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M Rodenburg

Publications and source records attributed to M Rodenburg.

39 records · Page 3Linked to original sources

Distribution of brain stem responses to acoustic stimuli over the human scalp.

Responses to acoustic stimuli are generated in neurons of nuclei on both sides of the brain stem. In order to determine whether there are electrode positions which can be used to record activity predominantly generated in the neurons of nuclei of one side, the distribution of brain stem responses to acoustic stimuli over the human scalp was investigated. The response is found to be maximum at the vertex, and diminishes gradually toward the nasion, inion and the mastoid process. There are no significant differences between responses to ipsi- and contralateral stimulation. It follows that there are no electrode positions, which can be used to record the activity generated in the neurons of nuclei of one side. There are, however, indications that monolateral pathology of brain stem nuclei may be detectable by comparing responses to stimuli presented on the right, the left and bilaterally.

Acoustic Stimulation

Electro-cochlear potentials elicited by sinusoidally modulated signals.

Responses of the guinea pig cochlea to amplitude-modulated stimuli were measured with the aid of a gross electrode. The dynamic characteristics of this part of the auditory system was studied by varying several parameters of the applied signal. The signals used as carriers in our experiments were either white noise or pure tones of 1 and 4 kHz. The modulation frequency, dynamic and intensity characteristics were determined by varying the modulating frequency, the modulation depth and the intensity of the applied signal. To get an idea about possible non-linear aspects of the system under investigation, we always computed the Fourier transform of the response data and plotted the amplitude of the various harmonics and the phase of the fundamental separately as functions of the signal parameter in question. The greatest response was always found at a modulation frequency of about 200 Hz, with a relatively gradual rise up to this frequency and a sharper drop above 200 Hz. The phase of the fundamental changes very rapidly at frequencies above Hz. The distortion is mainly second-harmonic and has a maximum about 1 octave lower than the fundamental. The carrier frequency and the intensity of the stimulus were not found to have a great influence on the frequency characteristic. For small modulation depths, the system is nearly linear; at higher intensities and modulation depths saturation occurs, coinciding with a relative increase in the intensity of the second harmonic with respect to the fundamental.

Acoustic Stimulation