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M R Kaiser

Publications and source records attributed to M R Kaiser.

3 recordsLinked to original sources
PubMed2000

Is there a special relationship between CD30-positive lymphoproliferative disorders and epidermal proliferation?

The relationship between CD30+ lymphoma and epithelial proliferations is not well defined. CD30+ lymphoma and lymphomatoid papulos (LyP) share immunohistochemical epitopes and some other features. A single case of LyP associated with multiple keratoacanthomas (KAs) was recently reported. We report two cases of atypical lymphocytic proliferation with features of CD30+ lymphoma and LyP intimately associated to KA and squamous cell carcinoma (SCC), KA type. This similar combination of an epidermal tumor and apparent involvement with atypical lymphocytic infiltrates raises the possibility of an association between the two entities. We speculate that the association may be more than expected to occur by chance and suggest several mechanisms by which the association may evolve.

Aged↗
PubMedDate not supplied

Effect of ultraviolet radiation-induced inflammation on epidermal wound healing.

To examine the influence of ultraviolet radiation, a potent inducer of interleukin-1 and other growth factors, on the rate of epidermal migration, we used a porcine model of wound healing. Wounds were treated in one of the following treatment groups: (1) two minimal erythema doses of ultraviolet radiation once daily for 2 days before wounding, (2) two minimal erythema doses of ultraviolet radiation once daily for 2 days before wounding followed with continuous treatment until all wounds were 100% epithelized, (3) or no ultraviolet radiation treatment until healing was complete. Using a macroscopic salt-split technique, we examined epidermal specimens macroscopically for epithelialization. Treatment both before and after ultraviolet radiation significantly enhanced epithelialization when compared with non-ultraviolet radiation-treated control wounds. These experiments show that ultraviolet radiation treatment can augment the rate of healing of partial-thickness wounds.

Journal Article↗