COMPT, a time-sharing program for nonlinear regression analysis of compartmental models of drug distribution.
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Animals↗
Biomedical subjects
M Pfeffer
Publications and source records attributed to M Pfeffer.
Narcotic and narcotic antagonist analgesics: their effect on rat brain monoamine oxidase in vitro.
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Analgesics↗
Metabolism and pharmacokinetics of naloxone.
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Administration, Oral↗
Intestinal sorption of anisotropine methylbromide in the rat.
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Animals↗
Effects of ouabain on cardiac output and pulmonary blood flow in dogs.
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Animals↗
Metabolites of naloxone in human urine.
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Chromatography↗
Rapid procedure for liquid scintillation counting of animal tissues using a nitric acid digestion procedure and a dioxane-based scintillator.
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Carbon Isotopes↗
Rat brain monoamine oxidase inhibition by beta-diethylaminoethyl diphenylprophylacetate (SKF-525A).
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Animals↗
Human urinary excretion of orally administered anisotropine methylbromide.
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Biological Assay↗
Human urinary excretion of the quaternary ammonium compounds anisotropine methylbromide and propantheline bromide.
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Humans↗
Psychopharmacological profile of molindone.
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5-Hydroxytryptophan↗
Beta-cyanoalanine, an inhibitor of rat liver cystathionase.
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Alanine↗
Metabolism of beta-cyanoalanine.
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Alanine↗
Gamma variate fits to pharmacokinetic data.
The gamma variate, C = Ataexp(-bt), was tested, as a fitting function, with various real and error-free simulated intravascular and extravascular pharmacokinetic data sets and the results compared with polyexponential fits. For extravascular data, the gamma variate is only suitable to globally fit data which might otherwise be described biexponentially. For intravascular data, the gamma variate could only fit a limited range of the possible concentration-time profiles. Gamma variate fitting algorithms must minimize relative deviations; fits using unweighted sums of squared deviations gave excellent results at higher concentration values but consistently underestimated terminal descending portions of the data.
Analysis of Variance↗
Genetic evidence of Dobrava virus in Apodemus agrarius in Hungary.
Using nested polymerase chain reaction, we sequenced Dobrava virus (DOB) from the rodent Apodemus agrarius in Hungary. The samples we isolated group with DOB samples previously isolated from A. flavicollis. This grouping may indicate host switching.
Animals↗