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Biomedical subjects

M Rist

Publications and source records attributed to M Rist.

At least 37 records · Page 2Linked to original sources
PubMed1991

[Cutaneous reconstruction of external genital organs: an older method still in current use].

The authors present four patients with cutaneous defects of the genital organs, one with a degloving injury to the penis, one with Fournier's gangrene, one with massive lymphoedema and one with a full thickness burn. In those four cases, a stable coverage was obtained through skin grafts, maintained by an external splint. The use of this older method gave an excellent esthetic and functional result.

Adult↗
PubMed1991

[Familial adult cystic kidneys and malignant teratomas after kidney transplantation with cyclosporin therapy].

We report on two brothers with adult polycystic kidney disease, malignant teratomas and other genital malformations. Because of the unusual accumulation of malformations of embryologically related organs, we postulate a connection between malformations of the kidneys and the genital tract, on the one hand, and teratomas on the other. No genetic coherence is known so far. It is unlikely that immunosuppression with cyclosporin after transplantation had caused these tumours.

Adult↗
PubMed1990

Carcinosarcoma of the prostate in combination with adenocarcinoma of the prostate and adenocarcinoma of the seminal vesicles. A case report with immunocytochemical analysis and review of the literature.

A unique triad of a carcinosarcoma and an adenocarcinoma of the prostate as well as an adenocarcinoma of the seminal vesicles in a 67-year-old man is reported. The carcinosarcoma was investigated by immunohistochemical methods. The mesenchymal parts of the sarcoma showed chondromatous differentiation expressed by S-100 protein and vimentin. The undifferentiated epithelial elements of the carcinosarcoma reacted positively to the panepithelial antibody lu-5 and to carcinoembryonic antigen (CEA). The adenocarcinoma of the prostate stained with antibodies to panepithelial antigen (lu-5), prostatic acid phosphatase, prostate specific antigen and CEA, whereas the adenocarcinoma of the seminal vesicles reacted only to lu-5 and CEA. The literature is reviewed.

Adenocarcinoma↗
PubMed1990

Does microinvasion of the capsule and/or micrometastases in regional lymph nodes influence disease-free survival after radical prostatectomy?

Since 1976, 126 patients with clinically localised carcinoma of the prostate have been managed by radical retropubic prostatectomy. All patients with tumour spread beyond the capsule or metastasis in lymph nodes received radiotherapy. Tumour category pT3 was divided into invasion of the capsule or infiltration of the seminal vesicle. The disease-free 10-year survival rate in patients with minimal invasion of the capsule was 72% and in patients with infiltration of the seminal vesicles it was 26%. Unilateral lymph node metastases were classified as microscopic disease or macroscopic infiltration. The disease-free 10-year survival rate in patients with metastasis in 1 lymph node (micro- and macro-metastasis) was 65% in contrast to 0% in patients with bilateral disease.

Aged↗
PubMed1989

[What does the omentum plug accomplish in colorectal tumor surgery? A 10-year follow-up].

In 23 of 47 patients who underwent surgery for malignant colorectal tumors between January 1978 and December 1986, the residual cavity was treated with a pedicled omental plug after radical resection of the tumor-bearing areas. There was advanced transmural tumor spread in 13 omentum patients and in 9 operated without using omentum. The other patients had equally distributed T2 and T3 stage tumors. Complications were similar in both groups, but perineal infection was slightly less frequent and less significant in the omentum group. Hospitalization was 23 days in patients with the omental plug and 34 days in the others. Life quality, as shown by the activity index, was better in the omentum group. 30-day postoperative mortality was 8.5% in both groups. Individual survival after surgery was 23 months with the omental plug, compared with 15 months in patients without this procedure. At 5 years, however, survival rate was similar. Postmortem revealed no tumor spread alongside the transposed omentum, which had changed to a mesentery-like structure. From these results it is clear that the omentum plug does not achieve cure in carcinoma or longterm survival, but improves the complication rate and individual survival time. We can therefore recommend this procedure as palliative treatment, since even extensive defects can be covered effectively by omentum.

Adult↗
PubMed1989

[Transplantation of kidneys of relatives].

In the last few decades kidney transplants have shown an increasing survival rate of about 85% after one year. The growing demand for transplants is limited by the insufficient availability of kidneys and the living donor represents a possible means of reducing the discrepancy between supply and demand. We report here results of 41 transplantations from related, living donors. The overall transplant survival rate at one year was 91% and at 5 years 71%. In the group treated with cyclosporine the survival rate was 92% at 5 years. The mean serum creatinine levels at the latest follow-up was 115 mumol/l, while the mean blood pressure was 139/82 mmHg. Donor nephrectomy resulted neither in morbidity nor mortality. An extensive follow-up study of 8 donors revealed normal values for both blood pressure and serum creatinine. Careful donor selection is crucial in order to guarantee the voluntary nature of donation and, thus, to avoid the risk of commercialism.

Follow-Up Studies↗
PubMed1987

Regional cerebral blood flow in man at rest and during exercise.

Regional cerebral blood flow (rCBF) of the left hemisphere was measured in 12 healthy young men at rest and during physical work on a bicycle ergometer in the supine position at work-load levels of 25 W or 100 W using the intravenous 133Xe method. Regional mean cerebral blood flow, regional gray-matter flow, and relative gray-matter weight was determined for six regions of interest. Arterial blood pressure, pulse frequency and expiratory CO2 concentration were recorded. Cerebral blood flow in all regions was significantly (P less than 0.001) higher during exercise than at rest. The increase in the 100 W group (24.7%) was significantly (P less than 0.05) greater than in the 25 W group (13.5%), but resting blood flow levels and alveolar CO2 concentrations were also different in both groups. Mean arterial blood pressure, pulse frequency and alveolar CO2 concentrations, but not arterial pCO2, were significantly higher during exercise and there was a faster washout of whole-body xenon. The CBF increase was interpreted as a combined effect of elevated systemic blood pressure and functionally activated brain metabolism. There was no evidence of impaired cerebral autoregulation.

Adult↗
PubMed1987

[Functional disorders of bladder emptying in adulthood].

Functional voiding problems can be divided into three different groups: neurogenic dysfunction, myogenic dysfunction and true functional impairment of micturition in the sense of a psychosomatic disorder. Patients should be classified in the latter group only, if somatic disorders are excluded by conscientious urologic examination. Treatment of these patients is very time-consuming and difficult. Pure myogenic dysfunction occurs with rare generalised muscle disease only. Neurogenic dysfunction represents the majority of cases. Investigations in the Swiss Centre for Paraplegics and some new publications point out fundamental tendencies in the therapy and rehabilitation of neurogenic bladder dysfunction.

Adult↗
PubMed1983

Tissue polypeptide antigen (TPA) and prostatic acid phosphatase in serum of prostatic cancer patients.

Tissue polypeptide antigen (TPA) and prostatic acid phosphatase were both detected by radioimmunoassay in the sera of a male population (age greater than 45 years) consulting the clinic for urological problems or check-up on treatment. Increased concentrations of TPA were associated mostly with advanced stages of prostatic carcinomas, parallel to PAP. Some enhanced TPA concentrations were detected with haematuria and adenomas of the prostate.

Acid Phosphatase↗
PubMed1982

[Phenacetin abuse. VII: Urinary tract tumors in dialysis patients and patients with kidney grafts].

From 1965 to 1981, 9 out of 346 patients treated by chronic hemodialysis or kidney transplants had tumours of the lower urinary tract. All the tumour patients belonged to the analgesic abusers group (n = 87). The frequency of urinary tract tumours in this analgesic abusers group does not differ from the frequency in analgesic abusers in general (about 10%). In the 9 analgesic abusers a total of 18 urothelial tumours were recorded: 4 tumours of the renal pelvis, 3 of the ureter and 8 tumours of the urinary bladder. One female patient had a tumour of the urethra. Diagnostic and therapeutic problems are discussed on the basis of two case histories. Our experience in recent years is summarized in a program for tumour-screening, diagnosis and therapy for analgesic abusers treated by dialysis and kidney transplantation.

Carcinoma, Squamous Cell↗