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Biomedical subjects

M R Currin

Publications and source records attributed to M R Currin.

4 recordsLinked to original sources

Postoperative intensive care and the South African Society of Anaesthetists' patient category.

A group of 412 postoperative patients admitted to an intensive care unit of an academic hospital were evaluated in terms of their need for intensive care. The Acute Physiology and Chronic Health Evaluation score, the Therapeutic Intervention Scoring System (TISS) and the South African Society of Anaesthetists' (SASA) patient category were utilised to determine the level of care required by each patient. A further objective of the study was to determine if the SASA patient category, on its own, adequately described the need for intensive care in postoperative patients. Evaluation of the data indicated that, in terms of TISS, 66% of the patients required intensive care. These patients were distributed throughout all three SASA categories. Of the 137 patients who, according to TISS, did not require intensive care, 122 were SASA category 3 patients. However, of the total number of category 3 patients, just less than half required intensive care. In order to identify better those patients within a specific SASA category who require intensive care we suggest further subdivision of each category into groups A, B and C, according to the number of TISS points scored at 24 hours postoperation. In this way a retrospective audit using SASA categories would clearly identify those postoperative patients who required intensive care.

Anesthesiology

Pharmacology of the neonate.

Drugs need not necessarily be administered directly to the neonate, but may reach the newborn infant as a result of drug administration to the mother during gestation, at parturition, or during the course of lactation. The processes of absorption, distribution, metabolism and excretion of drugs in the neonate are discussed. Differences between the neonate and the adult in this regard are outlined. The pharmacology and pharmacokinetics of specific drugs to which the neonate may be exposed are discussed.

Acetaminophen