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Biomedical subjects

M Prcović

Publications and source records attributed to M Prcović.

At least 19 recordsLinked to original sources
PubMed1993

Pulmonary venous flow pattern studied by transoesophageal pulsed Doppler echocardiography in mitral stenosis in sinus rhythm: effect of atrial systole.

In 13 patients with isolated mitral stenosis in sinus rhythm the pulmonary venous flow was evaluated by transoesophageal pulsed Doppler echocardiography. The patients were divided into two groups according to their mitral valve area (MVA); Group I (MVA < 1.5 cm2, n = 7 patients); and Group II (MVA > 1.5 cm2, n = 6). The patients in group I with haemodynamically significant mitral stenosis had lower velocities of systolic (S), diastolic (D) and atrial retrograde (A) waves of pulmonary venous flow (PVF) compared to milder stenosis (P < 0.05). The peak velocity of pulmonary retrograde venous flow at atrial contraction (A) primarily depends on the relative amplitude of the atrial transmitral wave (RA), which is measured from the onset of atrial systole to its peak velocity. We found a highly positive correlation between RA of mitral valve flow (MVF) and A wave of PVF (r = 0.87, P < 0.0001). There was also a highly negative correlation (r = 0.80, P < 0.001) between A of PVF and ratio of early (PE) to late (PA) velocities of MVF. Therefore, the retrograde A wave of PVF is related to the pressure generated in the left atrium during atrial systole. Use of pulmonary vein velocities in conjunction with mitral flow velocities can increase our understanding of the haemodynamics of mitral stenosis and provide a new insight into left atrial performance.

Adult↗
PubMedDate not supplied

Bidirectional shunt flow across a ventricular septal defect: pulsed Doppler echocardiographic analysis.

Pulsed Doppler echocardiographic and hemodynamic examinations were performed in 31 patients (mean age 17.8 years) with isolated ventricular septal defect (VSD). Three groups were studied: group I (n = 6) patients had severe pulmonary vascular obstructive disease (PVOD); group II (n = 12) patients had pulmonary hypertension (PH) without severe PVOD; group III (n = 13) patients had no PH. Bidirectional shunting was detected in 9 VSD patients (6 in group I and 3 in group II). Patients with low to moderately elevated right ventricular pressures demonstrated left-to-right shunting across the defect throughout the cardiac cycle. When systolic pressure in the right ventricle reached approximately 60% of the left ventricular pressure, right-to-left shunting occurred across the defect during early and mid diastole. However, in patients with Eisenmenger syndrome (group I) the right-to-left shunting occurred during late systole with continuation during the early and mid diastolic period. The earlier occurrence of right-to-left shunting (index < 0.5 second) signifies the presence of severe PVOD.

Adolescent↗
PubMedDate not supplied

Use of continuous wave Doppler echocardiography to evaluate the hemodynamic importance of atrial systole in patients with mitral stenosis.

Continuous wave Doppler echocardiography was used to assess the hemodynamic role of left atrial systole and its effect on left ventricular performance in 31 patients with isolated mitral stenosis. Fourteen of the patients had mild stenosis, whereas the remaining 17 had severe stenosis. The contribution of atrial systole to the cardiac output was 24% in the patients with mild stenosis and 15% in those with severe stenosis (p less than 0.01). This study reveals the importance of continuous wave Doppler echocardiography in assessing the atrial influence on left ventricular performance in patients with mitral stenosis.

Adult↗
PubMedDate not supplied

[The effect of cell phones on pacemaker function].

UNLABELLED: The aim of the study was to examine if there existed a risk from interference of cellular phones on patients with implanted permanent pacemakers. The study comprised 144 patients (134 VVI/VVIR and 10 DDD/DDDR) with permanent pacemakers of different manufactures. METHODS: During the routine pacemaker check, cellular phone aerial (Nokia 1610; GSM Standard) was placed against the skin of patients above the spot of pacemaker implantation, while the phone calls were repeated and ECG was continuously monitored. The effect of cellular phone on pacemaker was established upon: a) preexisting parameters of electric pacemaker stimulation; b) minimal ventricular rate of 90 beats/min, while electric stimulation parameters were set to their most sensitive values (MSV). RESULTS: Only in 9 (6.25%) patients was observed intermittent pacemaker inhibition, when pacemaker settings were on preexisting values of electric stimulation, while in 17 patients (11.8%) inhibition was noticed, when pacemaker settings were changed to their MSV. Besides, programmed values of electric stimulation in our patients remained unchanged. CONCLUSION: Although the electromagnetic interference interactions of cellular phones on pacemaker function were observed in relatively small number of our patients, we were of the opinion that pacemaker-dependent patients should avoid the use of cellular phones.

Adult↗
PubMedDate not supplied

[Transposition of the gracilis muscle in reconstruction of the anal sphincter].

UNLABELLED: Fecal incontinence is a serious psychological and social problem for the patient, frequently leading to social isolation, loss of working potential and depression. Different static and dynamic methods for the reconstruction of anal sphincter are used in the surgical treatment of the incontinence. At the Clinic for Plastic Surgery and Burns, at the Military Medical Academy, we have been using the method of transposition of the gracilis muscle, previously described by Pickerill-Broadbent (1952) since 1970. The aim of this paper was to describe our results in the treatment of fecal incontinence with the gracilis muscle. We have operated on 14 patients: 5 with congenital absence of the anus, 2 with myelomeningocele, 2 with the teratoma in the sacral region, 2 with the injury after the surgical procedure in the anal region and 3 with war injuries in the perineal area. After the detailed clinical and neurological examinations and pre-surgical preparations, we have performed the operation using the already mentioned technique (Pickerill). The following postoperative complications were identified: one hematoma and two minor dehiscences of the perianal wounds that healed per secundam. The electrostimulations of the transposed gracilis muscle were performed postoperatively. All the operated patients have been followed up for three years after the operation. In 9 patients the result was estimated as the excellent, in 3 as affordable and in 2 as the poor (occasionally, they could not contain the liquid fecal incontinence)? CONCLUSION: Due to its anatomical characteristics, the gracilis muscle is the most suitable for the reconstruction of the anal sphincter. If the correct indication is made, and if the surgery is well prepared and technically performed, with the maximal protection of neurovascular pedicle, an excellent postoperative result can be expected in over 60% cases.

Adolescent↗
PubMedDate not supplied

[Transient ischemic attacks and coronary disease].

Taking into consideration data from the literature that the most common cause of mortality of patients with transient ischemic attacks (TIA) is myocardial infarction, the aim of the study was to examine the state of coronary circulation in patients with TIA previously completely asymptomatic to coronary disease. There have been examined 40 patients with TIA previously asymptomatic to coronary disease and 14 patients with general characteristics similar to Parkinson's syndrome, also asymptomatic to coronary disease. All patients were subjected to neurological examination, echocardiography of carotid arteries, standard electrocardiography, X-ray of the heart and ergometry and, if indicated, coronarography. On the basis of the analysis of the results obtained it has been concluded that a significant number of patients with TIA, previously asymptomatic to coronary disease showed signs of coronary disease which imposes the necessity of correction of doctrinaire principles in prevention and follow up of these patients.

Coronary Disease↗