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Biomedical subjects

M Risko

Publications and source records attributed to M Risko.

6 recordsLinked to original sources
PubMed1992

Urinary glycosaminoglycan excretion in rheumatic diseases.

We used Alcian Blue (AB) and dimethylmethylene blue (DMB) methods to measure glycosaminoglycan (GAG) excretion in the first morning urine specimens of patients with osteoarthritis (OA), ankylosing spondylitis (AS), and rheumatoid arthritis (RA) in different stages of disease. By the AB method, urinary GAG excretion in patients with RA was not different from healthy control subjects. However, the DMB method showed significant differences (in milligrams of GAG per gram of creatinine) for OA (median 25.4, range 14.3-44.0, P less than 0.01, n = 23) and RA patients (median 33.0; range 10.0-147.6; P less than 0.001, n = 63) in comparison with unaffected individuals (median 20.2; range 8.9-41.4, n = 38). We noted a significant difference in urinary GAG excretion between RA and OA patients (P less than 0.01) and between RA and AS (P less than 0.01) patients. The DMB method was further investigated by clinical decision analysis. The DMB method is simple and rapid and may be useful in diagnosing RA by distinguishing between RA and OA or AS.

Adolescent↗
PubMed1986

Lightning artifact in the EEG.

Lightning is highly prevalent in South Florida. The artifact caused by lightning in EEG recordings is of variable duration and seen as abrupt deflection of pens, sometimes followed by sustained pen drift and slow recovery mimicking amplifier overload as caused by rapid unplugging and plugging of the equipment power cable from the wall outlet. Since this artifact was associated to hospital light flickering and was recorded independent of machine location and orientation, we believe it is secondary to extreme brief Mains voltage fluctuations, probably due to horizontal lightning electric field effects rather than radio or electromagnetic interference generated by lightning.

Electroencephalography↗
PubMed1984

Photic induced-driven PLEDs in paroxysmal dystonic choreoathetosis.

An 82-year-old female had rare unilateral spontaneous attacks of paroxysmal dystonic choreoathetosis without loss of consciousness since early adolescence. Her maternal aunt had similar episodes. Previous interictal EEGs never recorded in close association to her attacks had been normal. Photic stimulation at low frequencies during EEG recordings performed near to one of her ictus, induced paroxysmal driven lateralized epileptiform discharges from the contralateral hemisphere. This peri-ictal finding in a patient with paroxysmal dystonic choreoathetosis is unique and suggests this disorder may have some epileptogenic basis.

Aged↗
PubMed1984

EEG features in post-traumatic syndrome.

Standard and 24-hour ambulatory EEG recordings were performed on 54 patients with post-traumatic syndrome that developed after minor closed head trauma or whiplash neck injuries. Paroxysmal activity occurred in 9.2% of patients, either specific or non-specific. While being monitored, 24 patients experienced symptoms typical of this disorder without concurrent EEG abnormalities. No patient exhibited abnormalities in the 24-hour ambulatory recording alone. The symptoms of post-traumatic syndrome were not epileptogenic and the overall incidence of EEG abnormalities in this disorder was low, contradicting some previous reports.

Adolescent↗
PubMed1984

Pseudocataplexy: gelastic-atonic seizures.

Gelastic-atonic seizures are characterized by laughing and then loss of muscle tone. They are difficult to differentiate from laughter-induced cataplexy and may be indicative of Niemann-Pick disease Type C or variants. We studied an 11-year-old girl who had gelastic-atonic seizures that were triggered by laughing. The nature of her attacks was established by ictal EEG ambulatory recordings at home. There was no evidence of Niemann-Pick disease.

Cataplexy↗