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Biomedical subjects

M Plant

Publications and source records attributed to M Plant.

8 recordsLinked to original sources

Lipid and lipoprotein (a) concentrations in renal transplant patients.

Lipid and lipoprotein concentrations, including lipoprotein (a), were measured in 67 clinically stable renal allograft recipients and compared with age- and sex-matched controls. Median lipoprotein (a) concentrations were significantly elevated in the transplant group (P = 0.048), with the distribution of apoprotein (a) isoforms being similar between the two groups. The transplant group also demonstrated significant elevations in cholesterol (P less than 0.0001), triglycerides (P = 0.0007) and low-density lipoprotein cholesterol (P less than 0.0001). There was no significant difference in high-density lipoprotein cholesterol concentrations between the groups although there was the expected tendency for higher values in females. Lipoprotein abnormalities are common following renal transplantation and these patients also demonstrate elevated lipoprotein (a) values. This unique lipoprotein is known to be atherogenic and may contribute to the development of vascular disease, which is a common mode of death in these patients.

Adolescent

Licit and illicit drug initiations and alcohol-related problems amongst illicit drug users in Edinburgh.

A non-random study group of one hundred and fifteen regular illicit drug users were interviewed in Edinburgh between January and July 1988. It was found that initiation to the use of alcohol and tobacco generally preceded the first use of illicit substances. The circumstances of initiation to alcohol use often differed from those of initiation to an illicit substance. Results from the first phase of this longitudinal study also indicate that the majority of current users of illicit drugs have experienced a wide range of problems attributed to alcohol consumption. Opiate users in particular, reported experiencing alcohol-related trouble with the police, being involved in alcohol-related violence and being banned from premises due to their drinking.

Adult

Alcohol, drugs and AIDS-related risks: results from a prospective study.

This paper examines the relationship between AIDS-related risks amongst a cohort of young adults and alcohol, tobacco and illicit drug use. Data were elicited by standardized interview and self completed questionnaires from a non-random study group of 350 males and 428 females. Only a minority of respondents reported always using condoms during sexual activity. Over half the study group reported having had only one sexual partner in the past year. Levels of condom use were not significantly associated with general levels of alcohol-consumption or alcohol-related consequences. Experience of alcohol-related consequences by both males and females was associated with the perceived risk of their sexual behaviour. Respondents who reported a high frequency of combining alcohol and sex were seven times less likely than others to report always using condoms for vaginal intercourse.

Acquired Immunodeficiency Syndrome

Young people and drinking: results of an English national survey.

An account is presented of a survey of self-reported drinking habits and beliefs about alcohol amongst a national sample of teenagers in England. Fieldwork was conducted during 1988 and 1989 and involved 27 systematically selected state secondary (high) schools. Respondents were virtually all aged 14-16. The majority of teenagers reported drinking only moderate amounts of alcohol. Even so, a third of the males and nearly a fifth of the females reported having at some time consumed the equivalent of five and a half pints of beer on a single occasion. Factual knowledge about alcohol was not high and more than half of the study group supported a reduction in the legal minimum age at which alcohol may be purchased in licensed premises.

Adolescent

Drug problems and patterns of service use amongst illicit drug users in Edinburgh.

Some results are presented from a continuing prospective study of patterns of illicit drug use in the community. A study group of 115 illicit drug users in Edinburgh were contacted by a non-random method known as 'snowballing'. These were interviewed using a standardized schedule that related to over 200 variables. The use of drugs services are discussed and it is noted that reasons for making contact with such services are complex and not directly associated with any one factor. Extent of illicit substance use and adverse consequences experienced as a result of illicit substance use, are seen to be associated with agency contact, although it is suggested that many other reasons such as social pressure have a role to play. Some individuals, including opiate users, reported that their drug use had not led to any adverse consequences, others had experienced a variety of adverse consequences yet had had no contact with a drugs agency. The implications of these results are discussed.

Adult

The first symptoms of carcinoma of the oesophagus, with particular reference to amaqhakuva. A report from the Republic of Transkei.

The first symptoms of cancer of the oesophagus in 82 Xhosa patients were found to be dysphagia (43%), interscapular back pain (23%), sore throat (21%) and epigastric pain (11%). More than half of the patients in whom a sore throat was the first symptom of the disease described the simultaneous occurrence of oropharyngeal lesions (amaqhakuva). No correlation could be found between the first symptoms and the characteristics of the oesophageal carcinoma at the time of presentation.

Abdomen

Drinking careers.

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Alcoholism