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Biomedical subjects

M R Paling

Publications and source records attributed to M R Paling.

At least 37 records · Page 2Linked to original sources
PubMed1983

Adrenal involvement in non-Hodgkin lymphoma.

Adrenal masses are described in seven cases of non-Hodgkin lymphoma in a series of 173 patients. In all seven patients the lymphoma was diffuse rather than nodular. Three patients had adrenal masses at the time of presentation, whereas in four cases the adrenal gland was a site of tumor recurrence after therapy. Three patients had simultaneous bilateral adrenal involvement by tumor. No characteristic features were recognized that might have distinguished these tumors from other adrenal masses. Appropriate therapy successfully resolved the adrenal masses in all but one case. The latter patient was the only one with evidence of adrenal insufficiency.

Adrenal Gland Neoplasms↗
PubMed1982

Scoliosis in cystic fibrosis--an appraisal.

An unusually high prevalence (10%) of scoliosis is described in a series of 151 patients aged four years and older with cystic fibrosis. The scolioses were of the late onset (juvenile and adolescent) type, being typically thoracic with the curve convex to the right, although there was no significant preference for either sex. No direct relationship was found between the spinal curvature and the severity or distribution of the lung disease, although the worse scolioses tended to occur in patients with relatively severe pulmonary involvement. There was no evidence of metabolic bone disease as a predisposing cause. Some indication of a familial tendency towards scoliosis was apparent, and a genetic or constitutional basis is postulated with an unknown precipitating factor.

Adolescent↗
PubMed1982

Computed tomography in malignant fibrous histiocytoma.

The computed tomographic findings in 11 cases of malignant fibrous histiocytoma are discussed. The typical appearance of the eight primary tumors imaged was of a poorly marginated mass with an attenuation coefficient slightly lower than that of normal muscle. Central tumor necrosis was detected in three cases. Three of five abdominal tumors showed involvement of adjacent soft tissue structures, and one demonstrated destruction of adjacent bone. The nonspecific appearance of these tumors prevented their reliable differentiation from other soft tissue sarcomata.

Abdominal Neoplasms↗
PubMed1982

Paranasal sinus obliteration in Wegener granulomatosis.

The authors report 14 cases of Wegener granulomatosis in which one or more paranasal sinuses were obliterated by bone. The maxillary antra were involved in all cases, with the other sinuses being affected less frequently. These changes are thought to result from chronic bacterial sinusitis superimposed on the granulomatous vasculitic process. Computed tomography dramatically demonstrated the bone changes, consisting of a combination of sinus wall thickening and trabeculated new bone formation within the sinuses.

Adolescent↗
PubMed1982

The sonographic appearance of metastatic malignant melanoma.

The sonographic findings in the abdomen in 42 patients with intra-abdominal metastases from malignant melanoma are described. Multiple metastatic sites were seen in 10 of the 42, with the liver being the organ most often involved. Liver metastases were predominantly of low echo amplitude, and fluid was visible within 30 per cent of all metastases, probably being an indicator of the frequency of hemorrhage into these lesions. Bulky disease, especially in the retroperitoneum, was unusual in the patients examined, which probably accounts for the absence of hydronephrosis as a complication.

Abdominal Neoplasms↗
PubMed1981

Abdominal ultrasound in advanced ovarian carcinoma.

The ultrasonic appearance of pelvic tumor and intra-abdominal dissemination is reported in 57 patients with advanced ovarian carcinoma. The primary pelvic tumor was found to be solid or mixed solid-cystic. In no case was the primary malignancy exclusively cystic. In 23 patients, intra-abdominal extrapelvic tumor was detectable, and in eight patients there were solid liver metastases. The usefulness of both static and real-time ultrasound scanning is detecting stage III and IV disease is discussed.

Abdomen↗
PubMed1980

Radiation osteitis: a problem of recognition.

Localized changes of radiation necrosis in 6 patients treated for Ewing sarcoma are described. Well-circumscribed lytic areas in the cortex of a previously irradiated long bone may be mistaken for tumor recurrence, especially if they are few in number and surrounded by relatively normal bone. The clarity of demarcation of these lesions, their progression, and the lack of a periosteal reaction are stressed.

Adolescent↗
PubMed1979

Contrast dose for enhancement of computed tomograms of the brain.

This study shows that contrast enhancement of cerebral lesions can be adequately achieved with a bolus injection of 60 ml of sodium iothalamate 70%. While the infusion of a larger dose of contrast agent increases quantitatively the level of enhancement of a variety of lesions, this method of examination does not appear to provide any more useful diagnostic information, and it introduces added and unnecessary inconvenience, cost and potential hazard.

Brain↗
PubMedDate not supplied

Ultrasonic evaluation of therapeutic response in tumors: its values and implications.

Not only may ultrasound demonstrate the presence of a tumor mass at various sites in the abdomen, but it may also be useful in measuring the size of the mass. The rate of tumor growth or regression was followed by ultrasound in 28 patients with ovarian carcinoma undergoing chemotherapy. The ability of ultrasound to make precise measurements of tumor size is discussed, and the value of these measurements is explored. This quantification may be valuable in the assessment of therapeutic response in pelvic cancer, and the technique may be applicable to other intra-abdominal mass lesions.

Adenocarcinoma↗
PubMedDate not supplied

Lower lobe collapse due to pleural effusion: a CT analysis.

In the presence of a pleural effusion, volume loss is seen in the adjacent lung, primarily in the lower lobe. With a modest effusion a compliant lower lobe may show displacement and generalized volume loss without focal atelectasis, but more commonly segmental atelectasis does occur, typically in the posterior basal segment. Large effusions result in a major degree of lower lobe collapse. The collapsed lobe tends to be uplifted by the fluid and compressed toward the hilum with consequent stretching and attenuation of the inferior pulmonary ligament, rather than collapsing posteriorly and medially.

Adult↗
PubMedDate not supplied

Respiration artifacts in MR imaging: reduction by breath holding.

Respiratory motion commonly produces degradation of image quality on magnetic resonance scans of the upper abdomen due to artifacts produced in the direction of the phase encoding gradient. Such artifacts may be reduced, although not eliminated, on image sequences obtained with relatively short acquisition times by means of breath holding during the middle 20% of the sequence.

Diaphragm↗
PubMedDate not supplied

Tumor invasion of the anterior skull base: a comparison of MR and CT studies.

Seven patients who had tumors arising in the anterior face or paranasal sinuses and invasion of the anterior skull base were evaluated with magnetic resonance (MR) and high resolution CT. Magnetic resonance was superior in evaluating tumor encasement of the carotid artery and invasion of the cavernous sinus; for assessing the relationship of the tumor to the anterior brain, optic nerves, and optic chiasm; in providing coronal images free from dental artifact; and in determining tumor extent within the infratemporal fossa. Bone destruction was more easily observed on CT than MR.

Adult↗