AGE CHANGES IN SIZE AND NUMBER OF THE GIANT MITOCHONDRIA IN THE FLIGHT MUSCLE OF THE COMMON HOUSEFLY (MUSCA DOMESTICA L.).
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Biomedical subjects
Publications and source records attributed to M ROCKSTEIN.
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Magnesium-activated adenosine triphosphatase activity in the giant mitochondria (sarcosomes) of the flight muscle of aging male houseflies decreases concomitantly with failure in flight as reflected in the loss of wings during the second week of adult life. Preceding the loss of wings, however, there is a rapid decline in the activity of an alpha-glycerophosphate dehydrogenase which is located in the extramitochondrial fraction and is dependent on nicotinamide adenine dinucleotide.
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Under standard conditions of temperature, humidity, and (artificial) diet, loss in flight ability is paralleled by a decline of up to 66(2/3) percent in activity of enzymes dephosphorylating organophosphorous compounds in the thoracic flight muscle. Concomitantly, the content of adenosine triphosphate in the flight muscle increases five times, while the content of adenosine monophosphate correspondingly diminishes.
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