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Biomedical subjects

M R McDaniel

Publications and source records attributed to M R McDaniel.

9 recordsLinked to original sources

Rate of maillard browning in sweet whey powder.

The objective of this study was to evaluate the rate of Maillard browning in 3 commercial sweet whey powders (WC1, WC2, and MW1), under accelerated shelf-life testing (ASLT) and under normal storage conditions (21 degrees C and 35% RH). Rate of brown pigment formation (k) obtained from short-term ASLT of whey powder was compared with actual findings obtained from the long-term shelf-life testing under normal conditions. Deterioration by Maillard browning, measured by spectrophotometer, was compared with changes in color (Hunter Laboratory), free moisture, titratable acidity, and sensory attributes. Results suggest that estimated k (from ASLT) was comparable with the observed rate (obtained at ambient temperature) for 2 producers (WC1, MW1). The actual k values observed for samples WC1, WC2, and MW1, stored under normal conditions, were 0.0031, 0.0080, and 0.0148 color units/g of solid per mo, respectively. The estimated values of k for samples WC1, WC2, and MW1 were 1.12, 4.90, and 1.35 times more than the observed values, respectively. The Q10 values (increase in reaction rate for a 10 degrees C temperature increase) ranged from 1.77 to 4.14, and the activation energies ranged from 15.9 to 28.4 kcal/mol. Hunter Laboratory values L* and a* appeared most sensitive to changes during storage. Free moisture content, and acidity increased significantly with storage. However, no significant changes were detected by the sensory panel in the attributes considered.

Chemical Phenomena↗

Preference mapping of Cheddar cheese with varying maturity levels.

The objective of this study was to evaluate the flavor profile and acceptability of 7 Cheddar cheeses of varying maturity using descriptive analysis and consumer acceptance tests. Cheddar cheeses (n = 7) ranging in age from 1 to 19 mo were selected based on age, geographic region, and flavor profile. Descriptive sensory profiles of selected cheeses were determined using a trained panel (n = 14) and an established cheese flavor sensory language. Cheeses were evaluated for consumer acceptability in two demographic locations: North Carolina and Oregon. Consumers (n = 100 at each location) assessed the cheeses for overall liking and other consumer attributes. Cheddar cheeses demonstrated distinct differences in descriptive sensory profiles. Average consumer responses between the two locations were not different. Six distinct consumer clusters were identified, and the number of consumers in these clusters differed between the two locations. Consumers differentiated "young" and "aged" cheese flavor, but both young and mature cheeses were perceived by consumers as exhibiting intense Cheddar cheese flavors. Cheddar cheese acceptance varies widely among consumers and is related to consumer preferences for distinct cheese flavor profiles.

Cheese↗

Using pharmacists' documentation of clinical activities to reclaim employees and reposition the department.

The use of documentation on pharmacist clinical activities to encourage greater hospital investment in a department is described. From 1983 through 1988, the number of full-time-equivalent (FTE) positions in the pharmacy department at a 468-bed medical center was reduced from 63 to 39.4. To cope with the challenge of a sharply reduced staff, the department established a permanent pharmacy-nursing task force, developed a pharmacy strategic plan, used total quality management, recruited the best staff possible when openings appeared, and held staff retreats. In addition, measures were taken to begin documenting all pharmacist clinical activities online. As data were accumulated, it became clear that more pharmacist involvement in patient care areas was needed and that more resources would be necessary to achieve that. Presentations were made to hospital administration to demonstrate the existing and potential contributions of the department; the presentations drew heavily on the clinical documentation. Formal reports were also submitted. As a result, the department received approval for a pharmacist career ladder, an increase of 1.6 pharmacist FTEs for the evening shift, a large salary-range adjustment for staff pharmacists, and an increase of 1 pharmacist FTE to focus on antimicrobial use. A pharmacy department successfully used documentation of its clinical activities to make a case to administration for reclaiming some of the pharmacist FTEs lost through downsizing.

Computer Systems↗

Toward a safer label.

Pharmacy literature has reminded hospital pharmacists that our computer generated intravenous and medication labels often fall short in the area of legibility and usability. A new computer system and Zebra Stripe S-500 printers (Zebra Technologies Corporation, Vernon Hills, IL) allowed Methodist Medical Center to reexamine our labels and to join with nursing to develop a safer, more user friendly set of labels. These new labels have been well received by our nursing staff.

Clinical Pharmacy Information Systems↗

Development of a methylprednisolone protocol for use in acute spinal cord injuries.

Acute spinal cord injury is a serious medical condition that results in 10,000 new cases of paralysis each year. Initial physical damage to the spinal cord is followed by chemical damage, resulting in cell death and scar tissue formation. Methylprednisolone therapy has proven effective in suppressing the chemical damage, particularly when started within 8 hours of injury. A protocol developed by the Pharmacy Department at Methodist Medical Center in Dallas, Texas, is described. This protocol facilitates accurate, efficient preparation and administration of this emergency therapy. The protocol takes advantage of the pharmacist's unique expertise to lessen the risk of calculation errors and mistakes in preparation, by providing a tailored drug admixture for administration at a fixed flow rate. The protocol and a sample of the pharmacy work sheet are presented.

Clinical Protocols↗

Sensory characterization of human milk.

Fore and hind milks from a single morning feed collected from 24 nursing mothers over 3 consecutive d were evaluated for sweetness, viscosity, and mouthcoat by a trained adult panel using magnitude estimation. Milks were perceived as sweet, thin, and low in mouthcoat. Hind milks were slightly more viscous and mouthcoating than fore milks. The higher fat content in hind milk was associated with higher estimation of physical viscosity. Milk fat content decreased as maternal age increased. Significant differences occurred between milks in lactose, fat, and protein contents. By use of a sweetness power function curve, the sweetness intensity of human milk was estimated as equivalent to a 2.12% sucrose solution.

Adult↗