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M Pollack

Publications and source records attributed to M Pollack.

At least 109 records · Page 6Linked to original sources

Improved direct colorimetric method for the determination of total serum globulins.

1. A direct, fast, and efficient manual method is described for determining total serum globulins. The procedure is based on the reaction of tryptophan residues with glyoxylic acid in the presence of an oxidizing agent to produce a highly colored 4-carboline derivative. 2. A single, odorless reagent is employed and Beer's law is obeyed up to at least 7 g/100 ml of globulin at 565 nm. 3. Results of parallel assays demonstrate good agreement between our method and a reference cellulose acetate electrophoretic method and poor agreement with a HABA dye binding method.

Azo Compounds

Alpha Fetoprotein: An index of progression or regression of hepatoma, and a target for immunotherapy.

CLINICAL AND LABORATORY STUDIES OF AFP PRODUCING HEPATOMAS DEMONSTRATED THAT: 1) serum AFP levels correlated directly with tumor growth; 2) circulating AFP could be cleared by passive administration of an. excess of anti-AFP; and 3) highly specific anti-AFP functioned as a carrier to localize diagnostic and possibly therapeutic amounts of radioactivity in hepatoma tissue. These studies helped elucidate certain criteria which should be fulfilled before attempts to initiate passive humoral immunotherapy of cancer are undertaken.

Alpha-Globulins