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Biomedical subjects

M Rouse

Publications and source records attributed to M Rouse.

5 recordsLinked to original sources

An open, randomised, parallel group study of lactulose versus ispaghula in the treatment of chronic constipation in adults.

The efficacy, tolerance and acceptability of lactulose (Duphalac) and ispaghula (Fybogel Orange) were assessed in the treatment of chronic constipation in adults. In an open, prospectively randomised, parallel group study, 124 patients with a history of constipation for more than three weeks were treated with either 15 ml bd of lactulose (increasing to 60 ml daily if necessary) or one sachet bd of ispaghula. Over the four-week treatment period both treatments were shown to be effective, and numbers of concurrent effects were similar between the two groups. Differences were demonstrated with regard to acceptability in favour of lactulose.

Bicarbonates

Ciprofloxacin therapy of experimental endocarditis caused by methicillin-susceptible or methicillin-resistant Staphylococcus aureus.

Ciprofloxacin was more effective (P less than 0.01) than either imipenem or nafcillin therapy of experimental methicillin-susceptible Staphylococcus aureus endocarditis in rabbits after 2 or 3 days of treatment. There was no significant difference between results of treatment of methicillin-susceptible S. aureus experimental endocarditis with ciprofloxacin and results with the combination of nafcillin and gentamicin. Ciprofloxacin was more effective (P less than 0.01) than vancomycin therapy of experimental methicillin-resistant S. aureus endocarditis after 3 days of treatment. After 5 days of treatment, there was no significant difference between the results of treatment of experimental methicillin-resistant S. aureus endocarditis with ciprofloxacin and results with vancomycin.

Animals

Social adjustment and alcoholism among Chinese immigrants in New York City.

Based upon the patient files (N = 132) maintained by the Chinatown Alcoholism Services (CAS), interviews with CAS staff, and the clinical experience of the authors with Chinese alcoholics, this paper describes the social contexts of alcoholism among a group of working-class Chinese males in New York City. It focuses on the relationship between social adjustment and drinking behaviors, and analyzes the meaning of alcohol use and abuse within the ethnic community. The paper also examines the role of significant others in the alcoholics' drinking and help-seeking behaviors. Finally, treatment and research issues pertaining to alcoholism among the Chinese are discussed.

Acculturation