Passive smoking and coronary heart disease.
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Coronary Disease↗
Biomedical subjects
M Rabinoff
Publications and source records attributed to M Rabinoff.
Short note: iron, infection and acute myocardial infarction.
Recent studies have noted an association between both increased serum ferritin and dietary iron intake and acute myocardial infarction (AMI). The possible role of increased serum ferritin and dietary iron intake in the promotion of infection, and in the etiology of AMI, is discussed. In addition, the possible role of infection in the etiology of coronary heart disease and AMI is also discussed.
Diet↗
Short note: possible role of macrophage metabolic products including quinolinic acid and neopterin in the pathogenesis of inflammatory brain diseases.
It is hypothesized that macrophage metabolic products, including the possible neurotoxic NMDA receptor agonist quinolinic acid, and neopterin, may play a role in the pathogenesis of inflammatory brain diseases. It is suggested that the production of neopterin may have physiological roles, including to inhibit folate synthesis in intracellular pathogenic microorganisms and to inhibit viral nucleic acid synthesis. The possible role of excess neopterin production during chronic infection in the pathogenesis of inflammatory brain diseases is discussed.
Biopterins↗
Mononuclear metabolic products and human immunodeficiency virus-associated neurological damage.
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Central Nervous System Diseases↗
Caution required in developing HIV vaccine.
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Female↗
Interferon-gamma, neopterin and host defense.
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Biopterins↗
Possible uses of urinary neopterin and biopterin measurement.
The measurement of urinary neopterin and biopterin may be an important non-specific diagnostic tool. Urinary biopterin has been found to be decreased in parkinsonian patients, and in hyperphenylalanemia as a variant of phenylketonuria. Urinary neopterin has been found to be elevated in numerous conditions. It has been shown to be significantly higher in AIDS patients than in ARC patients, and significantly higher in ARC patients than in controls. Urinary neopterin has been shown to be prognostically elevated in a wide range of neoplasias, including multiple myeloma, hematologic and gynecologic neoplasias. Neopterin is thought to be an in-vitro indicator of activation of the immune system.
AIDS-Related Complex↗