Effects of oral stimulation on the cephalic phase of pancreatic exocrine in dogs.
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Biomedical subjects
Publications and source records attributed to M R Kare.
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The acceptability of heated soybean meal (HS) compared to raw soybean flakes (RS) was studied by means of diet selection in free choice situations. The selection by rats of diets containing HS over those containing RS was shown in short- and long-term preference tests. Texture did not seem to be an important factor in the acceptability difference between HS and RS. Rats selected a less nutritious diet containing RS + sodium saccharin (appealing taste) over a diet containing HS + sucrose octaacetate (aversive taste) for an initial 6 to 7 days, suggesting that post-ingestional factors did not markedly affect the acceptability during that period. However, after this initial period, the rats selected the diet of higher nutritive value, even though it had added sucrose octaacetate. Preference tests before and after producing anosmia indicated that RS contains an aversive odor(s) which could be removed by vacuum treatment. Heated soybean meal was found to contain an appealing taste stimulus (i) which could also be removed by vacuum treatment.
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Whole-body autoradiographic stuidies demonstrated that, when isotopically labeled glucose is placed in the ligated oropharynx, there is a rapid movement of the isotope directly to the intracranial cavity. This passage involves nonspecific diflision, bypassing all recognized rouctes to the brain.
1. Lipase, protease and amylase activity in canine pancreatic juice were determined during the feeding of basal, high fat, high protein and high carbohydrate diets for 3-week periods.2. The level of lipase in pancreatic juice was significantly augmented by increasing the dietary intakes of fat (P < 0.05) and carbohydrate (P < 0.05) but was not affected by increasing the protein intake.3. Protease activity was highly augmented by increasing the intake of protein (P < 0.01), was less strongly augmented by increasing carbohydrate (P < 0.10), but was not affected by the level of dietary fat ingested.4. Enzyme activities in canine pancreatic juice were modified by the nature of the diet on which the animals were maintained and the response for a given enzyme may be influenced by more than one dietary constituent.
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