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Biomedical subjects

M Perrin-Fayolle

Publications and source records attributed to M Perrin-Fayolle.

At least 109 records · Page 6Linked to original sources
PubMed1980

[Respiratory functional tests in professional asthma. Value of realistic tests (author's transl)].

The diagnosis of professional asthma raises problems that cannot be solved in many cases either by anamnestic data or by skin tests: realistic can then prove very useful. Reproducing in the laboratory the professional surroundings, these tests consist in studying the ventilatory variations induced by allergens inhaled during work. The authors report the results of these examinations done on 30 patients whose realistic tests were performed with controls of ventilatory variations by body plethysmography. Confirming the professional etiology of asthma was reached 16 times out of 30 by these tests. These substances concern: chemical products (9 cases), dust of plant or animal origin (4 cases), various saw dusts (2 cases), tissue extracts (1 case). These results enabled the authors to underline the interest of these tests which nevertheless have limits: a negative realistic test is not enough to eliminate this diagnosis, because it is not always possible to reproduce exactly the workshop atmosphere in the laboratory. On the contrary, a positive test does not necessarily mean that the asthma is truly and predominantly a professional asthma. Results must therefore always be interpreted in relation with the clinical context, although the mechanism involved is known to be variable. A positivity can be attributed to an allergic mechanism, a non immunological release of mediators, or simple irritative reactions. In spite of these draw-backs, realistic tests represent one of the best means of diagnosing professional asthma.

Acetylcholine↗
PubMed1980

[A thoracic "stealing" vascular syndrome (author's transl)].

The authors report quite a remarkable observation of a thoracic "stealing" vascular syndrome, apparently a sequela of a previous pleural involvement. It was a patient with fainting fits in effort related to severe hemo-diversion of the sub-pleural vascular laci fed by several vascular pedicles coming from the internal mammary artery and several broncho-intercostal arterial vessels. Selective bronchial arteriography revealed these pedicles, enabling an important blood derivation in effort without corresponding venous return, with a phenomenon of low cerebral outflow; a series of embolisms in these pedicles enabled to obtain a valuable obliteration of the main ones with a complete disappearance of the clinical signs. The syndrome mentioned in this observation is related to the "stealing" vascular ones described in the level of the subclavian artery.

Brain Ischemia↗
PubMed1980

[Is there a pleural involvement in bird-breeder alveolitis? (author's transl)].

The authors report the observation of a bird-breeder lung in which the first sign was a pleural involvement, as the serosa biopsy revealed lymphoplasmocytic inflammatory infiltrates, lesions compatible with this interpretation. No such observation was found in the literature. The true incidence of these eventual pleural involvements during these allergic diseases remains to be evaluated as well as their etiopathogenic determinism.

Adult↗
PubMed1980

[Complications with rifampicin treatment: one case with anuria (author's transl)].

The authors report a new case of acute renal insufficiency with Rifampicin. They evoke the clinical background which is characteristic of these anuric tubular nephritis. They recall the different complications with Rifampicin to which they can be associated and the different mechanisms which can be at the origin of this affection as well as the difficulties to reveal them. Then, they insist on the prevention of renal accidents within the frame of our present knowledge.

Acute Kidney Injury↗
PubMed1979

[Value of lymphoblastic transformation test for diagnosis and treatment of microbial asthmas in adults (author's transl)].

A lymphoblastic transformation test (LTT) done on 9 germs in 30 patients (270 tests) with bacterial asthma was found positive 117 times out of 170 (43.3%) while the same study done on a control group of 100 non microbial asthma was generally negative (5% of positive responses). Positive LTT confirmed, in 59.2% of cases, the cutaneous tests. In the other cases, discrepancies can be found in both ways: positive LTT and negative cutaneous tests (16.9%) or the reverse (23.9%). The significance of disagreeing results is discussed. Specific desensitizations done only with the bacteria producing agreeing positive reactions, gave interesting though inconstant results.

Adult↗
PubMed1979

[Bronchial cytology of "occult" lung cancers (author's transl)].

Having underlined the value of bronchial cytology for the early diagnosis of lung cancers, the authors report 7 observations concerning a particular clinical form: the "occult" lung cancer with a malignant cytological precession more or less in advance in relation with the radiological or fibroscopical data. Malignant cells can be found in sputum from 9 months to 8 years beforehand. All histological types can be seen but no cancer of the anaplasic type with small cells was identified either in this series or in the literature. The authors insist also on the difficulty in localizing these cancers in situ at a very early stage. They set apart the insufficiencies of the X-ray results in several observations and the limits of other investigating techniques (bronchography, scintigraphy, echotomography, ...). These tumours seem to have a mild evolutivity.

Aged↗