Ophthalmologic manifestations of GU disease.
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Biomedical subjects
Publications and source records attributed to M R Shetty.
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Umbilical metastases from known and unknown primary cancers are rare. The eponym "Sister Mary Joseph's nodule" has been used by generations of physicians. The first reports of this clinical sign were from Walshe in 1846. A review of the literature revealed 265 cases from then until 1989. Only 85 cases of umbilical metastasis from unknown primary tumors were found. This review should help us to focus on the common and uncommon primary sites in the diagnosis of patients with this finding. A single case report and the work-up for the hidden primary tumor are described.
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In the year 1795, a British East Indiaman bound for China had a sick sailor on board who was diagnosed as having testis cancer by the ship's surgeon, who then treated him with an antiscorbutic diet, because scurvy was rampant among the sailors. He was completely cured of his cancer, as reported in the Edinburgh Medical and Surgical Journal by Livingstone in 1805. However, the sailor actually had scurvy and not testis cancer. This diagnostic error has been perpetuated in the medical literature until rectified by Shetty after 191 years. This is reconstructed account of the sailor's case history and the ship's journey as it actually took place in 1795 AD.
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