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M Prazić

Publications and source records attributed to M Prazić.

15 recordsLinked to original sources

The clinical use of human leukocyte interferon in viral infections.

This review presents the results of the clinical use of human leukocyte interferon (HLI) in certain diseases with viral etiology. Viral infections with manifestations in the eye, skin, and/or mucous membranes and in the respiratory system were treated with HLI by local application. HLI was incorporated into ointment, oil suspension, powder, dilution for inhalation, and dilution for subcutaneous and subconjunctival injections. The treatment in some of the diseases yielded statistical results that were highly significant in favor of interferon.

Adolescent↗

Ototoxicity with children caused by streptomycin.

In the hospital for pulmonary tuberculosis in children, a group of 975 children treated with streptomycin sulphate was audiologically examined and in 36% of children ototoxic lesions were defined. From these, in 24% the damage affected only the vestibular labyrinth, in 8% both the vestibular labyrinth and the organ of Corti and in 4% the organ of Corti alone.

Adolescent↗

[Rapid differentiation between bacterial and atypical pneumonia in children].

We examined 116 children aged 3-7 years who were hospitalized in our Clinic during the period of one year. We observed certain clinical and laboratory parameters connected with chest X-rays. These parameters were necessary for fast distinguishing between bacterial and atypical pneumonia, in order to initiate an adequate antimicrobial therapy. The most important laboratory parameter for a fast diagnosis is CRP (reactant of acute phase of inflammation, which increases as soon as 6 to 12 hours from the beginning of the illness), and also important is: leukocyte count together with neutrophilia in differential count, which is also shown in our article. Erythrocyte sedimentation rate was moderately elevated in both bacterial and atypical pneumonia. However, the values were moderately higher in cases of bacterial pneumonia, especially in children who were hospitalized between the 2nd and the 5th day of the illness. Nevertheless, there was no correlation between the erythrocyte sedimentation rate and the type of the illness in children who were hospitalized on the first day of the illness. We conclude that CRP was the most useful parameter in fast distinguishing bacterial from atypical pneumonia.

Child↗