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M Pavia

Publications and source records attributed to M Pavia.

At least 55 records · Page 3Linked to original sources

[Neurological complications during therapy with 17 MDCAA (author's transl)].

A case of a 39 years old woman on therapy with Monodicloroacetilajmaline for repetitive crises of Ventricular Tachycardia is shown. We have observed neurological symptoms by central compromission of 3rd, 4th, 6th pair of cranial nerves, cutaneous symptoms and a neurodisletic crisis. We particularly analyse the dosage of the drug in relation to the progression of symptoms and also the possible pathogenesis. Symptoms disappeared completely about 20 days after withdrawal of the drug.

Adult↗

Prevalence of hepatitis A antibodies in food handlers in Italy.

The aim of the study was to investigate the anti-HAV prevalence in food handlers in the area of Catanzaro, Italy. A cross-sectional survey was performed by selecting all food handlers attending local health units for routine medical examination during the period from May 1994 through December 1994. A prevalence of 68.7% was recorded in the 294 participating subjects, and it increased significantly with increasing age (Chi-square test for trend = 126.95; p < 0.0001). Multiple logistic regression analysis showed a significant association in the prevalence of anti-HAV with years of activity: food handlers with ten or more years' experience have an adjusted odd ratio of 2.4 (95% CI = 1.01-5.6) compared to those with a shorter period of activity. The results indicate that finding and implementing ways to motivate food handlers to use correct infection control measures routinely should be made a priority.

Adolescent↗

A seroepidemiologic survey on brucellosis antibodies in southern Italy.

This study investigated the prevalence of Brucella antibodies in the general population in two regions in southern Italy. A total of 1,294 subjects were recruited from January to June 1996 among patients attending randomly selected public and private laboratories and pediatric outpatient clinics. Information on sex, age, residence, and occupation was recorded. Seroprevalence of brucellosis was studied by the safranin O-stained antigen microagglutination test. The chi-square test and multiple logistic regression were performed. An overall prevalence of brucellosis of 3.1% was recorded; no significant difference was found between the two regions, with values of 2.7% in Campania and 3.8% in Calabria. Multiple logistic regression analysis indicated that positivity to brucellosis was significantly associated with the province the subjects reside in, ranging from 0 in Salerno to 6.2% in Caserta, and that it significantly increased with age, ranging from 1% in persons under 16 to 4.2% in those over 65 (OR = 1.7; 95% CI = 1.04-2.6), whereas it was not significantly associated with sex. When analysis was conducted after restriction to subjects reporting to be working, occupation was found not to be significantly associated with brucellosis. Since the spread of the disease is still of concern, though circulation of Brucella is decreasing, strict application of measures for the eradication of brucellosis from livestock, pasteurization of milk and dairy products, and education regarding eating habits must be pursued.

Adolescent↗

Prevalence of hepatitis E antibodies in healthy persons in southern Italy.

The aim of the study was to evaluate the seroprevalence of HEV antibodies in blood donors and in healthy persons in Calabria (Italy). An age-stratified sample of blood from donors was drawn at a regional transfusion service. Sixty persons were enrolled for each of the following age-groups: 18-20, 21-30, 41-50, 51-60, > 60 years, whereas 61 persons were enrolled in the 31-40 age-group. In the oldest age-group 38 subjects were enrolled among healthy subjects attending an outpatient clinic. Participants were invited to fill in a questionnaire, including questions on demographics, such as sex, date and place of birth, place of residence, number of people in household, and occupation; exposure to specific risk factors, such as travel in hepatitis E endemic areas; history of jaundice and/or hepatitis; drug addiction and transfusion. Results of routine serological tests for blood donation (HBsAg, HCV, HIV, ALT) were also recorded. Serum samples of subjects were stored at -80 degrees C until tested. The seroprevalence of hepatitis E antibodies was studied using in parallel two commercial ELISA tests consisting of recombinant antigens and synthetic HEV polypeptides. Three hundred sixty-one persons were recruited and six of them were positive to HEV antibodies (1.7%) by the recombinant test, whereas four were positive by the synthetic peptides test (1.1%). Overall, three subjects were positive to both tests, with a prevalence of 0.8%. Of these two (0.7%) were men and one (1.3%) a woman. As to age, two (3.3%) were in the 51-60, and one (1.7%) in the > 60 age-group. None of the positive participants had travelled to highly endemic areas, and none were positive for HBsAg or HCV. The study confirms a low circulation of the HEV virus also in southern Italy, with a prevalence of infection more similar to that of northern European countries than to that of countries of the Mediterranean basin.

Adolescent↗

[Evaluation of microbial air contamination in dental areas].

The Authors carried out a survey in dental wards in order to evaluate the qualitative and quantitative microbial contamination level of the air, which is considered a crucial habitat for the transmission of many infectious diseases. A high microbial counts were found in all of the environments tested; the microorganisms isolated belonged to pathogenous species such as Staphylococcus aureus, Staphylococcus haemoliticus, Pseudomonas aeruginosa, Acinetobacter calcoaceticus var. lwoffi. It seems necessary, therefore, to carry out preventive interventions directed to the protection of the personnel of dental care and, in particular, of the patients.

Acinetobacter↗

[Music and medicine].

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History, Ancient↗