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Biomedical subjects

M Protich

Publications and source records attributed to M Protich.

At least 19 recordsLinked to original sources

[Immunoenzyme methods for determining thyroid hormones].

The analytical reliability of the immunoenzyme methods for determination of the thyroid hormones thyroxin, triiodothyronine, thyroid-binding globulin, thyrotropic hormone and the thyroid-binding capacity was examined by the peroxidase activity of the marker enzyme of "Specol-11" 28 healthy controls, 28 patients with subcompensated insulin-dependent diabetes with mean duration of 8.4 years and 11 patients with hypogonadism were examined. In the diabetic patients were found changes in their thyroid state characteristic for hypothyroidism--increased thyroxin and a decrease of the thyroid-stimulating hormone with a lowered level of the binding proteins. The patients with hypogonadism showed changes mainly in the binding proteins level, a decrease of the thyroid-binding capacity with 70%. The results reveal interrelations between the thyroid gland hormonal state and other hormonal disorders.

Adult

[Endothelial vascular desquamation in diabetics].

The endothelial vascular desquamation was studied in 32 diabetic patients and 150 healthy controls. In the diabetic patients a significantly high desquamation was found. No differences in the desquamation due to the type of diabetes, I or II, and its duration were found. The authors are of the opinion that the early vascular desquamation is the result of the high glycemia.

Chronic Disease

[A unique case of pseudohypoparathyroidism].

A case of pseudohypoparathyroidism is reported. The case presents with unusual features: primary hypogonadism (a rare feature) and several features undescribed until now with the syndrome--changes in the amino acid composition, coxae valgae, shallow fossa olecrani as well as normal values of the parathyroid hormones which is considered as a "phase state" due to the exhaustion of the secreting function of the parathyroid glands. The role of the G-unit in the etiology of the disease is discussed.

Adult

[New criterion for determining fertility in men].

The concentrations of testosterone, estradiol, LH and FSH were studied in blood plasma of 84 healthy males and in the seminal plasma of 22 fertile males. The results obtained are juxtaposed to the concentrations of the indicated hormones in seminal fluid of 35 males with oligoasthenospermia and of 46 males with azoospermia. The concentration of the hormones in the seminal plasma was established to be equal to their concentrations in blood plasma. That enables their investigation in the seminal fluid in parallel with the spermogram. Normal fertility is admitted to be that fertility with a concentration of testosterone ranging from 250-550 mg%, of estradiol from 40-60 pg/ml, of LH-25-35 mlU/ml and of FSH from 20-30 mlU/ml. Reduced fertility has the concentrations of testosterone and estradiol reduced with more than 50% of the normal level, and that of gonadotropic--elevated with more than 50% of the normal level.

Ejaculation