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Biomedical subjects

M R Eckstein

Publications and source records attributed to M R Eckstein.

9 recordsLinked to original sources
PubMed1988

Small bowel hemorrhage: angiographic localization and intervention.

Occult bleeding in the small bowel was localized with mesenteric angiography in 64 patients. Two groups of patients were identified. In the first group comprising 38 patients, bleeding sites were localized by the demonstration of contrast extravasation. In the second group of 26 patients, there was no extravasation. However, other angiographic findings suggested the source of bleeding. No active bleeding was necessary for a positive study in the second group. We conclude that in patients with suspected occult small bowel hemorrhage, mesenteric angiography helps localize the bleeding site. Clinically active bleeding is not always necessary, as angiographic findings other than extravasation may localize the source of hemorrhage.

Adult↗
PubMed1984

Gastrointestinal bleeding. An angiographic perspective.

Angiography has become an integral tool in the management of patients with gastrointestinal bleeding. It is used for localizing the site of bleeding and then for controlling the bleeding when more conservative methods of treatment are unsuccessful.

Angiography↗
PubMed1984

Aortofemoral bypass grafts: safety of percutaneous puncture.

To assess the safety of percutaneous puncture for the angiographic study of aortofemoral bypass grafts, we reviewed the medical records of 58 patients who underwent a total of 86 graft punctures. Short- and long-term follow-up revealed that in 83 punctures there were no complications. In three instances (3.5%) there was acute thrombosis of the punctured limb of the graft. This complication may have expedited but did not substantially alter the surgical plans of managing the underlying clinical problem. Although the incidence of complications of direct graft puncture is higher than that associated with puncture of native vessels, alternative approaches are also associated with complications, many of which may be more serious. Therefore, for angiographic studies of patients with aortofemoral bypass grafts, we favor the direct percutaneous puncture provided that enough time has elapsed from surgery.

Adult↗
PubMed1984

Gastric bleeding: therapy with intraarterial vasopressin and transcatheter embolization.

Angiographic therapy to control gastric bleeding was attempted in 200 patients. One hundred ninety-four patients were treated with intraarterial vasopressin and 17 of them were also treated with transcatheter embolization. Six patients underwent primary embolization, and an additional six received intravenous vasopressin. The initial rate of bleeding control in all patients angiographically treated was 73%. When embolization was used in some of the patients who did not respond to vasopressin, the overall control rate increased to 79%. Recurrent bleeding occurred in 18%. When angiographic therapy was attempted again in the patients with recurrent hemorrhage, the bleeding was stopped in 36%. Major complications occurred in 6.5% and minor in 17.5%. Of the patients with bleeding that was angiographically controlled, 73% survived and 27% died of associated clinical conditions. Among the failures of angiographic therapy, 48% died during the same hospital admission. Intraarterial infusions of vasopressin or transcatheter embolization are useful for the control of gastric bleeding.

Adolescent↗
PubMed1984

Interventional angiography of the renal fossa.

In this article, the authors present an overview of interventional procedures that aim at (1) opening of the renal artery with percutaneous transluminal renal angioplasty, intra-arterial thrombolysis, and/or transcatheter thromboembolectomy and (2) reducing or obstructing renal artery blood flow with transcatheter embolization.

Adenocarcinoma↗
PubMed1971

Amino acid oxidase of leukocytes in relation to H 2 O 2 -mediated bacterial killing.

D-Amino acid oxidase and L-amino acid oxidase have been measured in sucrose homogenates of polymorphonuclear leukocytes (PMN) obtained from guinea pigs and humans. Subcellular distribution patterns and studies on latency indicate that these oxidases are soluble enzymes. Their hydrogen peroxide-generating capacity was verified. Chronic granulomatous disease PMN, which lack a respiratory burst and fail to generate H(2)O(2) during phagocytosis and do not kill catalase positive bacteria, had peroxide-generating amino acid oxidase activity equal to that found in PMN homogenates from patients with bacterial infections. The precise metabolic and bactericidal role of amino acid oxidases in PMN remains uncertain.

Amino Acid Oxidoreductases↗
PubMedDate not supplied

The normal leg venogram: significance in suspected vein thrombosis.

Does a normal leg phlebogram exclude deep venous thrombosis (DVT)? Is it safe not to anticoagulate patients with suspected DVT and a normal phlebogram? To answer these questions a retrospective study was undertaken of 71 outpatients with clinically suspected DVT and a normal phlebogram. Patients were followed for 5 months on the average; data were obtained from conversations with referring physicians and interviews with patients. Nine patients were excluded from the study because of incomplete follow-up data; four others were excluded because they were treated with coumadin "on clinical grounds". Five patients continued having symptoms subsequently attributed to arthritis, cellulitis and/or venous stasis. Fifty-three patients had no venous thromboembolic problems during the follow-up period and their symptoms subsided without therapy. We conclude that a properly performed normal leg phlebogram excludes a diagnosis of clinically significant DVT. No patient in this study developed problems because anticoagulant therapy was withheld based on a negative phlebogram.

Anticoagulants↗