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Biomedical subjects

M Rethman

Publications and source records attributed to M Rethman.

11 recordsLinked to original sources

Statistical tests.

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Data Interpretation, Statistical↗

Controlled-release periodontal chemotherapy: the evolution of antimicrobial delivery systems.

Bacterial plaque contributes to the development and progression of periodontal diseases. Therefore, therapeutics designed to stop or slow periodontal destruction must limit or eliminate the deleterious effects of plaque. Despite the recognized beneficial effects of in-office surgical and nonsurgical periodontal therapies and home mechanical plaque control, antimicrobials have been used locally, systematically, or in combination to limit plaque activity. This article discusses a new, localized antimicrobial delivery method. The technique discussed employs an ethylene/vinyl acetate copolymer, containing tetracycline hydrochloride. Description of this polymeric fiber, indications for its use, placement technique, patient education, the role of auxiliaries, and practice management aspects are reviewed. The future potential of sustained-release local pharmaceutical devices is addressed.

Anti-Bacterial Agents↗

Oral irrigation in the treatment of periodontal diseases.

Conceptually, supragingival and subgingival irrigation are techniques that may assist conventional therapy in the treatment and maintenance of periodontal patients. However, the dental literature contains diverse data on the efficacy of oral irrigation, and this variability leads to considerable confusion regarding its utility. This review attempts to place in perspective the advantages and disadvantages of supragingival and subgingival irrigation. Recommendations for use of irrigation therapy are based on the results of published clinical trials and are discussed herein. Shortcomings of comparative study designs are also noted to provide a context for decision making by clinicians.

Clinical Trials as Topic↗

The Computer-Assisted Postmortem Identification (CAPMI) system: sorting algorithm improvements.

Refinements to the original Computer-Assisted Postmortem Identification (CAPMI) software algorithms and general data handling were suggested as a result of observations made following the Gander plane crash of 1985. The presence of highly fragmented and scattered remains following most plane crashes suggested that changes to procedure might improve CAPMI performance for use in these types of disasters. A total of 162 ante- and postmortem dental records which had been used successfully to identify victims of the Gander disaster were coded for anonymity and used for this investigation. Changes in data construction and management were made to CAPMI, according to concepts which were thought might improve system performance, and tested. Although most tested techniques improved CAPMI performance, the data suggested that replacement of "virgin" chartings with "data unknown" results in improved performance of CAPMI largely independent of other factors. Of 162 possible record matches, the original algorithm successfully listed the true record match in the top 20 possibilities 74% of the time; the tested variations on the original algorithm yielded results across a range of 38 to 83% successes, with most techniques performing better than the original algorithm. Results of this investigation have been incorporated into improved CAPMI procedures and software.

Accidents, Aviation↗

The Computer-Assisted Postmortem Identification (CAPMI) System: a computer-based identification program.

The Computer-Assisted Postmortem Identification (CAPMI) system was developed at the U.S. Army Institute of Dental Research to facilitate rapid identification of human remains. The increasing requirement for dental based identification of high-energy fatalities and decomposed remains has dovetailed with the development of computer capabilities permitting automation of most of the highly repetitive chart-by-chart screenings characteristic of traditional identification taskings. This report summarizes the concepts upon which CAPMI is based, describes how it works, and reviews suggested applications and limitations. CAPMI software is available to governmental, civic, or humanitarian organizations at no cost.

Dental Records↗

Diagnosis of bone lesions by subtraction radiography.

Examiner diagnostic accuracy and response times were compared using subtraction and conventional radiography in a dog model. Osseous lesions were induced interproximally and through the mandibular buccal bone interradicularly and radicularly. Standardized preoperative and postoperative conventional radiographs of the induced lesions were compared to subtraction images of the same sites by 11 dentists. Examiners using the subtraction technique demonstrated improved diagnostic performance (P less than 0.001) and response times (P less than 0.001). Additionally, this method yielded a 30% reduction in equivocal diagnostic decisions. Data from this study suggest that subtraction radiography is a sensitive and accurate method to detect osseous lesions associated with periodontal diseases.

Alveolar Process↗