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M Rohrbach

Publications and source records attributed to M Rohrbach.

29 records · Page 2Linked to original sources
PubMed1991

[Routine screening for Chlamydia: is it sensible during pregnancy?].

610 pregnant patients were examined for evidence of Chlamydia trachomatis infection. Chlamydia trachomatis could be detected in 18 of these 610 patients. This results in a low prevalence rate of 3%; therefore, screening for Chlamydia trachomatis is not indicated in our pregnant population. Among the 18 chlamydia-positive patients we could not discover any risk factors that were associated with this infection. Because of the varied and sometimes silent course in affected patients, this special investigation should be used liberally in a variety of situations.

Adult↗
PubMed1989

Irradiation of choroidal melanomas before enucleation?

The eyes of 26 patients with choroidal melanomas were irradiated before enucleation at the University Eye Clinic in Tübingen. Preoperative external beam radiation therapy (PERT) was administered between July 1980 and July 1986. Follow-up ranged from 25 months to 8 years, 4 months with a mean follow-up of 53 months. The average diameter of the tumor base was 15 mm and the height 10 mm. Before enucleation vertical stationary electron beam irradiation (10-12 meV) was applied to the tumor-containing eye and the orbit. The dose was increased during the course of the study from 12 to 40 Gy. Enucleation was performed by a technique that cauterized the vasculature before severing it and avoided maneuvers that would cause changes in intraocular pressure. The patients were reexamined between August and November 1988. Nine (34.6%) had died of metastases of melanoma, six of them during the second postoperative year; one patient was alive with metastases. Subsequent death occurred in all patients who had melanomas of epithelioid cell type (3 of 3) and in no patients who had melanomas of spindle A cell type (0 of 3). In this small series PERT had no apparent beneficial effect on the patient's life expectancy.

Adult↗
PubMed1988

[Which are the most frequently occurring enteropathogenic bacteria in clinical practice?].

Diarrhea is an increasingly frequent clinical finding in Swiss medical practice. One reason is the volume of tourism in countries with different climatic and social circumstances. To obtain an overview of the enteropathogenic bacteria spectrum as a cause of diarrhea, we analyzed 11,163 stool specimens from a representative group of patients throughout Switzerland. Enteropathogenic bacteria were found in 15.2% of all specimens; 50% were Campylobacter jejuni/coli, 35% Salmonella spp., 8% Aeromonas hydrophila group, 4% Shigella spp. and 3% Yersinia enterocolitica. This distribution is taken for all age groups and for both sexes. In the infant age there was a maximum evidence of enteropathogenic bacteria of the female sex. In childhood this maximum concerned to the male sex. Patients older than fifty had no positive stool specimens. As expected the most frequent positive stool specimens were in summer.

Aged↗
PubMed1988

[Chlamydia diagnosis in clinical practice. Chlamydia trachomatis EIA and direct immunofluorescence (MikroTak) in comparison with cell culture].

The correct obtaining of material is decisive for microbiological diagnosis. The new immunologic methods, enzyme immunoassay (Chlamydiazyme) and the direct immunofluorescence with monoclonal antibodies (MikroTrak) for the detection of Chlamydia trachomatis have several advantages over cell culture. In 457 tests of urethral smears from men with all 3 methods, sensitivity and specificity were compared with cell cultures as method of reference. Tests with Chlamydiazyme yielded a concordance of 87.1%, a sensitivity of 81.5% and an specificity of 87.8%. Tests with MikroTrak were almost identical with a concordance of 86.9%, a sensitivity of 81.3% and a specificity of 87.5%. With both methods, the positive predictive value with 43.8% and 43.3% respectively is low. Frequent positive results with the immunological methods, which could not be verified by cell cultures, must be interpreted as failure of the culture method under practice conditions. The correlation of results with the clinical course supports this assumption.

Adult↗
PubMed1988

[Is there a cloacal window in the human embryo?].

Three- and four-day-old chicken embryos show normally a defect in the epithelium of the cloacal wall. This defect is not seen in human embryos at a similar developmental stage. Its signification is unknown.

Animals↗
PubMed1986

Quantitative analysis of 'plaque material' in the inner- and outer wall of Schlemm's canal in normal- and glaucomatous eyes.

The amount of plaque material derived from the sheaths of the elastic-like fibers in the cribriform layer of the trabecular meshwork (sheath-derived or SD plaques) was quantitatively evaluated in normal eyes and in trabeculectomy specimens of chronic simple, intermittent angle closure, and pseudoexfoliation glaucoma. The amount of SD plaque material increases with age but no correlation between age and SD plaques was found in any of the glaucomas evaluated. In comparison to normal eyes, the amount of SD plaque material was significantly greater in cases of chronic simple glaucoma and in cases of intermittent narrow angle glaucoma, but not in pseudoexfoliation glaucoma. In the latter, number and distribution of SD plaques resembled those of normal eyes. SD plaques were also found in the outer wall of Schlemm's canal. In normal eyes there was a correlation between outer-wall plaques and age as well as between inner- and outer-wall plaques. These correlations were not found in the different types of glaucoma. Our findings indicate that in addition to the age-related increase in plaque material, there is in glaucomatous eyes some plaque material which is distributed unevenly in the inner- and outer-wall of Schlemm's canal. This additional material was not found in pseudoexfoliation glaucoma, indicating that elevated intraocular pressure alone can not be responsible for plaque formation.

Adolescent↗
PubMed1986

Quantitative analysis of 'plaque material' between ciliary muscle tips in normal- and glaucomatous eyes.

Between the anterior ciliary muscle tips in normal and glaucomatous eyes, different forms of plaque material were found within the intermuscular connective tissue. These plaques derive from either the sheaths of the elastic-like fibers or the elastic tendons of the anterior ciliary muscle tips. In addition, there are plaques which have the characteristics of the hyalinized basement membranes of the trabecular beams. The quantitative evaluation of all three types of ciliary muscle (c.m.) plaques showed that in normal eyes the amount of c.m. plaques increases with age and correlates with the amount of plaques in the inner wall of Schlemm's canal. In cases of chronic simple glaucoma the amount of c.m. plaques did not significantly correlate with age, but the absolute amount of this material was significantly higher than in normal eyes. No correlation between inner wall and c.m. plaques was found, indicating that in glaucoma additional factors besides age contribute to plaque formation.

Adult↗
PubMed1985

[Clinical evaluation of the Gonozyme enzyme immunoassay in comparison with the modified Thayer-Martin medium and the Jembec transport medium].

A solid phase enzyme immunoassay (GC-EIA, Gonozyme Abbott) for detection of Neisseria gonorrhoeae was tested in 185 male patients with urethritis purulenta sive serosa, and compared with the results obtained by bacterial culture. In 69 men gonorrhoea was confirmed by bacterial culture as method of reference. In 60 patients detection of Neisseria gonorrhoeae was carried out by means of direct inoculation on to Thayer Martin selective medium and immediate incubation, as well as on Jembec transport medium, which was mailed once a day to the respective laboratory. In 8 cases, N.go. was diagnosed with the Thayer-Martin medium only, in 1 case with the Jembec medium only. In 68 out of the 69 patients (sensitivity 98.6%) diagnosis was established with Gonozyme. An additional 8 positive results were obtained with this test, which could not be confirmed by bacterial culture (specificity 93.1%). 2 of these so-called false positive results can with great probability be assessed as true positive results on the basis of the case history. The positive predictive value with the Gonozyme method was 81.5% and the negative predictive value was 99.1%. The advantages, disadvantages and indication for this method are discussed and compared with the experience of other authors to date.

Adult↗