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Biomedical subjects

M Rollet

Publications and source records attributed to M Rollet.

At least 19 recordsLinked to original sources
PubMed1988

Dry adsorbed emulsions: an oral sustained drug delivery system.

The oral sustained drug delivery system "dry adsorbed emulsion" was defined as an organized dispersion of hydrophilic and hydrophobic particles whose structure was initiated by the structure of a water-in-oil (W/O) emulsion. Sodium salicylate was dissolved in the aqueous phase of the primary W/O emulsion as an active drug. The aqueous phase of the W/O emulsion was adsorbed by a hydrophilic silica and then a hydrophobic silica was added to the preparation to obtain a stable and solid pulverulent form. The physicochemical structure of a "dry adsorbed emulsion" was described and observed by electron microscopy. The effect of different oils, castor oil and a silicone oil, on the sustained drug release was studied at two different pH values, 1.2 and 7.4, to simulate the gastric and intestinal medium, respectively. The properties of these forms were retained for more than one year at room temperature storage.

Adsorption↗
PubMed1986

The clinical utility of pacemaker follow-up visits.

Because of the increased complexity of modern pacemakers, pacemaker follow-up visits in specialized centers become more and more indispensable. In this study, the results of 15,000 outpatient visits to the cardiac pacing center between the years 1983-1985 are presented. In most cases (92.8%), verification of normal function was made; however, mandatory reprogramming was required in 1.2%, and hospitalization for various reasons was required in 6% of visits. Careful outpatient monitoring of pacemakers is therefore very important for detecting early or late pacemaker complications.

Electrocardiography↗
PubMed1982

[Computers in a center for cardiac stimulation].

The authors describe a computer system with details of the hard ware and filing organisation. The sophistication and originality of the programme makes it a multipurpose tool base on a condensed dictionary. Its uses may be summarised under three headings: --The upkeep of medical case notes, a very successful application, resulting in improved safety in the long term follow-up of pacemaker patients. Statistical analysis of multiple parameters in larger series of patients is possible, a task which could not be carried out without a computer. --The system has the advantage of providing secretarial help in the booking of follow-up appointments, automatic print-out of follow-up reports and letters to the referring physician. This leads to better efficiency in correspondence. --The third advantage is the stocking and treatment of numeric data on a wide range of materials, leading to the creation of its own data bank. The programme as described has been adopted for cardiology and, in particular, cardiac pacing. It could, however, be applied in all fields of medicine, especially those using other materials (valvular prostheses, orthopedic appliances, etc).

Adult↗