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Biomedical subjects

M Personne

Publications and source records attributed to M Personne.

16 recordsLinked to original sources
PubMed1999

[Serious effects of chloroquine overdose. Prescribe the smallest possible dosage-packages and inform about the risks].

An increasing number of acute overdoses with chloroquine has been reported in Sweden--some with fatal outcome. This substance is clearly one of the most toxic pharmaceuticals on the Swedish market. Four cases are described. Travelling to the tropics has become very popular, and chloroquine is often given as a prophylactic antimalarial. This inexpensive drug is often prescribed in 100-tablet packages, and any surplus is often stored in the home. Awareness of toxicity is low among users and doctors in this country. Preventive measures are suggested.

Adolescent↗
PubMed1998

[Risk of lung damage found in fire-eaters. Twelve Swedish hospital cases reported].

Twelve hospital cases and 69 telephone enquiries relating to fire-eating have been registered at the Swedish Poison Information Centre. Chemical pneumonitis with symptoms such as coughing, fever, dyspnoea and hypoxia is common after petroleum distillate ingestion with concomitant aspiration. Pleuritic chest pain is an additional characteristic symptom among fire-eaters. Pulmonary infiltrates and pleural effusions are also frequent findings.

Adolescent↗
PubMed1998

[The rattlesnake is not more dangerous than the viper].

The article consists of a comparison of the effects of snakebites inflicted by North American rattlesnakes and those of European vipers, based on a review of series of snake bite victims reported in the literature since 1980. The two groups of snakebites were found to manifest close similarity, even regarding the currently low fatality rates. Whereas local reactions seem to be more extensive after rattlesnake bites, circulatory symptoms including severe hypotension appear to be more common after viper bites. It is concluded that the two groups of snakes may be regarded as equally dangerous.

Animals↗
PubMed1997

Citalopram overdose--review of cases treated in Swedish hospitals.

BACKGROUND: The toxic effects of acute citalopram overdose are reported by the Swedish Poisons Information Centre. DESIGN: Case reports received from Swedish hospitals during 1995 have been analyzed. Forty-four cases of pure citalopram intoxication have been studied in detail. RESULTS: At doses below 600 mg, mild symptoms were observed. Doses above 600 mg caused ECG abnormalities and convulsions in some patients, while doses greater than 1900 mg caused such symptoms in all patients. CONCLUSIONS: The findings are consistent with previous reports claiming that selective serotonin reuptake inhibitors are less toxic compared to tricyclic antidepressants. However, there is a risk of developing serious symptoms when large doses have been ingested.

Adolescent↗
PubMed1985

High-dose prenalterol in beta-blockade intoxication.

This study presents a case of beta-blocker intoxication due to massive overdose of metoprolol (7.5 g). Prenalterol in a dose of 420 mg was given as antidote, in combination with epinephrine in intermittent doses. Resuscitation was performed during 4 hours because of mechanical asystole. The patient regained health in 24 hours after further repeated doses of 30 mg prenalterol. Prenalterol is valuable in the management of toxic doses of beta-blocking drugs, and a titration to extremely high doses of prenalterol might be necessary.

Adult↗