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Biomedical subjects

M Respondek-Liberska

Publications and source records attributed to M Respondek-Liberska.

9 recordsLinked to original sources
PubMed1999

[Analysis of perinatal death at the Institute of the Health Center of the Polish mother in 1995, 1996 and 1997. The reason for making changes in the accountability for perinatal death].

Perinatal death's causes of fetuses and newborns from single and twin pregnancies delivered at the PMMHI from 1995-1997 were discussed. Data from the Pathology Department were analysed and compared to information regarding prenatal US + ECHO diagnoses coming from the Department for Diagnoses of Congenital Malformations at the PMMHI. The most frequent cause of death of fetuses and newborns from single pregnancies were congenital malformations (42%). In twins there prevailed such typical for multiple pregnancies' death causes as TTTS (27%), intrauterine demise of one of the twins (17%). Premature labor occupies the second most frequent cause of death both in single and multiple pregnancies. Most of perinatal deaths may be predicted prenatally by means of ultrasound and fetal echocardiography.

Catchment Area, Health↗
PubMed1998

[The significance of cardiography in the diagnosis of cardiac ectopia of the fetus].

Retrospective analysis of echocardiographic examinations of 7 fetuses with ectopia cordis was presented. The majority of abnormalities were found in low risk pregnancies. There was only one case of isolated ectopia cordis with normal heart anatomy and no extracardiac malformations. There was no survival. Theoretically the prenatal diagnosis of isolated ectopia cordis may help to choose the proper term, place and method of delivery and also to plan the optimal care of newborn. Parents should be counseled about the prognosis in such cases, at the tertiary center, after detailed fetal echocardiography.

Adult↗
PubMedDate not supplied

Can we suspect fetal down syndrome by heart evaluation during the second half of pregnancy?

UNLABELLED: Thirty fetuses with Down syndrome, who had detailed fetal echocardiography and sonography at the tertiary center with videotape recordings, were retrospective analyzed by one observer with a specially prepared flow sheet. The mean gestational age of the fetuses at the time of the study was 31 +/- 5.6 (minimum 21, maximum 39) weeks. The 'main' fetal abnormalities were congenital heart defect (CHD): in 13 cases (43.3%) an abnormal 4-chamber view was recorded, including 6 cases (20%) of isolated CHD and 7 (23.3%) of coexisting CHD + extracardiac malformation. Of the 13 cases of CHD, there were 12 cases of atrio-ventricular canal and 1 case of ventricular septal defect. Normal heart anatomy was recorded in 17 cases (56.7%), including 2 with tricuspid value regurgitation. From the videotape recordings also some 'minor' abnormalities were noticed in a few cases such as: femur length shortening; sandal gap; pericardial effusion; macroglossia; echogenic bowel; absent diastolic flow in the umbilical artery, and others. The prevalence of CHD in the study group was similar to the prevalence of CHD in the comparison group of 20 newborns with Down syndrome, born during the same period of time at the same institution, who had not had prenatal scanning at all (chi2, p > 0.05). CONCLUSIONS: (1) the main 'major' abnormality which might be detected in a fetus with Down syndrome after 20 weeks of pregnancy is CHD, which was presented in 43.3% of this series; (2) the presence of any extracardiac malformation should prompt the sonographer for detailed heart evaluation, and (3) fetal echocardiography may increase the accuracy of 'genetic sonogram' in Down syndrome.

Adult↗
PubMedDate not supplied

Isolated, persistent functional tricuspid valve regurgitation in a fetus with normal heart anatomy (and no extracardiac malformation). Case report.

Functional fetal tricuspid valve regurgitation was diagnosed by echocardiography at 27 weeks of gestation as an isolated anomaly with a maximum velocity of the regurgitation jet of 3 m/s. This was also observed at 30, 32 and 35 weeks of gestation and at term. Just after delivery pneumonia was diagnosed in the newborn baby based on clinical symptoms, chest X-ray and laboratory findings. To date persistent fetal tricuspid valve regurgitation has not been described in the literature on normal fetal heart anatomy. Various etiologies and possible pathomechanisms are discussed.

Adult↗