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Biomedical subjects

M Parravicini

Publications and source records attributed to M Parravicini.

10 recordsLinked to original sources

Tuberculosis and Pelger-Huët anomaly. Case report.

We describe a patient with pulmonary tuberculosis and a rare disturbance of leukocyte segmentation, known as "Pelger-Huët anomaly", which can be observed in various diseases such as malignancies and/or infections. The importance of this association is equivocal: some authors have related to the association the particular severity of tuberculosis or the death they observed; in the case reported we noted no evidence of such a relation, notwithstanding the presence of the homozygous form of the Pelger-Huët anomaly. We suggest therefore that, when Pelger-Huët anomaly is found, an underlying disease should be searched for; the course of this illness, however, might not be affected.

Adult↗

[Seminal fluid today].

Semen analysis is still today a fundamental stage in male fertility diagnosis. In fact it's essential to evaluate didimal functional state and particularly the sperm genesis. But a semen analysis with normal parameters does not assure male fertility. Except the cases of azoospermia it does not distinguishes fertile from infertile patients, but when the sperm quality decrease, the pregnancy rate also decrease but rarely touch zero. Reliability of the analysis depends on the experience and on the analyst's ability who has to give an opinion about fundamental parameters like motility and sperm morphology. It is most correct to talk about semen analysis instead of semen examination because is possible to obtain not only number and quality of spermatozoa but also hormonal, immunological, bacteriological, cytogenetic, biomolecular data. Furthermore in the last ten years a lot of functional tests have been perfected, able to value accurately the integrity of some spermatozoa's "functional compartments" like membrane, acrosoma, DNA, nuclear proteins but these examinations have been considered at level assessment only for select cases. Semen analysis remains therefore a fundamental examinations in the study of male infertility even if rarely it is able to express definitive trials about infertility. In fact this always represents a couple problem, particularly of the couple in study.

Chromosome Aberrations↗

[Surgery in day hospital: scrotal surgery].

Actually scrotal ambulatory surgery represents a necessity for the surgeon because of the more and more greatest request to admittance and because of the impossibility to admit patients with less severe diseases. Ambulatory treatments allows psychological advantage, less discomfort, less hospital complications for the patients and a reduction of sanitary expense. Light general anaesthesia with concomitant administration of local anaesthesia is performed in our Institute. Surgical treatment must be short, with low haemorragic risk, scarcely algogenic and aseptic. Since January 1994 till December 1997, 484 patients underwent scrotal ambulatory surgery in our Institute. We reported one cardiac black and two lypothymia attacks associated with anaesthesia. Therefore combined general anaesthesia results a valid technique but unvoid of complications. Ambulatory surgery for scrotal surgery represents a sure advantage for patients and for the sanitary expense.

Adolescent↗

Prolonged ECG abnormalities in a subject with high altitude pulmonary edema (HAPE).

High Altitude Pulmonary Edema (HAPE) is an uncommon type of non-cardiogenic pulmonary edema. Few data are available regarding ECG abnormalities in patients with HAPE. They are usually slight and related to acute pulmonary hypertension. This paper describes a case of prolonged ECG abnormalities in a subject with HAPE, with no proven cardiac diseases. The Authors discuss the pathopysiological aspects of this kind of hypoxic-induced right ventricular overload with extensive T-wave negativity in precordial leads.

Adult↗

[Orthotopic ileal neobladder: urodynamic and metabolic aspects. Our experience].

We subjected to a functional and metabolic evaluation (urodynamic examination + cystography) 10 patients underwent to radical cystectomy with a ileal orthotopic reservoir (VIP) for bladder cancer. At the moment patients have a minimum 3-years follow-up and they are out of disease. The medium capacity of the reservoir is about 447 ml, with a low pressure flow, a medium pressure of ureteral closing of 62.5 cm of H2O. At the cystography neither ureteral reflux nor post miction residuum have been proved. All the patients are continent, with the exception of one patient suffering from episodes of nocturnal enuresis. The metabolic evaluation hasn't proved substantial changes except the presence of hypocitraturia in the only patient in metabolic acidosis. In conclusion the ileal orthotopic reservoir showed a good long-term functionality without considerable complication of metabolism.

Acidosis↗