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M Pereiro

Publications and source records attributed to M Pereiro.

At least 19 recordsLinked to original sources
PubMed2006

Study of the ITS region in an atypical isolate and comparison with six species of Microsporum.

Microsporum species are a frequent cause of cutaneous mycoses in humans. Atypical strains of Microsporum can sometimes be difficult to identify with conventional methods. Recently, we have obtained a Microsporum isolate with atypical morphology and special nutritional requirements (Microsporum CHUS-126-02). As several molecular techniques have been developed for the identification of fungi, we analysed six Microsporum species (M. canis, M. gypseum, M. gallinae, M. nanum, M. ferrugineum and M. persicolor) in order to compare them with our isolate, by using polymerase chain reaction-restriction enzyme analysis (PCR-REA). We studied the nucleotide sequence of the internal transcribed spacer regions from the nuclear DNA encoding for the ribosomal domain. Digestion with MvaI and EcoRI endonucleases obtained specific patterns for M. gypseum, M. gallinae, M. nanum and M. persicolor. Microsporum canis, M. ferrugineum and Microsporum CHUS-126-02 yielded the same patterns. Based on these results and phenotypic criteria, we classified our atypical isolate as M. canis.

Adolescent↗
PubMed2004

Cutaneous infection caused by Alternaria in patients receiving tacrolimus.

Tacrolimus, an immunosuppressant used in organ transplant surgery, is inhibitory to some medically important fungi but also may obstruct azole monotherapy in the immunocompromised patient. We observed a case of cutaneous phaeohyphomycosis caused by Alternaria alternata in a liver transplant recipient who had been under tacrolimus immunosuppression for 6 months post-transplantation. At the onset of the infection, the patient presented with an increased whole-blood tacrolimus level. After a simple surgical excision the patient was discharged from the hospital without antifungal treatment but with an adjusted tacrolimus dosage. Literature review on fungal infections in patients receiving tacrolimus suggested these patients experience cutaneous and deep mould infections that are more frequent, severe and therapy-refractory than those seen in patients with other types of immunosuppression.

Aged↗
PubMed2003

Localized granuloma annulare and autoimmune thyroiditis in adult women: a case-control study.

BACKGROUND: The coexistence of granuloma annulare (GA) and autoimmune thyroiditis (AT) has been sporadically observed in female patients, but the significance of this rarely reported association remains uncertain. OBJECTIVE: To investigate for the first time the frequency and type of thyroid disease in adult women with localized granuloma annulare (LGA) compared with a matched control group. METHODS: Twenty-four adult women with histology-proven LGA and a control group of 100 age-matched female patients with other unrelated cutaneous diseases were screened for thyroid disease in a tertiary teaching hospital in northern Spain. Laboratory evaluation included routine hematologic and chemistry analysis, antinuclear antibody, rheumatoid factor, thyroid function test (sensitive thyroid-stimulating hormone [TSH]), thyroid autoantibody levels, and antibodies to thyroid peroxidase in all patients and controls. Thyroid hormones (free triiodothyroxine and free thyroxine) were measured when TSH value was abnormal. AT was defined as hypothyroidism (TSH value >5 mU/L) and in addition to elevated antithyroid antibodies or characteristic thyroid biopsy. The results were compared using Fisher's exact test. RESULTS: Statistical evaluation of the findings obtained in this study showed mainly that the frequency of AT was increased significantly in the group of adult women with LGA (3/24, 12%) compared with the matched control group (1/100) (Fisher's exact test: P =.022). CONCLUSION: Although little can be inferred from a single investigation, the results of this pilot study indicate an association between LGA and AT in adult female patients, supporting the theory that at least a subset of GA belongs to the spectrum of autoimmune diseases.

Adult↗
PubMed2000

Case Reports. Pityriasis amiantacea as manifestation of tinea capitis due to Microsporum canis.

We report three patients, two infants and an adult, in whom their tinea capitis clinically appeared as pityriasis amiantacea. The mycological studies showed infection due to Microsporum canis in all cases. Correct diagnosis as well as adequate antimycotic chemotherapy of this atypical manifestation of tinea capitis remain a challenge to the clinician. Epidemiological aspects must be regarded also.

Adult↗
PubMed1999

Plantar hyperkeratosis due to Fusarium verticillioides in a patient with malignancy.

We report the case of an 82-year-old man with hyperkeratosis of the right sole caused by a Fusarium verticillioides infection mimicking verrucous tuberculosis; the infection was confirmed by direct potassium hydroxide microscopy, biopsy and cultures. The biopsy specimen showed an unusually deep invasion of fungal elements into the epidermis. This is an uncommon presentation in a localized cutaneous infection by Fusarium but in this case, repeated local injuries were the portal of entry initiating the process. Clinical patterns of cutaneous fusarium infections in general are also discussed.

Adenocarcinoma↗
PubMed1999

[Peritonitis following transrectal biopsy of the prostate].

OBJECTIVE: An uncommon complication of prostatic transrectal biopsy is described. METHODS/RESULTS: A case of peritonitis arising from a recto-peritoneal fistula after transrectal biopsy of the prostate is reported. The patient presented symptoms of peritonitis 15 days after undergoing ambulatory transrectal prostatic biopsy elsewhere. The imaging studies showed intraprostatic hypodense collection and peritonitis due to a recto-peritoneal fistula. The diagnosis was confirmed by laparotomy. The patient died 7 days postoperatively due to acute renal failure. CONCLUSION: Transrectal biopsy of the prostate is a simple procedure, but it is not free from serious complications.

Biopsy↗
PubMed1998

Prevalence of undetected tinea capitis in a prospective school survey in Madrid: emergence of new causative fungi.

From October 1994 to December 1996, a prospective study was undertaken in 10,000 unselected school children in Madrid, aged between 2 and 16 years (mean +/- SD 8.5 +/- 3.6 years). Fifty-two (0.52%) (including 13 immigrants from Africa) had dermatophytes in the scalp: 33 (0.33%) (including 10 immigrants from Africa) had tinea capitis and 19 were scalp carriers. Almost half of the symptomatic cases were caused by Trichophyton tonsurans (12 of 33 cases) and Microsporum canis (16 of 33 cases). T. tonsurans (13 of 19 cases) was the predominant species in the scalp carriers. Twenty-four per cent of the subjects with tinea capitis and 42% of the asymptomatic scalp carriers also had ringworm in other body sites. There was a significantly higher occurrence of tinea capitis (P < 0.001) (particularly due to T. tonsurans: P < 0.001) and of asymptomatic scalp carriers (P < 0.05) (particularly due to anthropophilic species: P < 0.01) in the immigrant population from Africa.

Adolescent↗
PubMed1997

Prevalence of undetected tinea capitis in a school survey in Spain.

From October 1994 to November 1995, a prospective study aiming to detect dermatophytes on the scalp was undertaken in 5000 unselected school children aged between 3 and 16 years (mean age 8.34 years, SD +/- 3.83). Thirty-two (0.64%) had dermatophytes in the scalp, 22. (0.44%) had tinea capitis and 10 were asymptomatic scalp carriers. It is important to point out that 33% of the patients with tinea capitis and 60% of the asymptomatic scalp carriers also had ringworm in other body sites. There was a significantly higher proportion of cases of tinea capitis (P < 0.001)(particularly due to Trichophyton tonsurans, P < 0.001) and of cases of asymptomatic scalp carriers (P < 0.05) (particularly due to Trichophyton tonsurans, P < 0.001) in the immigrant population of African origin. In all the child index cases with positive scalp cultures (tinea capitis and carriers), the household members were studied clinically and mycologically. One child had a body ringworm caused by Microsporum canis. Twelve adults had positive cultures with dermatophytosis (one tinea capitis and eleven body ringworm). Three adult patients were also carriers of dermatophytes in other body sites. Our data indicate a change in the causative agents of tinea capitis seen in Madrid over a 12-month period, with cases due to antropophilic species (T. tonsurans, T. soudanense, M. audouinii and T. violaceum) occurring in the immigrant population from Africa; as a consequence, there is an emergence of T. tonsurans in the Spanish population.

Adolescent↗
PubMed1997

Favus due to Trichophyton mentagrophytes var. quinckeanum.

We report a case of favus affecting the temporal region of the scalp in a 22-month-old boy. Mycological study of hairs and crusts identified Trichophyton mentagrophytes var. quinckeanum (T. quinckeanum), the causative agent of mouse favus. Treatment with oral griseofulvin led to healing.

Administration, Oral↗