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Biomedical subjects

M Pradeep

Publications and source records attributed to M Pradeep.

2 recordsLinked to original sources

Deterioration of theatre discipline during total joint replacement--have theatre protocols been abandoned?

The results of the Medical Research Council trial by Lidwell et al. in 1982 [Lidwell OM, Lowbury EJ, Whyte W et al. Effect of ultraclean air in operating rooms on deep sepsis in the joint after total hip or knee replacement: a randomised study. BMJ 1982; 285: 10-4] showed a decrease in infection rates following joint replacements carried out in ultraclean air theatres. Since then, the orthopaedic community in the UK has relied to a large extent on laminar airflow theatres to control infection following arthroplasty. At the same time, there has been a decline in the emphasis on basic principles and practices of antisepsis based on scientific evidence. We undertook this audit to establish whether published recommendations on theatre discipline were being followed in operating theatres where joint replacements are carried out, in England, Scotland and Wales. Our results show that with improvement in technology involved in clean air theatres, and availability in practice, slackness has crept into theatre protocol. In view of the fact that infection following arthroplasty has not been eliminated or indeed in some cases, maintained at the levels of the Medical Research Council study, we feel that traditional practices should be reintroduced. This study shows that there is pressing need for a set of recommendations on theatre practice for all staff in operating theatres that carry out joint replacements.

Air Microbiology↗

Perinatal mortality--a hospital based study.

A total of 5082 consecutive deliveries in Medical College Hospital, Kottayam during the period August 1992 to July 1993 constituted the study. Perinatal mortality rate (PMR) was 38.5 per 1000 total births and autopsy rate was 72%. More than 85% of perinatal deaths occured in low birth weight and preterm babies. Perinatal hypoxia and congenital anomalies were the leading causes in late fetal deaths (LFD). The main causes of early neonatal deaths (END) were perinatal hypoxia, infections, congenital anomalies and hyaline membrane disease (HMD).

Developing Countries↗