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Biomedical subjects

M Renaer

Publications and source records attributed to M Renaer.

At least 19 recordsLinked to original sources
PubMed1997

Pain sensitivity of and pain radiation from the internal female genital organs.

The aim of this study was to determine the sensitivity and the localization of pain from the internal female genital organs. In 28 women undergoing a ring sterilization, the internal genital organs were pinched with a 3 mm forceps and the pain sensitivity and localization were recorded. Pain localization was vague, and pinching of the medial and distal end of the oviduct, or of the anterior, posterior or left or right uterosacral ligament could not be discriminated. The sensitivity of the pouch of Douglas and of the uterosacrals was greater than of the oviduct, uterus or ovaries. Small typical endometriotic lesions were specifically more painful. The pain from the uterus was felt mainly in the hypogastric region. The oviducts and ovaries radiated mainly to the iliac fossa, whereas pain stimulation of the uterosacrals and pouch of Douglas was felt predominantly in the perineal-perivulvar-perianal region. Radiation to the lower back was rare and never occurred in isolation.

Female↗
PubMed1995

[Considerations on education and formation in health care ethics in Belgium].

Codes of medical ethics summarize the most important duties of the medical profession; but the field of medical ethics encompasses more problems than are treated in the codes, and the management of many health care problems necessitates the collaboration of non-medical personnel. This state of affairs has led to the broader notion of health care ethics. All important problems of health care have ethical aspects, and during the last decennia progress in many branches of biology and medicine has brought with it new ethical problems. This renders teaching and education in health care ethics all the more important. The time allotted to the formal teaching of health care ethics is very limited. Therefore, whoever is responsible for teaching and education of medical students should contribute by his(her) example, his(her) advice and supervision, where appropriate, to the ethical education of the younger generation. As new problems will surely arise during the later professional life, their explanation and discussion should, more than is currently being done, be integrated in the programs of continued medical education.

Belgium↗
PubMed1989

History of prenatal care in Belgium.

The history of the national mother and child care organization is reviewed up to 1980. The organisation originates in the efforts made during the First World War to provide food for mothers and children. Free prenatal visits have been organized since 1919. Among other activities, an extensive system of home visiting has been provided. The special program of prevention of preterm deliveries is an example of more recent actions focusing on high-risk groups.

Female↗
PubMed1983

Thrombosis of the right umbilical artery, presumably related to the shortness of the umbilical cord: an unusual cause of fetal distress.

This case report concerns a late pregnancy complication, clinically apparent as severe variable decelerations in the first stage of labor. Emergency cesarean section delivered a mildly asphyxiated full-term newborn infant. Examination of the umbilical cord revealed a thrombus of the right umbilical artery, near the fetal side, confirmed by histological examination. The total length of the umbilical cord, only 30 cm, was below the limit necessary for uncomplicated delivery of the fetus near term. Transient stretching during fetal descent is thought to be responsible for constriction of the umbilical arteries, blood flow sludging and thrombosis. Although only a few cases have been reported, thrombosis of the umbilical vessels has to be considered whenever the fetal heart rate pattern shows unexplained variable decelerations.

Adult↗
PubMed1982

Thyroid function in patients with hyperemesis gravidarum.

An increased free thyroxine (T4) index was observed in 73% of 33 consecutive pregnancies complicated by severe hyperemesis gravidarum. The free triiodothyronine (T3) index was increased in only four of 11 hyperthyroxinemic patients. In five hyperthyroxinemic patients tested, no increase in serum thyrotropin was observed after the injection of thyrotropin-releasing hormone (THR). Goiter, exophthalmos, or previous history of hyperthyroidism was absent in all patients. The thyroxinemia returned to normal in one to several weeks, whether or not it was treated with antithyroid drugs. The thyroid function during the period of hyperemesis had no influence on the subsequent rate of abortion or duration of pregnancy. A lower birth weight, however, was observed in children born to hyperthyroxinemic mothers. Hyperemesis gravidarum should be included in the differential diagnosis of elevations in free T4 index during pregnancy and included in the differential diagnosis of hyperthyroidism.

Abortion, Spontaneous↗
PubMed1982

Decidual vasculopathy and extensive placental infarction in a patient with repeated thromboembolic accidents, recurrent fetal loss, and a lupus anticoagulant.

Evidence exists of an association between the presence of a "lupus" anticoagulant in plasma, recurrent fetal loss, and repeated thromboembolic accidents, also in the absence of systemic lupus erythematosus. Presented is an example of this association, with morphologic and biologic studies to elucidate its pathogenesis. In the case reported, the placenta showed massive infarction. In the spiral arteries of the basal plate of the placenta, lesions of intimal thickening, fibrinoid necrosis, acute atherosis, and intraluminal thrombosis were observed. The plasma of the patient contained a lupus anticoagulant and inhibited the formation of prostacyclin by rat aortic rings. Vascular production of prostacyclin is a major natural defense mechanism against thrombosis. Lack of generation of prostacyclin may account for the decidual vasculopathy and consequent placental infarction and for the generalized thrombotic tendency of some patients with lupus anticoagulant.

Abortion, Habitual↗
PubMed1980

Origin of peritoneal fluid in women: an ovarian exudation product.

The volume of peritoneal fluid was measured after laparoscopic aspiration in 303 women. Contamination with blood was estimated at 4.2 per cent by haemoglobin assay. In 120 women with regular menstrual cycles, the volume of peritoneal fluid increased progressively during the follicular phase, was highest during the early luteal phase (20.0 +/- 6.3 ml) and declined thereafter. In 89 women with moderate and mild endometriosis the amounts of peritoneal fluid were similar, but 9 women with severe endometriosis had lower (P less than 0.05) volumes during the luteal phase. Women with inactive ovaries had uniformly low amounts of peritoneal fluid: 4.2 +/- 2.3 ml in 31 women taking combined oral contraceptive pills; 4.7 +/- 5.8 ml in 17 women taking 5 mg of lynoestrenol daily and 1.2 +/- 1.9 ml in 20 postmenopausal women with an inactive endometrium. In contrast, two postmenopausal women with proliferative endometrium had 7 and 10 ml of peritoneal fluid. Women with active ovaries, 5 with absent or distally occluded Fallopian tubes and 7 without a uterus had normal amounts of peritoneal fluid. The volume of peritoneal fluid was not affected by pelvic varicose veins, a visible corpus luteum or an ovulation stigma. Peritoneal fluid appears to be predominantly an ovarian exudate, neither an exudate from the pelvic peritoneum nor a tubal secretion.

Ascitic Fluid↗
PubMed1980

Fetal growth retardation and the maternal arterial supply of the human placenta in the absence of sustained hypertension.

In five patients with fetal growth retardation in pregnancies with no or only a moderate and transient rise in blood pressure, vascular lesions in the placental bed spiral arteries were found. These lesions are characterized by less well developed physiological morphological changes, by extensive intimal thickening, by fibrinoid degeneration of the media and by acute atherosis. the recurrent fetal growth retardation in these pregnancies may be the first clinical manifestation of underlying reno-vascular disease.

Adult↗
PubMed1978

Pain in gynecologic practice.

This paper has given a general discussion of the spectrum of pain complaints presented to the gynecologist. Specific information about pain sensation and localization has been reviewed together with the gynecologic causes of acute abdominal pain. Chronic pain has been classified as episodic or continuous, and the causes, mechanisms, diagnosis and treatment of episodic and chronic pelvic pain have been presented. The concluding remarks have outlined some diagnostic considerations for the patient with chronic pain. (The interested reader will find more extensive information on these subjects in the articles listed in the bibliography.).

Acute Disease↗
PubMed1977

[Radioimmunoassay of HCG and HCG beta in blood during pregnancy and trophoblastomas].

This work was carried out on 151 estimations of the radioimmune levels of hCG-hCG beta in the first half of normal pregnancy and 390 levels estimated in 10 molar pregnancies, in 4 choriocarcinomata following moles and 1 primary choriocarcinoma of the ovary using homologous hCG beta. In normal pregnancy the level of hCG-hCG beta rises rapidly. The levels are highest between the 8th and 9th weeks of pregnancy, and then gradually decrease. In active molar pregnancies the levels of hCG-hCG beta in the plasma are significantly higher than those found in normal pregnancies of the same gestational age. When the outcome is going to be favourable the levels drop progressively. Complete absence in peripheral blood is usually found about 14 weeks after a mole has been expelled or evacuated. In choriocarcinomata, if the level of hCG-hCG beta rises it is a certain sign of reactivation of the tumour.

Adult↗
PubMed1976

Massive feto-maternal hemorrhage as a cause of perinatal mortality and morbidity.

11 cases of massive feto-maternal hemorrhage (FMH) detected at the Leuven Blood Transfusion Center are described. Based on these case reports, a review is given of the various theoretical and practical problems related to this complication, e.g. the relative frequency of perinatal mortality and morbidity due to massive FMH, the causes and pathogenesis, the symptoms and diagnosis, the clinical varieties, and the pathophysiology as seen in the fetus and newborn. Finally, the indications for looking for large FMHs are described, and the therapeutic implications when this complication is discovered.

Adult↗