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Biomedical subjects

M Pugnani

Publications and source records attributed to M Pugnani.

15 recordsLinked to original sources
PubMedDate not supplied

[Radioactive isotopes in the diagnosis and therapy of tumors].

The Author, after some historical accounts, widely deals with physics and chemistry of the atom that are the necessary presupposition to the knowledge of the mechanisms of action of radio-isotopes. He hence exposes the radio-isotopes applications with special consideration to the action of radiations on the organism and the possibility of diagnosis and therapeutics with radioisotopes in oncology. The Author concludes that radio-isotopes must not be considered separately in the therapeutics of tumours, but as main component of the whole anti-tumour armament (surgical, consentional radiological, chemi-therapeutic) in which the immune-therapeutics is proving itself with fascinating possibilities.

Autoradiography↗
PubMedDate not supplied

[Metabolic changes following termino-lateral portacaval anastomosis in the rat].

The purpose of these present experiences was to evaluate some metabolic parameters, which can show liver damage after end-to-side porto-caval shunt, comparing the data with "sham operated" rats. At 180th day in each group the following parameters were controlled: ALT, AST, Alkaline phosphatase, gamma GT, bilirubin, Cholesterol, albumin and ammonia blood level. The results showed a significant increase of gamma GT, APh, bilirubin and ammonia blood level in porto-caval shunt operated rats.

Alkaline Phosphatase↗
PubMedDate not supplied

[Presence of dilatations of the aneurysm type in the abdominal aorta after experimental terminoterminal anastomosis in the rat].

We have examined the aneurysmal dilatations in the wall of abdominal aorta after microsurgical experimental operation of end-to-end anastomosis. We observed this alteration both by macroscopic examination and by optical light microscopy. The wall presents various damages, particularly in the media, that seems thick, disarranged and often necrotic.

Animals↗
PubMedDate not supplied

[A case of true diverticulum of the cecum].

Solitary diverticula of the large bowel are comparatively rare respect the much more frequent multiple diverticula. Such diverticula are found mainly in the caecum and ascending colon and are true diverticula, i.e. their wall is made up of all the layers of the bowel wall. When a solitary diverticulum of the caecum undergoes inflammation of the patients generally present with symptoms suggestive of acute appendicitis. A case of solitary diverticulum of the caecum in a 51 years old woman is described and discussed from the diagnostic and clinical as well as from the morphological and pathogenetic point of view.

Appendicitis↗
PubMedDate not supplied

[Use of an aldosterone antagonist in abdominal surgery].

Clinical and humoral signs of postoperative stress ore partly related to temporary hyperaldosteronism. The action of an aldosterone-antagonist was therefore studied on 24 abdominal surgical patients. The aldosterone-inhibitor has shown a consistent pharmacological and clinical effect. The drug seems then to be useful and safe-with close clinical and humoral follow-ups for the treatment of the postoperative secondary hyperaldosteronism.

Adult↗
PubMedDate not supplied

[Diagnostic and therapeutical uses of central venous catheterization (author's transl)].

The Authors have reviewed the diagnostic and therapeutical uses of central venous catheterization and its most common of introduction. Fifty-four consecutive cases of central venous catheterization via the subclavian route have been examined. The Authors have finally discussed the technique of introduction, the rate and nature of complications, the mean time of duration in place and the causes of catheter withdrawal.

Catheterization↗
PubMedDate not supplied

[Immunological problems in oncology (author's transl)].

The Authors, after a view of the problems of immunology, regarding the most recent discoveries, deal with the conclusions about the immunological reactions in research and clinical oncology. Many specific antibodies, formed as a result of the tumor, have been discovered in the field of research. It is impossible to say the same about human tumors and the probable hypothesis are numerous. The results until now obtained, even if they don't give a definite response, show that the immune defense of the organism has extreme importance for the beginning and the development of tumors, therefore further research could be a contribution to the cure of cancer.

Animals↗