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Biomedical subjects

M Perisić-Savić

Publications and source records attributed to M Perisić-Savić.

At least 19 recordsLinked to original sources
PubMed1994

[Leiomyosarcoma of the duodenum (case report)].

Leiomyosarcomas of the duodenum are rare tumors, usually presented with gastrointestinal bleeding and/or symptoms of duodenal obstruction, rarely with obstructive jaundice. If successfully removed, these tumors have better prognosis than carcinomas of duodenum or head of the pancreas. A 62 year old man in whom leiomyosarcoma of the duodenum was successfully removed by cephalic duodenopancreatectomy (Whipple's procedure) is presented.

Duodenal Neoplasms↗
PubMed1993

The evaluation of tumor markers levels in determination of surgical procedure in patients with gallbladder carcinoma.

In purpose of early diagnosis of gallbladder carcinoma, the serum levels of tumor markers CA 72-4, CA 19-9, CEA, AFP, Ferritin and beta HCG were determined in 124 patients with benign and malign diseases of gallbladder, before and 10 days after the operation. The most important clinical significance have CA 72-4 and CA 19-9, which are increased in Ca in situ and carcinoma of the first stage. These early stages of carcinoma cannot be diagnostified by preoperative echotomography, but radical operation is possible with recover by all means. These two tumor markers should be attended in risk group of patients for rising gallbladder carcinoma: calculosis and polyposis. The rest of tumor markers are increased in progressive carcinoma with infiltration of surrounding tissue and metastases.

Antigens, Tumor-Associated, Carbohydrate↗
PubMed1991

Retroperitoneal biloma secondary to operative common bile duct injury.

Encapsulated collections of bile ("biloma") may be a sequela of liver trauma, operative injury or disease. Such collections may be intrahepatic or extrahepatic and usually in the supramesocolic compartment of the abdomen. This is a report of a retroperitoneal biloma, an entity that has been reported only twice to date but this is the first secondary to an operative common bile duct lesion. Evacuation of the biloma and reconstruction of the associated biliary stricture were successfully carried out. The patient remains symptom free with normal clinical and laboratory data more than 14 months after surgery.

Bile↗
PubMed1991

Splenic vein thrombosis. Diagnosed with Doppler ultrasonography.

The case of a 31-year-old pregnant woman with an isolated splenic vein thrombosis, diagnosed with Doppler ultrasonography is presented. Routine ultrasound examination in the fourth month of the pregnancy revealed massive splenomegaly of unknown origin. Doppler ultrasonography subsequently revealed splenic venous thrombosis with absence of blood flow. Noteworthy gastric varices were present at the endoscopic examination. On splenectomy, a spleen weighing 2,600 was removed, and numerous venous collaterals were found in the perigastric region. The postoperative course was satisfactory, pregnancy evolved normally, and a healthy female baby was delivered at term. The patient remained in excellent health with normal clinical and laboratory data.

Adult↗
PubMed1991

[Echotomography of malignant tumors of the liver].

The echotomographic primary liver carcinoma can be hyperechogenic and hypoechogenic, or both. In metastasis, in addition to the pattern of primary carcinoma end-lesion changes are also visible, or liver parenchyma can be diffusely heterogeneous. The echotomographic findings of primary and secondary liver tumours cannot be differentiated. The origin of metastasis in the liver cannot be established by echotomography. However, a typical echotomographic picture can be obtained in some carcinoma (colon carcinoma).

Humans↗
PubMed1991

[Injury of the left hepatic vein by a large hepatic echinococcal cyst].

While different sorts of affection of the biliary tree by the hydatide cysts of the liver are frequent (20-30%), vascular complications are rare. That is why serious peroperative bleedings are usually caused by surgical mistakes. Bleeding caused by hydatide cyst itself is very rare, sudden, abundant, dramatic and usually lethal on the operative table. We present a 76-years-old man in whom during the operation of a huge hydatide liver cyst, sudden and abundant bleeding from the defect (2 x 0.5 cm) of the left hepatic vein caused by the cyst itself, appeared. The bleeding was successfully solved by direct suture of the defect. Three months later hepatitis B viral infection manifested apparently after numerous blood and plasma transfusions during surgery, and patient died in hepato-renal syndrome.

Aged↗
PubMed1990

[Diffuse adenomyomatosis of the gallbladder].

Adenomyomatosis is a rare benign proliferative disease of the gallbladder characterized by epithelial proliferation and formation of mucosal pouches through the thickened muscular layer of gall bladder wall. It appears in three different types: diffuse, segmental and localised adenomyomatosis. Diffuse type is the rarest. Etiology is unknown. Patients sometimes feel a dull pain in the upper right abdominal quadrant. Preoperative diagnosis is based on cholecystography and ultrasonography. Cholecystectomy is a method of treatment. Diagnosis is confirmed on histology. Very rarely, adenomyomatosis seems to bee a premalignant condition. We present four patients treated during the last two years, a woman and three men, 27-41 years old (average 37 years). All these patients had a dull pain in the right subcostal region, approximately 6 months before the diagnosis was established. One patient had chronic alcoholic pancreatitis with dilated pancreatic duct. Diagnosis of diffuse adenomyomatosis was made preoperatively on ultrasonography in all patients. Cholecystectomy was carried out Diagnosis was confirmed on histology. There was no carcinoma. In a patient with chronic pancreatitis Wirsungojejunostomy (Puestow) and choledochojejunostomy were also carried out.

Adenomyoma↗
PubMedDate not supplied

[Epidermoid cyst of the spleen].

A 33-year old woman with 6 x 6 cm splenic cyst of the lower pole of a moderately enlarged spleen, found during ultrasonographic examination for epigastric and left subcostal abdominal pain, is presented. At operation the spleen of 900 grams with a subcapsular cyst in pedunculated extension of the lower splenic pole, ie. accessory lobe, was removed. No other abdominal disease was found. Postoperative recovery was uneventful. Pathohistological examination revealed a cyst, 6 cm in diameter, with whitish wall filled with dark-red turbid fluid containing yellow flocules. The wall of the cyst consisted of the fibrous connective tissue with sclerotic and hyaline changes. The cyst was entirely lined by the stratified squamous epithelium, in some areas flattened, transformed into endothelium. Diagnosis of a very rare splenic epidermoid cyst in the "accessory lobe" of the lower pole, was confirmed.

Adult↗
PubMedDate not supplied

[Surgical treatment of aneurysms of the femoral artery].

The authors have presented the importance and technics of operative treatment of femoral aneurysms as the only correct method of treatment aiming at prevention of complications which are the consequence of the natural course of the disease. The majority of current operative technics involve total or partial resection of an aneurysm and reconstructive operative approach (graft interposition, bypass) aiming at establishment of the arterial continuity. In the same time the authors have emphasized the importance of echosonographic diagnostical procedure which has even some advantages over angiography, especially in cases with normal central recanalization of the clot.

Aneurysm↗
PubMedDate not supplied

[Biliary mucinous cystadenocarcinoma of the liver].

Biliary mucinous cystadenocarcinoma is an extremely rare tumour. Less than 50 cases have been reported. It is usually a multilocular cystic tumour covered with mucous producing epithelium, with papillary excrescences containing mucinous mass arising from bile ducts. The size of the tumour varies from 3.5 to 25 cm in diameter. It is more frequent in women. The majority of patients belong to the middle age population. We present a 63-year-old man who had been suffering from an epigastric and right subcostal pain of unknown aetiology for over 35 years. During the last 10 years he suffered from multiple attacks of cholangitis with high temperature, rigor, chills, pain and obstructive jaundice. Five years ago he had the attack of pancreatitis with retroperitoneal fatty necrosis for which he was operated on in another institution and cholecystectomy and pancreatic necrectomy were carried out. The attacks of cholangitis continued they were more serious and more frequent until June 1987, when the "cyst" in the left lobe of the liver, dilated bile ducts and "polyps" in the common bile duct were diagnosed by ultrasonography. During the operation advanced biliary cirrhosis, portal hypertension, splenomegaly, very dilated common bile duct full of jelly and the "cyst" in the liver filled with jelly, were found. The removal of the jelly and choledochojejunostomy resulted in temporary relief. Two months later he was reoperated for recurrent obstructive jaundice during which left lobectomy, partial excision of the cyst and cystojejunostomy between the rest of the cyst and another Roux-en-Y jejunal limb, were carried out.(ABSTRACT TRUNCATED AT 250 WORDS)

Cholestasis↗
PubMedDate not supplied

[Tuberculosis of the lymph nodes and spleen preceding Hodgkin's disease].

Tuberculosis of the lymph nodes is not rare today. However tuberculosis of the spleen has been very rare even in the past when many patients had suffered from tuberculosis. The appearance of Hodgkin's disease following tuberculosis is an extremely rare condition. It has thought that deficiency of cellular immunity was responsible for both tuberculosis and malignancy. We present a 44-year-old man in whom lymph node and spleen tuberculosis antedated the clinical onset of Hodgkin's disease for three years. The patient was successfully treated with tuberculostatics until he developed Hodgkin's disease; he was treated according to MOPP protocol. Six years after the onset of disease nodular lesion of the spleen was detected and splenectomy was carried out. The enlarged spleen, g in weight, was removed with tuberculoma in the lower pole, 4 cm in diameter. The tuberculostatic therapy for a year followed splenectomy. The patient stayed symptom-free, with no sign of tuberculosis. He is in the remission stage of Hodgkin's disease with normal clinical and laboratory data.

Adult↗