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Biomedical subjects

M Rademaker

Publications and source records attributed to M Rademaker.

At least 37 records · Page 2Linked to original sources

Diagnostic accuracy of teledermatology: results of a preliminary study in New Zealand.

AIM: To determine the accuracy of a video conferencing system (telemedicine) in diagnosis of dermatological disorders. METHODS: New patients referred to a dermatology clinic were initially examined by telemedicine and then by a standard face to face consultation. The diagnoses made by each type of consultation were compared and accuracy of telemedicine determined. RESULTS: One hundred and four patients with 135 dermatological conditions were analysed. Seventy five percent of conditions were correctly diagnosed by telemedicine. In a further 7% a differential diagnosis was made, which included the final diagnosis made face to face. In 12%, the diagnosis was incorrect using the telemedicine system, and in 3% no diagnosis was made. Four per cent of diagnoses were only made when the patient was seen face to face. CONCLUSION: This preliminary study suggests that video conferencing equipment can be used with a reasonable degree of accuracy for the diagnosis of dermatological disease.

Adolescent↗

Contact dermatitis from cetostearyl alcohol.

Emulsifiers are an uncommon cause of allergic contact dermatitis. Five cases of allergic contact dermatitis to cetostearyl alcohol are presented. In all five cases, multiple positive reactions to other allergens were present, usually topical corticosteroid creams.

Adult↗

The clinical spectrum of necrotising fasciitis. A review of 15 cases.

BACKGROUND: Necrotising fasciitis represents a spectrum of disease which ranges from fulminant through acute to subacute varieties. While fulminating necrotising fasciitis is a well recognised entity the subacute variety is not. AIM: To assess six years' experience of necrotising fasciitis at Waikato Hospital. METHOD: Cases of necrotising fasciitis were identified from discharge statistics for the period 1990-1995. Records were reviewed for clinical features, predisposing factors, microbiology, histology, treatment and outcome. RESULTS: Fifteen cases were identified of which ten were female. The average age was 55 years (range of 15-92 years). One patient presented with fulminant, eight with acute and six with subacute necrotising fasciitis. Significant blister formation was noted in eight cases. Risk factors were identified in 14 patients including trauma, renal impairment, diabetes mellitus, and various drugs including diclofenac (four patients), naproxen (one patient) and prednisone (two patients). Group A beta haemolytic streptococcus (GABHS) was identified in ten cases. Swab or tissue cultures had the highest yield for isolating the organism. Blood cultures grew GABHS in only three of 12 cases. Eight patients (53%) died. Of the survivors all but one patient required debridement and skin grafting. CONCLUSIONS: Necrotising fasciitis is a clinical spectrum of disease. It affects a wide age group and can have associated morbidities. It is often a fatal disease. Early recognition, high dose antibiotics and surgical debridement are important in the management of the entire spectrum of necrotising fasciitis.

Adolescent↗

Primary school children's perceptions of the effects of sun on skin.

To assess whether young children understand the dangers and results of sun exposure, a novel Draw and Write technique was used to survey a group of 5-8 year old primary school children. One hundred and ninety-four children were invited to draw and write comments to six scenarios involving sun exposure. Of the children surveyed, 84% gave a negative sentiment to sunburn, with only 6% displaying positive sentiments towards sunbathing. Sixty-five per cent of children suggested the use of sun blocks, 69% the use of protective clothing, 45% the wearing of hats and 43% the use of shade as a mechanism for protecting the skin from sun damage. Only 2% of children made any reference to skin cancer. The primary school children surveyed had a good level of awareness of the dangers of sunburn and the need to take appropriate actions to avoid sun damage.

Attitude to Health↗

Multiple medicament allergies in two patients with chronic leg ulceration.

Medicament allergies in patients with chronic leg ulcers is well recognized. In the past, topical antibiotics, rubber additives and wool alcohols have been the most common reported allergens. Allergy to topical corticosteroids has been reported. We document two cases of multiple corticosteroid allergy in patients with chronic leg ulceration.

Administration, Cutaneous↗

Cutaneous adverse drug reactions in a hospital setting.

AIMS: A prospective survey of the number and nature of cutaneous adverse drug reactions in a hospital setting. METHOD: Six month survey of cutaneous adverse drug reactions in hospital inpatients (April to October 1992). All patients were reviewed by a specialist dermatologist who assessed the adverse drug reaction as being: (1) type A adverse reaction (ie, expected, eg, acne vulgaris from systemic steroids; (2) type B adverse reaction (ie, unexpected, eg, allergic reaction; (3) not drug related; and (4) other/do not know. RESULTS: Sixty patients were reviewed; 38/60 patients (63%) had a cutaneous reaction related to their drug therapy or in-patient care. Of these, 7 had a nonallergic adverse drug reaction (type A). A further 31 had a type B adverse reaction: 27 had an allergic reaction to a systemic drug and 4 had an allergic contact dermatitis to a topical agent. 17 patients had cutaneous signs unrelated to their drug therapy, mostly a primary skin disorder (eg, eczema, psoriasis, etc). Of the remaining 5 patients it was not possible to determine the cause of the cutaneous reaction. The most common drugs associated with adverse drug reactions were the penicillin group of antibiotics, followed by frusemide, prednisone, allopurinol and carbamazepine. CONCLUSIONS: Adverse drug reactions are common and may result in additional morbidity to patients. However, only half of the cutaneous adverse reactions seen were secondary to allergy. As the diagnosis of an allergic reaction to drugs may have important therapeutic implications, review by a specialist dermatologist may be indicated.

Adolescent↗

Allergic contact dermatitis to Toxicodendron succedaneum (rhus tree): an autumn epidemic.

AIMS: To document all cases of allergic contact dermatitis (phytodermatitis) due to contact with Toxicodendron succedaneum (rhus tree) presenting to a dermatology clinic during 1993. METHOD: Case-note review of all cases of phytodermatitis attributed to exposure to rhus tree seen during 1993 in a dermatology clinic. RESULTS: Twenty cases of phytodermatitis to T succedaneum were reviewed. Eight patients were females and 12 males with a bimodal age distribution (ten children under age of 15 yr, five adults between 35-45 yr of age). Younger patients presented with facial dermatitis reflecting facial contact whilst playing under rhus trees. Older patients presented largely with a dermatitis affecting the upper limbs reflecting contact whilst gardening (usually pruning). Fifteen out of twenty presented during the months of March through May (ie. autumn), with the remainder presenting in summer (Dec-Feb). The majority of patients required systemic steroids to settle the intense dermatitis. CONCLUSIONS: Phytodermatitis to T succedaneum is not uncommon in New Zealand, particularly during the autumn months. The clinical presentation varies according to the patient's activity.

Adolescent↗