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Biomedical subjects

M Puchala

Publications and source records attributed to M Puchala.

14 recordsLinked to original sources
PubMed1993

[Recurrent exudative pericarditis--non-traditional therapy with colchicine].

Relapses are one of the most serious complications of exudative pericarditis. Optimal treatment which prevents exacerbation of the disease does not exist so far. Non-steroid antiphlogistic drugs are usually drugs of choice. Corticoids are used in more severe conditions or during frequent relapses. Development of a relapse, despite corticoid treatment, calls for more intense and prolonged corticoid treatment even when this treatment produces undesirable side-effects. Surgical methods do not always produce a lasting favourable effect, as the authors observed repeatedly in two patients from the group of patients referred to. The initial therapeutic findings after colchicine treatment in relapsing pericarditis are optimistic but it will be necessary to find in larger groups of patients the optimal method of implementation of this treatment.

Adult↗
PubMed1990

[Ebstein's anomaly of the tricuspid valve in adulthood].

Ebstein's anomaly is a rare congenital malformation of the heart, the basic feature of which is dislocation of the tricuspid valve into the right ventricular cavity. The frequently present dysplasia of the tricuspid valve is considered as integral part of this anomaly. Although affected subjects may reach adult age, it is no exception that the diagnosis of this anomaly in clinical practice is problematical, as apparent from the presented case-history. The authors emphasize the importance of two-dimensional echocardiography which provides very valuable morphological information needed not only for establishment of the diagnosis of this malformation but it makes it also possible to foresee the prognosis of the patient and the therapeutic tactics--conservative or surgical treatment.

Ebstein Anomaly↗
PubMed1990

[Chronic persistent cough and gastroesophageal reflux].

Respiratory complications of gastrooesophageal reflux are not rare. Their incidence is estimated to amount to as much as 20%. Chronic persisting cough as one of the respiratory complications of gastrooesophageal reflux is relatively rare (28%) but frequently is not assumed to be causally related to the reflux. The author attempted to elucidate this problem by description of individual cases and to find at the same time the most rational solution, as some procedures are, as regards availability of examination methods, costly and time consuming.

Adult↗
PubMed1990

[Neurologic and ophthalmologic complications of mitral valve prolapse].

The author investigated the incidence of cerebrovascular attacks in a group of 68 patients with mitral valve prolapse. In 10 of them (14.7%) he detected neurological and opthalmological symptoms. In six patients this symptomatology appeared for the first time, in four it had been recorded already in the past. Consistent with data in the literature, the author is in favour of the view that the neurological symptomatology in mitral with mitral valve prolapse is conditioned by a thromboembolic mechanism. The basis for the formation of micro- and marco- thrombi is an impaired continuity of the endothelium of the myxomatously degenerated cusps with subsequent deposition of thrombocyte aggregates and fibrin. In the conclusion the author discusses therapeutic procedures in the prevention of neurological relapses.

Adolescent↗
PubMed1989

[Gastroesophageal reflux and respiratory diseases].

Respiratory manifestations of gastrooesophageal reflux are not very well known and therefore frequently not recognized. The multifactorial character of these relations is confirmed by the fact that only 10% of the patients with gastrooesophageal reflux suffer from respiratory diseases. As these relationships are causal, successful treatment depends on their objectivization. Respiratory manifestations of gastrooesophageal reflux may be a serious and frequently the only symptom of reflux disease. When these causal relationships are not recognized, respiratory symptoms are not adequately treated and they develop gradually into chronic or frequently relapsing disease. It is therefore desirable that all patients with an obscure cause of chronic or relapsing respiratory disease are subjected to examination for gastrooesophageal reflux. Conservative or surgical anti-reflux treatment mitigates in the majority manifestations of respiratory complications or eliminates respiratory disease which has persisted for several years.

Adult↗
PubMed1989

[The importance of echocardiography in differentiating between cardiac amyloidosis and hypertrophic cardiomyopathy].

Due to the development of ultrasonic technique the possibilities of echocardiography extend, not only visualization of the anatomy of the heart, but also visualization of its function. In many instances information on the anatomy and function of the heart obtained by echocardiography is a sufficient basis for the assessment of the correct diagnosis. In rare instances the information is not sufficient. Conversely, conclusions made only on its basis is frequently the cause of undetected cardiac amyloidosis which is mistaken for hypertrophic cardiomyopathy. The author, based on his own observations and data in the literature, emphasizes the importance of structural changes of cardiac tissues which can be assessed objectively by echocardiography and are of decisive importance for the differentiation of the above diseases. The presence of granular sparkling in the interventricular septum and the other left ventricular walls, and frequently also in the right ventricular wall, in the atrial walls and thickening of the valves are very sensitive and specific echocardiographic signs of cardiac amyloidosis.

Aged↗