Biomedical subjects

M Ruiz Fernández

Publications and source records attributed to M Ruiz Fernández.

4 recordsLinked to original sources

PubMed1998

[Complex implantation of an automatic defibrillator-cardioverter through a left superior vena cava].

We describe the case of a 19-year-old girl with a left superior vena cava and a surgically corrected complete atrioventricular canal defect. After an inhospital sudden death an automatic defibrillator-cardioverter was implanted through her left superior vena cava. During the postoperative course, multiple inappropriate discharges caused by myopotential oversensing indicated the relocation of the electrode and, finally, insertion of two epicardial leads by a left submammarian thoracotomy approach, produced an optimal result.

Adult↗

PubMed1997

[Severe chronic ischemic ventricular dysfunction. Determinants of surgical risk and long-term clinical outcome].

INTRODUCTION: In patients with chronic ischemic heart disease, a severe ventricular dysfunction is associated with a higher operative risk and to a worse late clinical outcome. However, when there is sufficient viable myocardium, surgical revascularization can improve ventricular performance and above all the functional capacity and survival of these patients. OBJECTIVES: To analyze long-term results of a large series of patients with an ejection fraction < or = 0.30 that underwent isolated coronary artery bypass surgery and to investigate factors, mainly clinical, that determined favorable clinical results: being that the patient was alive and free of incapacitating symptoms. PATIENTS AND METHODS: This series included 100 patients, 93 males and 7 females, with a mean age of 62 +/- 8 years. The predominant clinical manifestation was angina in 37, congestive heart failure in 22 and both in 41. Seventy-nine patients were in functional class III or IV, and 19 had emergency surgery. RESULTS: There were 10 in-hospital deaths, 6 of which occurred in patients who had emergency surgery. Mortality in the elective cases was 4.9%. Only age (p < 0.05), functional class (p < 0.05) and emergency surgery (p < 0.0001) were identified as independent predictors of early mortality. Actuarial survival rates after 5 and 8 years were 65 and 52% respectively. Long-term clinical outcome was considered favorable in 66 patients. We did not find any preoperative clinical variables that were predictors of the clinical outcome. Only preoperative mitral insufficiency correlated with a poor long-term clinical result. CONCLUSIONS: Patients with chronic and severe ventricular dysfunction secondary to coronary artery disease have an acceptable surgical risk when they are operated on electively, before their clinical condition deteriorates. Long-term results are satisfactory in the majority of the patients. In these types of patients clinical manifestations are of limited value in the selection process for surgical revascularization.

Age Factors↗

PubMedDate not supplied

[Latex allergy in a population at risk].

BACKGROUND: The allergy to latex is an illness whose prevalence has been increased in very significant form in the last years. OBJECTIVE: To know the allergy incidence to latex in population of risk, as well as to identify the related sintomatology and the importance or paper that play the atopia antecedents and time of contact with latex for the development of the illness. METHOD: We carry out a prospective, descriptive, experimental and traverse study in population of risk, in the service of Allergy and clinical Immunology of the Hospital Regional Lic. Adolfo López Mateos, ISSSTE. One hundred patients of both sexes were included, with age of 20 to 50 years, with the antecedent of being personal medical and paramedic and to have presented contact with latex material in a minimum period of one year. They were carried out clinical history with registration of sintomatology nasal, bronchial, cutaneous and associated to contact with latex. They were carried out cutaneous test for prick to latex with positive control with the help of histamine solution and negative control with solution of Evans and immediate reading of the same one. RESULTS: 22% of the patients in study, they presented positive skin test latex, with a time of exhibition 10 year-old average, 68% presented antecedent of atopy personal, family and, likewise the associate sintomatology was in a 33.3% dermatology, 54.5 nasal, nobody presented bronchial symptoms and a 9% asymptomatic was reported. CONCLUSION: We support that the immediate skin test latex for Prick is an important parameter of support diagnosis for allergy to type 1 latex.

Adult↗

PubMedDate not supplied

[Leukotrienes in asthma].

The objective of the present article is to revise the biochemical and pharmacological knowledge of the leukotrienes, including the enzymatic and cellular processes that participate in its synthesis. The half-filled biological effects through diverse receptors as the cystenil-leukotrienes, have a primordial participation in the physiopathology of the asthma. The 5-lipooxigenase inhibitor, 5-lipooxygenase-activating protein antagonist, and cystenil-leukotrienes, are three classes of new modulators for clinical use. Their effect has been revised in diverse clinical models of asthma, as the one induced by allergens, exercise, aspirin and in multicenter asthma trials are reviewed. The conclusions in general guide to that their pharmacology and the clinical experience that one has, contain them as a new therapeutic role in the treatment of the asthma.

Animals↗