[Insulin resistance in female patients with hirsutism].
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Blood Glucose↗
Biomedical subjects
M Pjević
Publications and source records attributed to M Pjević.
[The effect of synthetic gonadotropin releasing hormone on the plasma levels of FH and LSH in women with hirsutism and polycystic ovaries].
GN-RH test was performed in 33 women with hirsutism and irregular menstrual cycles. Fourteen patients had polycystic ovary syndrome (PCO) and 19 had idiopathic hirsutism (IH). In the control group, there were 5 healthy women with regular menstrual cycles. Absolute cumulative increase of LH as significantly higher in the examinees with hirsutism than in the control group. A significantly higher net increase of LH was found only in the PCO group. However, absolute and net increase of FSH in examinees with hirsutism did not significantly differ from that in the control group. Patients with PCO had a significantly higher increase of FSH than the IH group. Only the PCO group had a significant correlation between basal LH and LH increase during the test. It was found that patients with hirsutism and irregular menstrual cycles had an increased reactivity of the hypophysis to a direct stimulation with synthetic GN-RH. The degree of disfunction of the gonad axis in women with PCO is significantly higher than in patients with IH.
Adult↗
[Infertility and endometriosis].
The goal of this study was to set the relation between infertility and endometriosis. It included 500 infertile female patients who underwent laparoscopy in order to find out the cause of infertility. The prevalence of endometriosis in these patients was 26%, that is significantly higher than in the control group which consisted of 200 randomly chosen fertile women in whom prevalence of endometriosis was 5%. Patients with endometriosis mainly belong to the group of 25-29 years of age with a median duration of infertility of 2-4 years. Endometriosis occurs three times more often in the group of patients with primary sterility than in patients with secondary sterility. Majority of patients (71.5%) are with minimal or mild endometriosis.
Adult↗
[Regional technics for postoperative analgesia].
Postoperative analgesia has been neglected for a long time, whereas postoperative pain has been considered inevitable cost of operations. Postoperative pain causes not only subjective difficulties, but as a stress factor affects functions of the autonomous and endocrine system, which may cause a number of disorders after the surgery. Advances in anesthesiology have contributed to increased role of anesthesiologists in application of regional techniques for postoperative pain. This paper describes regional techniques for postoperative analgesia: epidural, spinal analgesia, intercostal, paravertebral, interpleural, plexus blockade, peripheral nerve blockade and infiltrative local analgesia. Advantages and disadvantages of these techniques in regard to traditional method of parenteral analgesia in the postoperative period have been pointed out. Application of regional analgesia is recommended before the surgery, because it prolongs the time when analgesia is needed for the first time and decreases both pain and postoperative analgesia.
Analgesia↗