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Biomedical subjects

M Petran

Publications and source records attributed to M Petran.

4 recordsLinked to original sources

Association between bronchial hyper-reactivity and exposure to silicon carbide.

A clinical study of 191 workers in the silicon carbide production industry was carried out in order to determine the prevalence of respiratory symptoms (wheezing, dyspnoea and breathlessness after exercise). Such symptoms occurred in 50 (26.1%) subjects, of whom 24 accepted testing for bronchial reactivity. Of these 24, 19 (79.2%) were positive. These findings suggest that exposure to SiC may be associated with bronchial hyper-reactivity. Positive results were more frequent in women than in men, while differences between smokers and non-smokers were insignificant, a phenomenon that has often been noted in persons exposed to massive risk.

Adult↗

Tandem scanning reflected light microscopy of internal features in whole bone and tooth samples.

An improved version of the tandem-scanning reflected-light microscope (Petran et al., 1968) has been studied with respect to its applicability to the study of mammalian mineralized tissues. It was found to have important advantages compared with other light microscopic methods, since it allowed microscopic structures to be seen at considerable depths within intact specimens. It has a small depth of focus and gives high contrast for features such as osteocyte lacunae and canaliculi in bone, and prism boundaries in dental enamel.

Animals↗

[Radiological observations in relation to occupational exposure to silicon carbide (SiC)].

There have been investigated radiologically 191 workers from a SiC factory, exposed to dust concentrations exceeding largely that TLV and with a content of non-reactive SiO2 less than 1%. Radiological examinations were performed systematically at a three years interval, beginning with 1988. Radiology interpreting was performed according to ILO 1980 classification for persistent radiological opacities due to mineral dusts. Our results sustain the idea of the pneumoconiogen potential of SiC: there is a high prevalence of radiological findings (16.2%) and the opacities have an extend from 2 to 6 areas and the profusion from 0/1 to 2/2.

Air Pollutants, Occupational↗