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Biomedical subjects

M Reither

Publications and source records attributed to M Reither.

50 records · Page 3Linked to original sources
PubMed1979

[Dose and time-saving fluoroscopy by means of immediate reproduction of a high-quality stored image (author's transl)].

A report is given on a special unit for use with an X-ray television chain, which permits the immediate reproduction of views stored during fluoroscopy, and thus speeds up the establishment of a reliable diagnosis. The stored images are also available during the examination. They clearly show whether the phases of functional processes needed for assessment purposes are actually represented. The result is that additional radiography is avoided, the patient subjected to less exposure the examination procedure shortened. A comparison with the corresponding 100 mm image intensifier views in clinical examples shows that the quality of the stored image is completely adequate for the establishment of the diagnosis.

Crohn Disease↗
PubMed1978

[Exogenous allergic alveolitis during childhood (author's transl)].

Four children aged 31/2 to 13 years, who developed allergic alveolitis as a result of antigenic exposure in a domestic situation are described. The clinical symptoms consisted of gradual onset of increasing dyspnoea, chronic cough and weight loss. Lung function tests showed characteristic reduction in vital and diffusion capacity. Serologically, antibodies against animal antigens were demonstrated in all patients. Radiologically there were pronounced reticular changes in both lungs affecting mostly the middle and lower zones. Occasionally there were miliary and sometimes confluent shadows. In differential diagnosis, virus infections, pneumocystis carinii, fungus infections, dermatomyositis, sarcoidosis and tuberculosis had to be considered. Apart from a short course of steroid treatment, it is necessary to make certain that the children are no longer exposed to the causal antigen. Under these conditions the prognosis is good, but otherwise the disease, as in adults who are continuously exposed to the antigen, results in pulmonary fibrosis.

Adolescent↗
PubMed1978

[Roentgen diagnosis of necrotizing enterocolitis in the newborn (author's transl)].

The necrotizing enterocolitis in the newborn is a life threatening disease which is probably induced by stress to the mother or child. Mostly it occurs in the second week of life. After initial non specific symptoms rapid detoriation occurs with distended abdomen, blood diarrhea, bileous vomiting, rapid impairment, septicemia and shock. Careful clinical observation and interpretation of the roentgen signs as intramural gas collection in distended bowel loops (pneumatosis intestinalis) with air fluid levels, gas collection in the portal vein, ascites, free air in the abdomen after viscus perforation can improve the unfavorable prognosis when the correct diagnosis is made and adequate therapy is started in time.

Enterocolitis, Pseudomembranous↗
PubMed1978

[Alterations of pulmonary patterns in roentgenographic follow up studies in respiratory distress of newborns and prematures (author's transl)].

The most common causes of respiratory distress in the newborn and the frequently rapidly changing pulmonary pattern in the follow up studies are presented. Various degrees of the hyaline membrane disease and bronchopulmonary dysplasia are demonstrated as well as the different changes of the pulmonary pattern in controlled and assisted ventilation, recurrent atelectasis, dystelectasis, emphysema, pneumothorax and pneumomediastinum. Chest film follow up series are demonstrated. The differential diagnosis includes pulmonary aspiration syndrome, the neonatal pneumonia and emergency cases in pediatric surgery (here an example of a congenital diaphragmatic hernia).

Bronchi↗
PubMed1977

[Increased occurrence of mycoplasmal pneumonia: radiologic appearance and observation of the development of the disease in children (author's transl)].

The epidemic occurrence of mycoplasmal pneumonia in children was reported. It composed 8% of all cases of pneumonia during 1975 occurring in the area served by the University Pediatric Hospital in Giessen. It should be noted that the cases were distributed throughout the year and that one fourth of the patients were small children. The diversity of the radiologic appearance with primarily interstitial-alveolar lesions in the lungs was explained in more detail. Observations of the course of the disease indicate that the illness can be recurrent; the course can be complicated as a result of immunosuppression through a primary illness which is already present, in this case an acute lymphoblastic leukemia.

Child↗
PubMed1975

Partial monosomy 13 as the result of a balanced translocation 3/13 pat.

In a 4 1/3-year old girl we found the karyotype 45, XX, del13(pter yields q12). The father showed a balanced translocation 3/13 (karyotype: 46,XY,t(3;13) (p27;q12). Psychological investigation of the patient revealed almost normal intelligence (DQ91). Clinical symptoms were: low birth weight, growth retardation, dolichocephalus, microgenia, antimongoloid slant of the eyes, edema on hands and feet, strabismus convergens, clubfoot (left), slight decrease in IgA and IgM.

Aneuploidy↗
PubMed1975

[Dermatoglyphics in Noonan's syndrome (author's transl)].

Dermatoglyphics in Noonan's Syndrome A dermatoglyphic analysis has been carried out in 7 boys and 5 girls affected by Noonan's syndrome. No deviation from the general population values was found with respect to individual quantitative value, A line termination, absence of C line, a-b ridge count, hypothenar patterns, and presence of p proximal triradius on soles. Whorls were however increased on fingertips and the axial triradius t, as in Turner's syndrome, was in 21% of the cases in position t' or t".

Dermatoglyphics↗
PubMed1975

Cytosome morphology and distribution of generalized ceroidlipofuscinosis in a twenty-eight month old boy with normal myeloperoxidase activity.

A brain biopsy obtained from a twenty-eight month old boy with ceroidlipofuscinosis was studied by light and electron microscopy. There were widespread intracellular deposits of autofluorescent material taking the fat stains. Cytoplasmic inclusions were plentiful in neurons, astrocytes, oligocytes, M cells and vascular elements. Their substructure ranged from that of variably dense aggregates of essentially homogeneous or granular appearance to that of miscellaneous collections of lamellar pairs and/or tubular structures of variable length. Stacks of 2 to 4 linear profiles with a curved outline were rarely seen and then almost exclusively inside cytosomes of endothelial cells. Similar observations were made in peripheral nerve, skin and liver biopsies. The granules of peripheral blood neutrophilic leukocytes were unremarkable. A small percentage of lymphocytes contained granular cytoplasmic bodies not unlike those known to be an ordinary feature of some lymphocytes of the average blood sample. However, a certain resemblance between these bodies and some of the cytosomes seen in the patient's tissues was also apparent. Myeloperoxidase activity was tested with paraphenylenediamine and was found to be normal on two occasions. The patient's age, cytosome morphology and distribution and results of peroxidase assay add special interest to this case of generalized ceroidlipofuscinosis. However, none of these features, either singly or in combination, warrants creation of a distinct subtype within this group of disorders. Myeloperoxidase deficiency is probably just another phenotypical marker of some patients with generalized ceroidlipofuscinosis rather than the genetic defect of Batten disease.

Age Factors↗
PubMed1975

[Genetic studies in hypoplastic left heart syndrome (author's transl)].

The families of the 18 patients with hypoplastic left heart syndrome (HLH), who died in the Universitätskinderklinik Erlangen between 1967 and January 1974, have been investigated. There was no consanguinity of the parents. Only one sib has died of a cardiac failure which possibly could have been HLH. Therefore it could be excluded that HLH is an autosomal-recessive disorder. The overall incidence of cardiac failure in the sibs of patients was 3. Most of the patients with HLH have been born in June-August and December-January. Environmental factors seem to be of importance in the genesis of HLH. Our results suggest multifactorial inheritance of the hypoplastic left heart syndrome.

Abnormalities, Multiple↗
PubMedDate not supplied

[Stüve-Wiedemann syndrome in two siblings: focusing on a male patient with the longest actual survival rate].

BACKGROUND: We report on two siblings with Stüve-Wiedemann syndrome (SWS). The older patient, a 16-year-old boy, is -- as to our knowledge -- the longest-term survivor of this syndrome worldwide. The younger sister with the same clinical and radiographic findings died at the age of 10 months. DEFINITION: Characteristic clinical symptoms are: muscular hypotonia, camptodactyly; respiratory insufficiency, swallowing difficulties; reduced sweating with heat intolerance, episodes of hyperthermia. Typical radiographic findings are: progressive bone bowing, unusual bone fractures, abnormal trabecular pattern, middle face hypoplasia. GENETICS: The SWS is identical with the Schwartz-Jampel syndrome (SJS) type 2, which is gene-located on chromosome 1. So far further genetic details of the SWS can be expected in the near future. The genetic transmission is autosomal recessive. In inbred high risk populations the occurrence of the SWS is increased. THERAPY: For the present only symptomatic therapy is available: extended intensive care during infancy, supportive pediatric orthopedics later on.

Abnormalities, Multiple↗
PubMedDate not supplied

[Ultrasound screening of newborn infants. Uses and role in routine diagnosis].

The results of sonographic brain, renal and hip studies in 3396 clinically healthy, consecutive newborns during two and a half years are correlated to various anamnestic, clinical and ultrasound data. In the nearly sex-matched babies there were 4.2% anomalous brain studies, 4.4% renal studies followed by further diagnostic and therapeutic steps, and 7.4% right-sided and 9.7 left-sided hip dysplasias. A statistically significant dependence of neurosonographic findings from the delivery mode and a significant amount of renal abnormalities in turkish babies and infants of other nationalities were remarkable. The ultrasound hip studies confirmed the significantly higher rate of left-sided hip dysplasias in baby girls found in other studies. 80% of the initially diagnosed hip dysplasias type IIa according to Graf matured within the first six weeks of life. After six weeks there remained 4.2% hip dysplasias type IIg to type IV (luxation) which were treated. Breech-delivered infants, especially if manually handled, had delayed hip maturation. In turkish babies we found relatively more normal hip exams. Hip symptoms clinically proved correlated significantly with pathologic ultrasound hip studies. Statistically proved correlations between initially measured and follow-up alpha- angles provide the possibility to prognose the hip maturation using a regression-equation. Whereas the value of an ultrasound brain-screening is still in discussion, the authors believe that the introduction of a general ultrasound-screening of the urinary system and hips is mandatory.

Brain↗
PubMedDate not supplied

[Indications for proton spin tomography in central nervous system diseases in childhood. A 4-year experience report on 164 cases].

1. Magnetic Resonance Tomography (MRT) is the method of choice for precise, comprehensive and reproducible imaging of congenital malformations and space occupying lesions. 2. MRT indicates inflammatory processes of the CNS earlier than CT by which extension and localization are visualized more precisely. MRT gains particular importance for follow-up studies because there is no radiation burden. In cases of disseminated inflammatory lesions or concerning early diagnosis of Herpes-encephalitis an exact and rapid diagnosis is possible. 3. In patients suffering from convulsions with or without focal lesions in EEG MRT instead of CT should be applied as MRT allows three-dimensional imaging not influenced by bone artifacts. 4. CT is superior to MRT if small calcifications or acute hemorrhage are looked for. MRT enables us to differentiate several stages of bleeding. 5. In patients with cerebral AV-malformations angiography can be replaced by MRT. However, angiography is indispensable for small aneurysms and AV-malformations in the spinal canal. 6. Due to high soft tissue contrast MRT is the imaging modality of choice in patients with metabolic and degenerative diseases and disturbances of brain maturation. 7. In infants sonography should be done first and supplemented by MRT and/or CT.

Adolescent↗