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Biomedical subjects

M R Walcoff

Publications and source records attributed to M R Walcoff.

2 recordsLinked to original sources

Evoked potentials in multiple sclerosis.

Short-latency somatosensory short-latency auditory, and pattern evoked visual potentials were recorded in 115 patients with suspected, possible, probable, or clinically definite multiple sclerosis. An abnormality of at least one evoked potential was found in 94% of the clinically definite cases, in 67% of the summed suspected, possible, and probable cases, and in 80% of the entire series. Abnormalities of all three modalities of evoked potentials were correlated with severity of illness. Short-latency auditory evoked potential abnormalities were correlated with clinical judgement in respect to localization of lesions and activity of disease.

Adult↗

Comparison of phenytoin and phenobarbital effects on far-field auditory and somatosensory evoked potential interpeak latencies.

Far-field somatosensory and auditory evoked potential (EP) interpeak latencies were measured in normal controls, epileptics not receiving medications, and epileptics receiving phenytoin, phenobarbital, or both. Phenytoin, but no phenobarbital, was associated with a prolongation of EP interpeak latencies at serum level concentrations over 20 micrograms/ml. Neither carbamazepine nor primidone in smaller series were associated with prolongation of EP interpeak latencies.

Epilepsy↗