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Biomedical subjects

M Rafii

Publications and source records attributed to M Rafii.

89 records · Page 5Linked to original sources

Pulmonary disorders associated with Sjogren's syndrome.

Pulmonary disorders occur in 25 to 47 per cent of the patients with Sjogren's Syndrome. These are of two types: 1. related to the major connective tissue disorders which commonly accompany this syndrome, and 2. secondary to the peculiar underlying pathology of Sjogren's Syndrome i.e. sicca disorders of the lung. The latter is the more frequent type, occurring mainly in patients with protected sicca complex unaccompanied by a systemic connective tissue disorder, and consists of chronic bronchitis, subsegmental atelectasis, pneumonia, bronchiectasis, lymphoproliferative pulmonary infiltrates and chronic interstitial pneumonitis which may lead to pulmonary fibrosis. 21 cases of Sjogren's Syndrome, 9 of whom had evidence of pulmonary abnormality, are presented, including a case of interstitial pneumonitis leading to diffuse interstitial pulmonary fibrosis. A review of the literature is included.

Adolescent↗

Effect of malnutrition on several parameters of the immune system of children.

In order to study the relationship between nutritional status and immunity, certain biochemical and immunological parameters were examined in 53 children with mild or severe malnutrition and 35 normal controls. The levels of hemoglobin, total serum protein and complement (C'3) were not affected by malnutrition. There was a significant depression of serum albumin, transferrin and ceruloplasmin in the severely malnourished children. Serum IgM, IgG and IgD were normal in both malnourished groups. The level of serum IgA was elevated only in the severely malnourished children. The proportion of B cells was the same in all groups; howver, the frequency of T cells was reduced in the severely malnourished cases.

B-Lymphocytes↗

Peptic ulcer in Iranian children.

Thirty cases of peptic ulcer were presented, all of which were diagnosed in accordance with strict radiological criteria. Upper abdominal pain was the most common presenting symptom. Hemorrhage occurred in 36.6% of the cases, and 16.6% suffered from melena and hematemesis requiring transfusions on admission. The only fatal case was due to perforation of a duodenal ulcer. Almost all of the children came from lower income groups and were inhabitants of Tehran or the suburbs. The incidence of peptic ulcer in Iranian children is 15.1 per ten thousand with 60% of the cases occurring in females. This suggests that peptic ulcer may be more common in Iran when compared to Europe or the United States and taht more cases occur in female children in Iran.

Adolescent↗

Computerized tomography in diagnosis of pelvic abscess in spinal-cord-injured patients.

Twenty-four spinal-cord-injured patients with pressure sores, and suspected of having other complications were studied by CT, gallium scanning, and ultrasonography. CT was found to be by far the modality of choice for evaluation of the extent and depth of the pressure sore, assessment of the thickness of fibrous tissue scar alongside its boundaries and at its base, detection of associated peri-pelvic and intra-pelvic soft tissue abscesses, sinus tracts and osteomyelitis of the pelvic bones.

Abscess↗

Computerized tomography in diagnosis of compression of the common peroneal nerve by ganglion cysts.

A 48-yr old man noted gradual onset of pain, and paresthesia on the lateral aspect of his right leg. The findings were suggestive of S1 root compression. CT of spine was normal. Physical examination revealed a small mass overlying the right fibular head. CT revealed this to be a cystic mass. At surgery a ganglion cyst compressing the common peroneal nerve was found. Peripheral nerves may be compressed by ganglia producing a syndrome mimicking central nerve root compression. CT is the modality of choice for detection of these lesions.

Hip↗

Computerized tomography of the Cupid's bow contour of the lumbar spine.

The inferior endplates of the third, fourth, and fifth lumbar-vertebral bodies frequently have paired parasagittal concavities when viewed in the frontal projection. In the lateral projection, these concavities lie posteriorly and are superimposed. This has been called Cupid's bow contour of the spine. On CT, Cupid's bow is visualized in an axial plane as two rounded relatively well-circumscribed areas of hypodensity rimmed by apparant osteosclerosis in the posterior half of the vertebral bodies. This, on occasion, may resemble metastasis or other pathology of the spine. The CT features, however, once appreciated, are characteristic of this normal variant, helping to distinguish it from other contour deformities of the vertebrae having clinical significance. The CT features are described and the incidence is discussed in 100 patients.

Adolescent↗

Computed tomography in localization of foreign bodies lodged in the extremities.

Surgical removal of foreign objects (FO) lodged in the body may be difficult because of uncertain 3-dimensional localization on conventional roentgenograms. Furthermore, low-density FO may not be detectable on roentgenograms. CT was performed in 8 patients with FO lodged in the extremities, and was found helpful because, (1) it detected 4 low-density FO's missed on roentgenograms, and (2) it facilitated surgical removal by displaying the precise 3-dimensional location of these objects.

Adult↗

[Synovial hemangioma within Hoffa's fat pad as the cause of anterior knee pain. 2 cases within a family and review of the literature].

An 18 years old man and his younger sister suffered from anterior knee pain. Cause is a soft tissue tumor located within Hoffa's fat pad however in both cases. The tumor has been excised and the histological examination demonstrated the diagnosis synovial hemangioma. A literature search shows that synovial hemangiomas are rare soft tissue tumors. They mainly involve the knee joint. Mean age is the second decade of life and most authors observed severe degenerative changes in the involved knee joint. There are no reports about familiar accumulation within the literature. Familiar accumulation of synovial hemangiomas however have been described for cerebral, skin and hepatic manifestations but not for synovial hemangiomas.

Adipose Tissue↗

Radiation induced fractures of sacrum: CT diagnosis.

Sacral insufficiency fracture due to bone atrophy may develop as a complication of irradiation of pelvic malignancies. Pain is the presenting symptom and the clinical diagnoses most often considered are recurrence of the original malignancy and metastatic disease. Computed tomography provides the most specific information helpful for the detection of these fractures and for exclusion of recurrent malignancy.

Aged↗

Comparison of conventional and computed arthrotomography with MR imaging in the evaluation of the shoulder.

To compare conventional arthrography and computed arthrotomography (CAT) with magnetic resonance (MR) imaging in the evaluation of the shoulder, we studied 18 patients who underwent conventional double contrast arthrography and CAT, and T1-, balanced, and T2-weighted MR imaging. The arthrograms were independently reviewed by two of the authors and the MR images were independently reviewed by three other authors in a systematic fashion with the aid of a prewritten evaluation form. The findings were compared among reviewers and between imaging methods. We found MR comparable to conventional arthrography in the evaluation of the rotator cuff; however, MR also enabled evaluation of tendonitis, which could not be accomplished with conventional arthrography. Because of MR's superior soft tissue imaging capability, we were able to stage the impingement syndrome. Magnetic resonance also allowed evaluation of the glenoid labrum and capsuloligamentous structures and assessment of instability in a fashion similar to CAT. In most cases, information obtained from MR equaled or exceeded that obtained from conventional arthrography and CAT. With refinement in technique and increased experience, we believe that MR may replace arthrography in the evaluation of the shoulder.

Adolescent↗

Condensing osteitis of the clavicle: MRI.

PURPOSE: Condensing osteitis of the clavicle is a rare benign disorder, seen exclusively in women and characterized by expansion and sclerosis of the medial end of the clavicle. The aim of this study was to evaluate the MR findings of this disorder. METHOD: MR images, obtained in four patients with evidence of condensing osteitis of the clavicle based on plain radiographs and clinical symptoms, included pre- and postcontrast T1 SE sequences, T2 SE images, GE images. RESULTS: MR images revealed consistent hypointense areas on T1-weighted SE images, corresponding to regions of clavicular sclerosis (n = 4). T2-weighted SE images showed signal characteristics ranging from low intermediate signal intensity in regions of sclerosis (n = 4). T2-weighted GE images revealed moderate to high signal intensity presumably related to bone marrow edema (n = 2). Contrast-enhanced T1-weighted SE images were characterized by mild to extensive intraosseous and periosseous enhancement of signal intensity (n = 2). CONCLUSION: MRI in cases of condensing osteitis of the clavicle reveals variable findings perhaps indicative of different stages of activity in this disease.

Adult↗

Computed tomography (CT) arthrography of shoulder instabilities in athletes.

Sixty professional and recreational athletes underwent CT arthrography of the shoulder for evaluation of suspected shoulder joint derangement. These athletes, 46 males and 14 females ranging in age from 15 to 60 years (mean, 32 years), all had persistent pain that interfered with their sports activity and was resistant to conservative treatment. Seventeen patients had shoulder instability based on clinical manifestations and CT arthrographic findings. An additional five patients, also based on clinical manifestations and CT arthrographic findings, were considered to have an unobtrusive degree of anterior joint laxity. Patients with anterior instability (20 cases) all had an anteroinferior tear or detachment of the glenoid labrum, as well as some violation of the insertion of the joint capsule onto the scapula. Those with posterior instability (two cases) had a combination of labral and capsular tears. Two other major patterns of labral tears, both unaffiliated with shoulder instability, were identified. These included total or partial detachment of superior segments of the labrum, and anterior labral tears at the midglenoid level. Moreover, various degrees of labral attenuation (or, less often, enlargement), osteophyte formation, and alterations in articular cartilage were observed. Surgical correlation was obtained in 25 patients, with 95% accuracy of CT arthrographic findings. CT arthrography is a minimally invasive and highly accurate technique for investigation of glenohumeral derangement. Specifically, the extent of pathologic changes associated with instability can be determined and differentiated from other intraarticular causes of incapacity, such as labral tears caused by throwing, or degenerative changes.

Adolescent↗

Acute traumatic fibular bowing associated with tibial fractures.

Acute traumatic fibular bowing associated with angular fracture of the tibia was observed in three young adults. The fibular bowing may have had a negative effect on the healing of the tibial fracture by transmitting tension through the interosseous membrane, thereby preventing proper reduction of the tibial fracture fragments and delaying the union.

Adult↗