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Biomedical subjects

M R McGuire

Publications and source records attributed to M R McGuire.

4 recordsLinked to original sources

Sprayable self-encapsulating starch formulations for Bacillus thuringiensis.

Under glasshouse conditions, various cornstarches and adjuvants were examined as encapsulating agents in sprayable formulations for Bacillus thuringiensis subsp. kurstaki Berliner. When these materials were suspended in water and tested for physical factors such as viscosity, clumping, and retention on plant surfaces, a range of responses was observed. All formulations tested had acceptable viscosity, but some formulations clumped. When applied to cotton leaves, certain formulations remained less than 4 d, whereas others remained greater than 2 wk. One of these formulations containing equal parts of Mira-sperse (a commercially available pregelatinized cornstarch) and sucrose (6% total solids) was selected for testing persistence of B. thuringiensis insecticidal activity against Ostrinia nubilalis Hübner neonate larvae. When encapsulating agents were present, insecticidal activity decreased over a 2-wk period significantly more slowly than when encapsulating agents were absent. This indicates an enhanced persistence of B. thuringiensis under glasshouse conditions. Implications of a sprayable self-encapsulating formulation for B. thuringiensis are discussed.

Aerosols

Comparative analysis of ankle arthroplasty versus ankle arthrodesis.

In a retrospective study of 41 patients with total ankle arthroplasty (25 patients) and ankle arthrodesis (18 patients), the mean follow-up period was 3.8 years for total ankle arthroplasties and 3.3 for ankle arthrodeses. Sixteen of the 23 ankle arthroplasty patients, and 17 of the 18 arthrodesis patients had good or excellent results. Total ankle arthroplasty was successful in patients with rheumatoid arthritis, but not posttraumatic arthrosis. Total ankle arthroplasty is indicated in rheumatoid patients with severe ankle involvement who have not responded to medical management. It also may be used in the elderly or debilitated patients who will place minimal stress on the ankle. The elderly may not tolerate the prolonged immobilization or repeated operations that fusion may require. Total ankle arthroplasty should not be used in young patients with posttraumatic arthrosis.

Adult