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M R Sapin

Publications and source records attributed to M R Sapin.

119 records · Page 7Linked to original sources
PubMedDate not supplied

[Scope of lymphadenectomy in organ-sparing operations in kidney cancer patients].

Organ-saving operations (extended lymphadenectomy) were performed in 125 patients with renal carcinoma (RC) in the urological clinic of I. M. Sechenov Moscow Medical Academy between 1992 and 2002. In view of specific segment-by-segment lymph flow off the right and left kidneys, it is thought valid to remove paracaval and aortocaval lymph nodes in saving operations on the right kidney but in cancer of the left kidney it is recommended to remove paraaortic lymph nodes. Basing on the anatomical features, lympho-dissection should be made from the crus of the diaphragm to bifurcation of the aorta. Metastases to the regional lymph nodes were diagnosed in 12 (9.6%) patients. In 8 of 12 patients with pN+ lymph node metastases were microscopic. Frequency of lymphogenic metastases directly correlated with the size and stage of the tumor, cancer cells differentiation degree. Metastatic involvement of the regional lymph nodes in renal cancer is an unfavourable prognostic factor as 5-year survival for the overall group of patients was 71.7% while for patients with pN+ it was 41.7%.

Humans↗
PubMedDate not supplied

[The cell composition and cytoarchitectonic characteristics of the lymphoid formations in the kidney pelvis and ureter of adults].

Quantitative characteristics, cell composition and cytoarchitectonics are characterized for lymph nodules in the walls of renal pelvis and ureter according to the findings in 14 total autopsied specimens of the pelvis and ureter obtained from 7 females and males aged 22-60. All of them had been killed in accidents and were free of urogenital, hematological, immune and lymphatic diseases. As indicated by histological sections, lymph nodules in the pelvic and ureteral mucosa of the examinees did not contain clear reproduction centers. The cells of the above lymph nodules comprised primarily small and medium-sized lymphocytes as well as reticular cells. Blast cells and macrophages were not numerous and averaged 2.6% of the total cell population. The count of cells undergoing destruction remained stable and made up from 1.57 +/- 1.6 to 3.52 +/- 2.06%. As for cytoarchitectonics, typical for the nodules was the existence of pairs, groups and chains of small and medium-sized lymphocytes.

Adult↗