PubMed HealthSearch

Biomedical subjects

M R Seitz

Publications and source records attributed to M R Seitz.

10 recordsLinked to original sources

Response asymmetry and binaural interaction in the auditory brain stem evoked response.

Asymmetry in the auditory brain stem evoked response (ABR) and its effect on measurements of binaural interaction were studied. Monaural and binaural ABRs were recorded from 24 normal hearing subjects at two sensation levels: 70 and 50 dB. Monaural responses were judged to be asymmetrical when the right response minus the left response resulted in a difference trace which was significantly greater than the level of the background noise in the ABR. It was found that sensation level significantly affected the frequency of monaural response asymmetry and that the amplitude of the derived binaural interaction component (BIC) was positively correlated with the degree of asymmetry present. Offsetting the asymmetry by introducing an interaural intensity difference resulted in a significant reduction in the amplitude of the BIC. It was concluded that the BIC is affected by factors other than those which can be attributed solely to binaural interaction.

Acoustic Stimulation

Auditory processing in spinal cord injury: a preliminary investigation from a sensory deprivation perspective.

Research on sensory deprivation suggests that the loss of somatosensory input to the central nervous system may have an impact on cortical reactivity and subsequent cognitive task efficiency. Individuals with spinal cord injury have a permanent loss of such input to varying degrees. However, there have been few investigations of cognitive processing in spinal cord injury. In this study, six outpatients with quadriplegia and 12 able-bodied controls were administered a dichotic listening task while auditory evoked response data and auditory threshold data were recorded. There were no differences between groups in terms of auditory threshold or auditory evoked responses. However, the outpatient quadriplegic group was more successful than the able-bodied controls in performing the dichotic listening task at one but not all levels of complexity. Results suggest that differences in cognitive processing ability between spinal cord injured and able-bodied individuals may reflect higher level motivational attention-concentration differences rather than more basic auditory and neurophysiologic processing differences.

Analysis of Variance

Iris color and hearing loss.

This study investigated the relation between iris color and hearing loss in 261 adult textile workers exposed to either a low-noise environment (below 85 dB) or a high-noise environment (above 102 dB). The subjects included 48% white males, 28% white females, 15% black males, and 9% black females. No relation was found between iris color and hearing loss in the control or low-noise group. A significant relation between iris color and hearing loss or hearing threshold levels was found for workers in the high-noise environment. Other variables, however, were found to predict susceptibility to hearing loss better than iris color alone.

Adolescent

Modeling HTL of industrial workers using multiple regression and path analytic techniques.

This study compared path analytic with multiple regression analyses of hearing threshold levels (HTLs) on 258 adult textile workers evenly divided into low- and high-noise exposure groups. Demographic variables common in HTL studies were examined, with the addition of iris color, as well as selected two-way interactions. Variables of interest were similarly distributed in both groups. The results indicated that (1) different statistical procedures can lead to different conclusions even with the same HTL data for the same Ss; (2) conflicting conclusions may be artifacts of the analytic methodologies employed for data analysis; (3) a well-formulated theory under which path analytic techniques are employed may clarify somewhat the way a variable affects HTL values through its correlational connections with other antecedent variables included in the theoretical model; (4) multicollinearity among independent variables on which HTL is regressed usually presents a problem in unraveling exactly how each variable influences noise-induced hearing loss; and (5) because of the contradictory nature of its direct and indirect effects on HTL, iris color provides little, if any, explanatory assistance for modeling HTL.

Adult

Central tinnitus--diagnosis and treatment. Observations simultaneous binaural auditory brain responses with monaural stimulation in the tinnitus patient.

Central tinnitus is defined as an abnormal sensation of sound which is perceived by the patient and established by neurotologic diagnosis to be retrocochlear and/or within the central nervous system in location. A method of diagnosis and evaluation using evoked response audiometry (ABR) is reported. A clinical test, Simultaneous Binaural Auditory Brain responses with monaural stimulation (ABR) for central location of tinnitus is presented. The use of a diagnostic approach to the selection of a tinnitus masker will be presented. Electrophysiologic indices for central tinnitus have been observed based on short latency ABR recordings. A classification has been presented. The use of lidocaine I.V. therapy with ABR recordings is presented. The concept, diagnosis, and techniques at this time, relating to central tinnitus, are presented as clinical observations. These observations are a beginning for the establishment of an electrophysiologic series of indices which can be interpreted as an electrophysiologic correlate of tinnitus to be supported by basic clinical research.

Audiometry

Identifying deafness in the newborn.

The necessity of early identification of hearing loss has long been urged by otolaryngologists, pediatricians, audiologists, and others working with the deaf. Yet there have been difficulties in implementing accurate and cost-effective newborn hearing screening programs. This article reviews some of the history of infant screening programs, discusses various areas of research related to stimulus and response parameters, and outlines a screening program, designed to fit new recommended procedures, currently under way in Halifax.

Acoustic Stimulation

Brainstem electrical responses from selected tone pip stimuli.

Brainstem-electrical responses were obtained from 10 normal hearing adult subjects using frequency specific tone pips as stimuli. The four frequency specific tone pips (500, 1000, 2000, and 4000 Hz) were diamond shaped with a 2.5-msec rise/fall time. Each tone pip was presented at four intensity levels (70, 50, 30, and 10 dB hearing threshold level), and graphic recordings were made for each frequency at the specific intensity levels. Frequency specific Wave V intensity-latency functions were plotted, and these results were compared to tone pip data obtained in previous studies. In addition, suggested test procedures for obtaining tone pip brainstem-evoked responses under diagnostic conditions are discussed.

Acoustic Stimulation