It has been shown more advisable to determine urine phenol concentrations twice: before and after the work shift. At the same time some specific methods have been recommended for determining phenol concentrations in urine. These are: gas chromatographic method of Dirmikis and Darbre, modified in this laboratory, and Gibbs' colorimetric method modified by Bardodej with 4-amino-antipyrine or Gibbs' colorimetric method with 2,6-dibromoquinone-4-chloroimide modified by Hanke et al. The Theis-Benedict method should not be applied in medical analytical laboratory because of its low specificity to phenol.

Adult↗
PubMedDate not supplied

Influence of rectus eye muscles tenotomy on the aqueous humor composition in rabbits.

INTRODUCTION: Anterior segment ischaemia manifesting in aqueous malformation may follow tenotomy of the extraocular muscles. MATERIAL AND METHODS: Tenotomy of 2 or 4 rectus eye muscles was performed on the right eyes of 23 adult rabbits. The aqueous humor was withdrawn from the anterior chamber of both eyes in 7 rabbits on the 11th, on the 22nd in 8 and on the 32nd postoperative day in 8 rabbits. Aqueous natrium, potassium and glucose concentrations and protein electrophoresis were examined. RESULTS: The only significant change was lower mean aqueous potassium concentration in the operated eyes as compared to controls on the 11th postoperative day. CONCLUSION: Tenotomy of rectus eye muscles in healthy rabbits evoked a discrete blood-aqueous barrier break-down.

Albumins↗
PubMedDate not supplied

The effect of chronic exposure to formaldehyde, phenol and organic chlorohydrocarbons on peripheral blood cells and the immune system in humans.

The aim of this study was to evaluate immunological, hematological and biochemical parameters in subjects chronically exposed to inhaled formaldehyde (F), phenol (Ph) and isomers of organic chlorohydrocarbons (Chc) released from Ksylamit. Twenty-two office workers had been exposed for 6 months to vapors of Ksylamit, used for protection of felt plates inside the office building. The concentration of Ksylamit vapor was measured at the end of the 6-month period and the level of Ph and F in the air inside the building was 1.3 mg/m3 and 0.8 mg/m3, respectively. Most of the workers had ailments due to the irritant effect of inhaled Ksylamit, but no remarkable increase in morbidity was found during the 6 months of exposure and in a 3-year follow-up. Morphological parameters of blood and the number of natural killer (NK) cells in the group of exposed subjects were within the range observed in healthy subjects matched for age and sex. The number of T-lymphocytes and NK cell cytotoxicity were significantly decreased. Phytohemagglutinin (PHA)- and alloantigen-induced lymphocyte proliferation was diminished. Some biochemical parameters suggested liver damage, although these parameters did not correlate with the levels of Ph and methanol excreted in the urine. Eight subjects with the highest levels of Ph in the urine had decreased erythrocyte and T-helper lymphocyte numbers, and increased numbers of eosinophils and monocytes. The results obtained prove that the functions of both the immune and hematopoietic systems could be affected by chronic exposure to these toxic substances.

Adult↗