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M Patron

Publications and source records attributed to M Patron.

11 recordsLinked to original sources
PubMed1992

Polymorphous low-grade adenocarcinoma of the oral cavity: a report of 14 cases.

The clinicopathologic characteristics of 14 new cases of low-grade polymorphous adenocarcinoma of the oral cavity are presented. Tumors were located in the palate in 10 cases, and in one case each in the base of the tongue, buccal mucosa, tonsil, and retromolar pad. Nine cases were previously diagnosed as other categories of benign and malignant tumors. The tumors were classified as terminal-duct and low-grade papillary adenocarcinomas. Three cases developed local recurrence and four cases had lymph nodes metastasis, two on admission and two during the course of the disease. Two of the local recurrences and all cases with metastasis were salvaged with further surgery with or without irradiation. Recurrence and metastasis occurred only with the terminal duct adenocarcinoma. There was no death related to the neoplasm, although one patient is living with advanced disease.

Adenocarcinoma↗
PubMed1991

Glandular odontogenic cyst: clinicopathologic analysis of three cases.

The glandular odontogenic cyst is a rare cyst of odontogenic origin, first described in 1988 by Gardner et al. Three previously unreported glandular odontogenic cysts are presented; none recurred after the initial surgical treatment, and one example was associated with a squamous odontogenic tumor-like proliferation in the wall. Ten similar cases were found in the literature, and their clinical and roentgenographic features, and follow-up, have been compared with the present cases.

Adult↗
PubMed1991

AIDS-related lymphoma of the oral cavity.

Six new cases of non-Hodgkin's lymphoma (NHL), primarily located in the oral cavity, in patients infected by the human immunodeficiency virus (HIV), are presented. They all had a voluminous fungous tumoral mass, that extended from the gingiva to the buccal vestibule or palate. All were intravenous drug abusers. The diagnosis of AIDS was known in one patient, 2 patients presented with AIDS-related complex symptomatology, and in 3 cases NHL was the first manifestation of the HIV infection. All presented advanced stages (IV). Histologically, all were considered high grade NHL. It is recommended to determine the HIV status in all young patients affected with oral NHL. All intraoral lesions in AIDS patients or in patients that belong to a risk group should have a biopsy to rule out NHL or any other manifestations of AIDS.

AIDS-Related Complex↗
PubMed1991

Acinic cell carcinoma of the salivary glands. A review of 20 new cases.

Twenty patients with acinic cell carcinoma of the salivary glands are presented. Seventeen tumours were located in the parotid and three in minor salivary glands, one being considered intraosseous. According to the growth patterns, they were classified as solid-acinar in 8 patients, microcystic in 5 patients, follicular in 3 patients and papillocystic in 4 patients. 9 cases were considered high grade malignant tumours and among the 11 well-differentiated, 2 suffered dedifferentiation in local recurrences. Local recurrence appeared in 9 cases. Three cases had nodal disease on admission while 5 developed this during the course of the disease. Distant metastasis appeared in 2 cases. Local recurrence and nodal disease correlated with the degree of differentiation and state of the margins in the surgical specimen. We recommend an aggressive surgical approach followed by postoperative radiotherapy for the undifferentiated tumours and extensive ones. For the limited and better differentiated, a more limited excision, such as total parotidectomy preserving the facial nerve is suggested.

Adult↗
PubMed1991

Maxillofacial malignant peripheral nerve sheath tumours.

The clinical and pathological features of 7 patients with MPNST in the maxillofacial area are reviewed. They occurred in five men and two women; ages ranged from seven to eighty years. The parotid area and infratemporal fossa were the commonest sites (two cases each), followed by the lower lip, cheek and central mandible (one case each). Two had the antecedent of an excised neurofibroma, one with von Recklinghausen's disease and radiotherapy, that had recurred many times. Pathological slides were revised. Immunohistochemistry with S-100 protein was positive in 6 of 7 cases; electron microscopy confirmed the diagnosis in 3 cases. None showed divergent differentiation. Surgical treatment was performed in all, with or without radiotherapy. Surgical margins were positive in five cases. Recurrence took place in six and was multiple in three. Surgical salvage of the local recurrences produced satisfactory results in 3 of the 6 cases. One patient developed lung metastasis.

Adolescent↗
PubMed1990

Odontogenic ghost cell tumours. The neoplastic form of calcifying odontogenic cyst.

The tumourous form of the calcifying odontogenic cyst is a rare entity and only a small number cases have been described in the medical literature published in English. Our report concerns a 66-year-old patient with a tumourous mass in the maxilla, with clear COC histological features, in addition to an infiltrative growth pattern of the epithelial islands and ghost cells invading the subjacent stroma, oral mucosa and peripheral maxillary bone. Cytoplasmic and nuclear pleomorphism and atypical mitoses were rarely found. An aggressive surgical approach produced a satisfactory result. We have reviewed the literature available in English and compared it with our case.

Aged↗
PubMed1988

Malignant rhabdoid tumor of the tongue. A case report with immunohistochemical and ultrastructural findings.

An extrarenal malignant rhabdoid tumor of the tongue in a 10-day-old boy is described. The tumor produced severe respiratory distress and had an aggressive clinical course. The patient died 17 days after the initial diagnosis. The tumor was mostly composed of poorly differentiated, round, polygonal or elongated cells. Ultrastructural examination showed intracytoplasmic filamentous inclusions in many of the cells. The cytoplasm was diffusely positive to anti-vimentin antibodies with focal, scarce positivity to anti-keratin antibodies. To the best of our knowledge, this is the first reported case of malignant rhabdoid tumor of the oral cavity.

Cell Nucleus↗