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M Pozzi

Publications and source records attributed to M Pozzi.

102 records · Page 6Linked to original sources
PubMedDate not supplied

[Treatment of pure stage one ovarian dysgerminoma in young women. Report of a case and review of the literature].

The authors report a case of stage 1 ovarian dysgerminoma (OD) in a young woman aged 23 who subsequently underwent conservative surgery. A review of the literature shows that in 80% of cases this neoplasia is present at stage 1A and 85% of patients are under 30, with a 5-year survival rate of 95%. OD treatment should therefore be personalized and, although it continues to be controversial, most authors agree that in young women in whom the disease is limited to one ovary, without lymph node metastases, treatment can be restricted to monolateral adnexectomy, thus assuring the patient's future fertility.

Adult↗
PubMedDate not supplied

[Urea distribution volume and ionic dialysance].

PURPOSE: Direct dialysis quantification (DDQ) represents the gold standard for determining urea distribution volume (V) in hemodialysis (HD) patients, but is impractical for routine use because it requires equilibrated post-dialysis plasma water urea concentration. The "formal" single-pool, variable volume, urea kinetic model (SPVV-UKM) is easier to use, needing a blood sample drawn immediately after the dialytic session, but to obtain a V value consistent with the DDQ method, it requires a correct estimate of dialyzer urea clearance (Kd), actually often overestimated. Ionic dialysance (ID) accurately estimates the "effective" urea clearance (Keff), namely Kd corrected for total recirculation. Using ID as an input parameter to SPVV-UKM, correct V values are expected when end-dialysis plasma water urea concentrations are determined in a blood sample drawn after the blood pump speed has been reduced to 50 ml/min for 2 min (Upwt2'). OBJECTIVE: We aimed to compare the V values determined by SPVV-UKM, ID and Upwt2' (VID), those determined by "formal" SPVV-UKM (VKd) and those determined by the anthropometric method proposed by Watson (VA), with the V values determined by the gold standard DDQ method (VDDQ). METHODS: Thirty-one anuric patients on chronic thrice-weekly HD were studied in 31 dialysis sessions (one per patient). RESULTS: VDDQ = 26.5 +/- 5.3 L; VID = 26.2 +/- 5.1 L; VKd = 32.1 +/- 5.7 L;. VA = 33.2 +/- 5.8 L. The mean (VID - VDDQ) difference was -0.2 +/- 1.3 L, not statistically significant (95% confidence interval (95% CI) -0.7 to 0.2 L; p=0.302); the mean (VKd - VDDQ) difference was 5.6 +/- 2.3 L, statistically significant (95% CI 4.7 to 6.4 L; p<0.001); the mean (VA - VDDQ) difference was 6.7 +/- 2.7 L, statistically significant (95% CI 5.7 to 7.7 L; p<0.001). CONCLUSIONS: ID use as an input parameter to SPVV-UKM allows adequate V determinations and, at the same time, circumvents the problem of delayed post-dialysis blood samples. On the other hand, the use of "formal" SPVV-UKM or of anthropometric equations leads to a significant overestimation in urea distribution volume.

Anuria↗
PubMedDate not supplied

[Ionic dialysance: which relationship with effective urea clearance?].

PURPOSE: It has been suggested that ionic dialysance (ID) can adequately estimate the "effective" urea clearance (eK), i.e. urea clearance corrected for total (access and cardiopulmonary) recirculation. Unfortunately, the results obtained by different authors in determining the relationship existing in vivo between ID and eK do not always agree. Furthermore, it has been recently evidenced that ID values could be different, according to the different methods used to modify the inlet dialysate conductivity during ID measurement. OBJECTIVE: We aimed to verify the relationship between the mean values of repeated instantaneous ID determinations and the urea clearance values corrected for access recirculation, urea clearance corrected for total recirculation (eK) and urea clearance corrected for both total recirculation and post-dialysis urea rebound (body urea clearance), determined according to the direct quantification method (dKDDQ, eKDDQ and bK, respectively). METHODS: Thirty-one anuric patients on chronic thrice-weekly hemodialysis (HD) were studied in 31 dialysis sessions (one per patient), performed using Integra machines equipped with the Diascan module for the automatic ID determination and the Quantiscan module for the fractional collection of outlet dialysate. The mean values of repeated ID determinations at 30 min intervals throughout each dialytic session by the Diascan module were compared with dKDDQ, eKDDQ and bK values. RESULTS: ID = 179 +/- 24 mL/min; dKDDQ = 200 +/- 27 mL/min; eKDDQ = 188 +/- 26 mL/min; bK = 165 +/- 25 mL/min. The mean (ID - dKDDQ) difference was -21 +/- 10 mL/min (95% confidence interval (95% CI) -25 to -17 mL/min; p<0.001). The mean ID/dKDDQ ratio was 0.90 +/- 0.05, indicating a mean difference between dKDDQ and ID of 10%. The mean (ID - eKDDQ) difference was -9 +/- 9 mL/min (95% CI -12 to -6 mL/min; p<0.001). The mean ID/eKDDQ ratio was 0.96 +/- 0.05; therefore, indicating a mean difference between eKDDQ and ID of only 4%. The mean (ID - bK) difference was 15 +/- 7 mL/min (95% CI 13 to 17 mL/min; p<0.001). The mean ID/bK ratio was 1.09 +/- 0.05, indicating a mean difference between bK and ID of 9%. CONCLUSIONS: The mean value of repeated ID determinations could be considered clinically as an adequate estimate of urea clearance corrected for total recirculation (eKDDQ). Given that ID determination does not require either blood sampling or laboratory tests, therefore, it becomes possible to estimate easily and rapidly, once the urea distribution volume (V) has been correctly determined, the Kt/Vsp at each dialytic session.

Anuria↗
PubMedDate not supplied

Dysphagia due to anterior cervical osteophyte. Case report.

A case of 61-year-old man with a 2-year history of progressive difficulty in swallowing solid foods is presented. CT-scan and barium swallow test demonstrated an anterior osteophyte at C6. Resection of the osteophyte resolved the dysphagia. The rarity in the neurosurgical literature, the pathogenesis and the management of this condition are discussed.

Deglutition Disorders↗
PubMedDate not supplied

Drainage of Aspergillus "primitive" brain abscess with long-term survival. Case report.

Aspergillus species are second only to Candidosis as the most common cause of fungal infections of the central nervous system in immunocompromised patients. Very rare is the sole abscessual cerebral localization in nonimmunocompromised patients. Successful treatment of Aspergillus brain abscess has been reported only few times. A case of Aspergillus "primitive" brain abscess treated by surgical therapy associated with local and general mirated antifungal therapy is described. The long-term survival with complete clinical and radiological recovery is reported.

Adult↗
PubMedDate not supplied

[Usefulness of the integration between the values of the 1-hour blood xylose test and the hydrogen breath-test after xylose oral load for the indirect evaluation of mucosa damage].

Considering 50 children affected by sub-acute gastrointestinal diseases by severe growth disorders, we have compared the "one-hour blood xylose test" with the "xylose and lactose H2 breath test, looking for a relationship with the duodeno-jejunal mucosal damage. Finally the integration between the "one hour blood xylose test" and the "xylose H2 breath test" may be useful in order to compare more exactly the results of both xylose tests with the mucosal damage. Lactose H2 breath test seems less reliable for our purposes because of the possible presence of children with lactase deficiences, hardly comparable with the mucosal damage.

Breath Tests↗
PubMedDate not supplied

[The value of the Pap test in the diagnostic approach to HPV infection of the cervix uteri].

HPV infection of the low genital tract is the most diffuse STD world wide. For this reason it's necessary to follow a simple flow chart to reach a correct diagnosis and to practice an adequate therapy. The authors relate on their experience in the management of a group of patients they have observed in a STD clinic. In this group it was executed a diagnostic protocol including Pap test, in situ hybridization, dot blot and histologic examination on tissue biopsies. From the analysis of the obtained data, the authors state that the Pap test is very useful to start in the diagnostic protocol, for it is precise, inexpensive and allows to identify the patients to follow with further diagnostic procedures such as colposcopy and histologic examination, in order to reach an exhaustive diagnosis and to assess the proper therapy.

Adult↗
PubMedDate not supplied

Sporadic generalized lentiginosis without systemic involvement.

A 42-year old Caucasian man with generalized, acquired lentiginosis and no other associated diseases is described. A brief discussion about the significance of the term lentiginoses, the problems of their classification and nomenclature is also presented. The presence at the histopathologic examination, of some junctional nests of melanocytes provides the basis for a discussion of the relationship of the case presented, as well as other lentiginoses, with melanocytic naevi.

Adult↗