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Biomedical subjects

M Revol

Publications and source records attributed to M Revol.

At least 73 records · Page 4Linked to original sources

[Free-tissue transfer in plastic surgery (emergencies excluded). Apropos of a 10-year experience].

Over a period of ten years the authors have performed 176 elective free tissue transfers. Flaps used were 99 latissimus dorsi, 46 chinese forearm flaps, 12 fibula, 6 toes, 5 omentum, 4 parascapular, and 4 others flaps. Recipient sites were lower limbs in 106 cases, head and neck in 50 cases, forearm and hand in 13 cases, thorax, abdomen, and buttocks in 7 cases. The overall failure rate was 5.7 per cent. Analysis of these failures taught us some original principles. Among these principles, the risk of vascular thrombosis is very important when a venous graft is performed on one end of the artery of a low blood flow flap such as chinese forearm or fibular flaps when the other end of this artery is ligated. When such a graft is done we think that the best way to avoid thrombosis is to suture the other end of the flap artery to a recipient vessel which can be even the distal end of the flap vein itself. Pretransfer expansion of a latissimus dorsi flap was successfully performed in 4 cases. Migrating semi-free flap method, in which the vascular pedicle of a flap is temporarily sutured to recipient vessels located far from the defect, was performed in 12 cases, in most cases on lower limbs where this method constitutes a modern variant of the cross-leg. Folded free-flap method, in which a flap is folded on itself during some days before excision of the recipient site, was performed in 14 cases. Analysis of this series also allowed us to review in detail our usual strategic principles for vascular anastomoses in the head and lower limbs.

Adolescent↗

[Use of the free latissimus dorsi flap in the reconstruction of extensive orbital exenterations].

The authors present the use of a free latissimus dorsi myocutaneous flap for closure of large orbital exenterations. Five cases illustrate different tumor involvements and coverage possibilities. Several technical details are studied. The vascular anastomoses are performed on cervical vessels: external carotid artery internal jugular vein. The latissimus dorsi myocutaneous flap is particularly suited for reconstruction of large facial soft tissue defects around the orbit when obliteration of the orbital cavity and restoration of deficient facial skin are necessary with correct morphological results.

Anastomosis, Surgical↗

MRI in Sturge-Weber syndrome.

Five children (3 girls, 2 boys, aged from 1 to 18 years) presenting with Sturge-Weber syndrome were explored by MRI with contrast injection in 2 cases. The respective positions of CT and MRI are discussed: CT is the method of choice to display leptomeningeal calcifications. MRI seems to be more accurate than CT to determine the location of the lesions and to demonstrate the enhancement of the angioma after contrast injection.

Adolescent↗

Hemispheric asymmetry of late auditory evoked response induced by pitch changes in infants: influence of sleep stages.

Late auditory evoked potentials (LAEPs) have been recorded in response to a 1000 Hz standard (occurrence 80%) or a 2000 Hz deviant (occurrence 20%) tone on the left (T3) and right (T4) temporal scalp in 6-week-old full-term newborns during pure quiet or active sleep states. Sleep states were premanently controlled by polygraphic recording including EEG, EOG, EMG, EKG and respiratory movements. During quiet sleep LAEPs consisted of a clear polygraphic response: N1-P2-N2-P3. Mean latencies ranges on T3 and T4 were: N1 = 28-70 ms; P2 = 343-407 ms; N2 = 966-1178 ms; and P3 = 1461-1492 ms. During active sleep LAEPs consisted of a N1-P2-N2 response. Mean latency ranges on T3 and T4 were: N1 = 36-79 ms; P2 = 278-304 ms; N2 = 555-620 ms. N2 latency was significantly shorter in AS than in QS. Amplitude of the N1-P2-N2 complex was significantly lower during active sleep. In response to standard stimuli, mean amplitudes and latencies of the LAEP were similar on T3 and T4 during active or quiet sleep states. In response to deviant stimuli mean amplitude of the N1-P2-N2 complex was significantly higher and mean latencies of N1 and N2 were significantly shorter on T3 during quiet sleep. No significant difference was observed during active sleep. These results confirm that sleep stages have a considerable influence on cortical auditory pathways. The auditory message is amplified during quiet sleep and inhibited during active sleep. Therefore sleep states need to be controlled to analyze LAEPs in young children.(ABSTRACT TRUNCATED AT 250 WORDS)

Acoustic Stimulation↗

[Repair of complex wounds of the lower limb].

The prognosis of complex open fractures of the lower limbs has radically been altered by recent advances in plastic surgery. Numerous reliable flaps are now available, including muscular, musculo-cutaneous, fascio-cutaneous and septo-cutaneous flaps with a proximal or distal pedicle, and free cutaneous, osseous, osteo-cutaneous etc. microsurgical transfers. Whether homo- or hetero-lateral, these flaps provide an efficient treatment in almost every case. Microsurgery is usually the best method for effective covering of losses of substance that are extensive and/or located in the middle or distal third of the limb. In emergency surgery as well as in surgery of sequelae, the therapeutic indications must be thoroughly discussed.

Fractures, Open↗

[The muscular vascular index. Analysis of the vascularization of the muscles of the forearm].

The results of an anatomic study based on 50 fresh adult cadaver upper extremities are analysed. All the arterial pedicles of each forearm muscle were counted, and each muscle was weighed. Each forearm contained an average number of 264 muscular pedicles. The relative mass fraction of each muscle was calculated, as was its "muscular vascular index" or MVI (number of pedicles divided by the weight of the muscle in grams). Half of the forearm muscles had a significant statistical relationship between their weight and their number of vascular pedicles. The other half had no statistical relationship. These two statistical muscular groups (with and without a statistical relationship) did not clearly correspond to anatomic or functional groups. No muscular group based on the average of MVI was found. Each of the 20 forearm muscle had finally its own characteristics of weight, number of pedicles, and MVI. The average MVI was 0.9 (from 0.4 to 1.8). The global muscular vascular index (GMVI) is the division of the total number of muscular pedicles of a forearm by the total muscular weight of this forearm. The average GMVI was 0.8 (from 0.4 to 1.6). In spite of its theoretical and practical limits, the MVI concept approximately reflects the high vascular density of the forearm muscles.

Analysis of Variance↗

[Electroencephalography, epilepsy and brain tumor].

The authors present a critical analysis of electroencephalographic (EEG) data recorded in children with supratentorial intracranial tumor. They emphasize the value of clinical and EEG presentation in the diagnosis of epileptogenic tumor in children and in the evolution of the children who underwent surgery.

Brain Neoplasms↗

[Contribution of magnetic resonance imaging in 100 cases of refractory partial epilepsy with normal CT scans].

One hundred epileptic patients were included in this study according to the following criteria: intractable partial epilepsy, normal CT scan and focal EEG abnormalities. Eighty-nine patients were suffering from complex partial seizures of temporal or frontal origin, 55 and 34 cases respectively. Eleven patients presented with only simple partial seizures. MRI was abnormal in 31 patients. The abnormalities were: focal T2 increased signal intensity (13 cases) most often temporal (10 cases), cryptic arteriovenous malformation (4 cases), focal T1 and T2 signal abnormality (4 cases), focal atrophy (2 cases) and multiple abnormal T2 signals scattered in the white matter (8 cases). The site of MRI abnormalities was consistent with electroclinical data in 22 patients, of whom 20 had a temporal lobe epilepsy. Thus MRI proved to be more often abnormal in temporal than in frontal lobe epilepsy (36 p. 100 and 5.9 p. 100 respectively) when the CT scan is normal. However MRI data, particularly focal T2 hypersignals should be confronted to electroclinical and metabolic findings whenever functional surgery is considered.

Adolescent↗

Magnetic resonance imaging in refractory focal epilepsy with normal CT scans.

One hundred patients suffering from focal epilepsy with complex partial seizures refractory to medical treatment and showing no abnormality at CT were explored by MRI with an 0.5 Tesla magnet. MRI detected an abnormality in 25 patients with, in 17 of them, good correlation between MRI and clinical as well as electroencephalographic findings. Abnormal morphology and signal was found in 5 patients, with positive CT results on reexamination of previous CT images or on new CT scans in 4 of them. There was a diffuse temporal lobe high-intensity signal in 3 cases and a localized high-intensity signal in 9 cases (temporal lobe 4, occipital lobe 3, frontal lobe 1, fronto-parietal and parietal lobes 1). Thus, in 13% of the cases MRI demonstrated a lesion that had not been detected at CT, and the location of the lesion was concordant with clinical and electroencephalographic data.

Adolescent↗

Effect of sleep on middle latency response (MLR) in infants.

Auditory middle latency responses (MLR), with two click-rates (1.3 Hz, 8.9 Hz) and simultaneous polygraphic recording with EEG, EOG, EMG, ECG and respiratory rhythm have been recorded in 16, 6 or 7 week old infants to study the effect of sleep on the amplitudes of MLR. For both click-rates, response amplitude depended upon waking and sleep states, the Na-Pa complex being always greater during waking states. It is of very low amplitude during quiet and active sleep but significantly lower in quiet sleep. In some infants it disappears entirely in quiet sleep. MLRs have been said to be hard to reproduce in infants. Our results would suggest that this is due to a strong alertness effect on MLRs in infants.

Age Factors↗

[Technic of suturing a peripheral nerve].

Essential practical rules for suture of a peripheral nerve are detailed in the order of the different stages involved: instrumentation, moment of reconstruction, approach route, preparation of nerve extremities, absence of tension, type of suture and postoperative immobilization. Preference is given to epi-perineural sutures.

Humans↗

[Recent traumatic lesions of the male anterior urethra. Apropos of 17 cases].

Seventeen cases of anterior urethral injuries are presented. The authors define the management of these lesions: emergency IVP and suprapubic catheter drainage; after three to five days, retrograde and voiding urethrography and surgical repair: end to end anastomosis when the rupture is complete (8 cases with 7 good results, 1 fair result), in case of partial rupture, surgical repair should be preferred (2 cases with 2 good results); the other alternatives, urethral catheter (2 cases), or suprapubic catheter drainage with delayed treatment of stricture (3 cases), appeared to be less comfortable, contusions must be treated conservatively.

Adolescent↗

[Transitory EEG asymmetry at the start of quiet sleep in the newborn infant: 75 cases].

75 transient EEG asymmetries occurring during quiet sleep were studied. These asymmetries were obtained from 73 polygraphic recordings registered in 73 neonates. These infants represented 3.17% of all the neonates registered during the neonatal period in a department of neonatology (2297 neonates registered between July 1974 and July 1982). The pattern of these asymmetries was always identical, it consisted of a sudden flattening of the EEG activity occurring on one hemisphere followed on this hemisphere by an EEG activity which was more discontinuous and less mature than on the other hemisphere. These asymmetries were transient, lasting from 1 to 5 min. They occurred at the beginning of quiet sleep. The EEG activity before and after the asymmetry was almost always normal. The analysis of the clinical data showed that the infants who presented an EEG asymmetry during quiet sleep had a conceptional age ranging from 35 to 44 weeks, and that they were hospitalized for a minor illness which turned out to be a neurological disorder in only 2 cases. It showed that all the infants who were followed later, except one, developed normally. The physiological mechanism of these asymmetries is discussed and it is concluded that they are functional, probably enhanced by a sleep deprivation and not associated with a focal pathology.

Dominance, Cerebral↗