Biomedical subjects
Publications and source records attributed to M Roccasalva.
Pasteurella are common bacteria among healthy animals. Humans usually are infected by dog and cat bites or scratches. Besides, local skin infection, Pasteurella may spread, in some cases, to lungs, joints, bones or, less frequently, to other organs.
A 76-year-old woman with a chronic leg ulcer for the last thirty-seven years was hospitalized in our institution for chronic diarrhea and terminal kidney failure with proteinuria. The diagnosis of secondary amyloidosis due to persistent skin inflammation was confirmed by aspiration of subcutaneous abdominal fat and by kidney biopsy which showed AA type systemic amyloidosis. This appears to be a rare complication of chronic leg ulcers as there have been only eight publications covering eleven cases in the literature.
In the hard electroplating process, chromium exposure is heavier than in the bright process. The average urinary chromium was 9,7 +/- 7,2 micrograms/g cr. in the 31 bright plating subjects; comparing only the chromium bath workers of the two process, the difference was statistically significant (13,0 +/- 7,5 micrograms/g cr. against 7,6 +/- 4,4 micrograms/g cr. t = 2,4; p less than 0,0025). In a control group composed of 22 sanitary workers, the average urinary chromium was 1,9 +/- 1,4 micrograms/g cr. We found chromium rhinopathy in 40% of the hard process subjects and in 20% of the bright process subjects. Sputum cytologic examination was not correlated with the chromium level exposure. In the exposed workers we found 37% insufficient specimens and 53% metaplasia plus dysplasia; in the 42 control subjects we found 64% insufficient specimens, 33% metaplasia and no dysplasia.