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Biomedical subjects

M Ruiz-Cabello Jiménez

Publications and source records attributed to M Ruiz-Cabello Jiménez.

8 recordsLinked to original sources

[Thromboembolic complications in inflammatory bowel disease].

Thromboembolic complications during the course of inflammatory bowel disease are infrequent but are mainly found in young patients and are associated with a high morbimortality. The etiopathogenesis of these complications has been widely debated and the existence of coagulation alterations and fibrinolysis have been suggested. Nonetheless, the mechanism must be complex since not only do not all the patients with these alterations present this complication but neither do all the patients with thromboembolism have recognized coagulation disorders. The most common clinical presentation is deep vein thrombosis with pulmonary embolism with arterial thrombosis being rare. Five patients with Crohn's disease and two with ulcerative colitis who presented a total of new thromboembolic episodes, six arterial (1 in primitive iliac artery, 1 in common femoral artery, 1 in humeral-axillary artery, 2 in internal carotid and 1 in superior mesenteric artery) and three of venous localization (1 in brachyocephalic-subclavian trunk, 1 axillary and 1 iliac-femoral/pulmonary thromboembolism) are reported. An updated review of the etiopathogenesis, presentation, treatment and prophylaxis of the thromboembolic complications of inflammatory bowel disease is presented.

Adult↗

[Wegener's granulomatosis with gastrointestinal involvement].

Wegener's granulomatosis is a necrotizing granulomatous vasculitis often characterized by involvement of the upper respiratory tract, lungs and kidney, although any organic system can be affected. We present the case of a female patient with Wegener's granulomatosis diagnosed by biopsy of the kidney, and severe gastrointestinal bleeding with fatal course. Endoscopic findings of the colon and the histopathology of the biopsy are discussed.

Acute Disease↗

[Primary pulmonary hypertension associated with portal hypertension in a cirrhotic female patient].

We present the case of a 28-year-old woman with hepatic cirrhosis, portal hypertension and hypersplenism associated with primary oligosymptomatic pulmonary hypertension, who had a survival somewhat longer than usual (10 years since she was diagnosed as pulmonary hypertension). The patient died in hepatic coma after upper gastrointestinal bleeding. The association between portal and pulmonary hypertension is rare, its true prevalence not being known and its pathogenesis being unclear. We remark the diagnostic tools and therapeutic possibilities.

Adult↗